50 results about "Guaianediol" patented technology

The invention provides a Ni-molybdenum oxide / Nb2O5 nano composite catalyst as well as a preparation method and application thereof, and belongs to the technical field of catalysts. The catalyst precursor is prepared by adopting an excessive impregnation method, then the Ni-molybdenum oxide / Nb2O5 nano-composite catalyst is prepared by adopting a hydrogen reduction treatment method, active components in the catalyst are uniformly loaded, and the catalyst has excellent self-hydrogen hydrothermal catalytic performance. The Ni-molybdenum oxide / Nb2O5 nano composite catalyst prepared by the invention can minimize the dissociation energy of a C-O bond, promote the breakage of the C-O bond, enable the reaction to be carried out in a forward direction, and realize high-value conversion of guaiacol to catechol under mild reaction conditions without exogenous hydrogen.

The present invention discloses a bio-based benzoxazine monomer-modified epoxy resin and a preparation method thereof. The method comprises: reacting guaiacol, ethanolamine, and paraformaldehyde to obtain a bio-based benzoxazine monomer; reacting the bio-based benzoxazine monomer with phosphorus oxychloride in a solvent to obtain a benzoxazine phosphate monomer; and uniformly mixing the benzoxazine phosphate as a modifying curing agent, a bio-based diamine Priamine 1074 as a toughening curing agent, and a bisphenol A-type epoxy resin (DGEBA). The mixture is poured into a mold, and then heated and cured to obtain the bio-based benzoxazine monomer-modified epoxy resin. The bio-based benzoxazine monomer-modified epoxy resin obtained by the present invention has strong mechanical properties and thermal stability, as well as excellent adhesion, flame retardancy, low dielectric properties, and biodegradability.

The invention discloses a 3-hydroxyisovaleric acid and guaiacol composition and application of the 3-hydroxyisovaleric acid and guaiacol composition in preparation of a medicine for treating or preventing glucose metabolism disorder. The invention provides a strategy for treating metabolic diseases by combining 3-hydroxyisovaleric acid and guaiacol for the first time. It is found that combination of the two has a significant synergistic effect, and combination of low doses is superior to single use of high doses. Systematic animal experiments prove that the traditional Chinese medicine composition has a remarkable effect of improving blood sugar, insulin resistance and fatty liver.

The application discloses 4-propyl guaiacol oxidase mutants, a preparation method and application thereof, wherein wild-type 4-propyl guaiacol oxidase is from Penicillium simplicissimum Penicillium simplicissimum ​ The active center of the wild-type 4-propyl guaiacol oxidase is reformed by using a directed evolution method, and 4-propyl guaiacol oxidase mutants D170E, S426T, S50Q / D170E, D170E / L411V and D170E / L411V / S106C with high activity, cis-trans selectivity and trans-isoeugenol yield are obtained, efficient synthesis of high-value trans-isoeugenol from cheap 4-propyl guaiacol is realized, and the industrialized synthesis and application of the trans-isoeugenol are facilitated.

The invention discloses application of guaiacol in treatment of rheumatoid arthritis, and particularly relates to application of guaiacol in preparation of drugs for treating rheumatoid arthritis. Cell experiments prove that guaiacol can effectively down-regulate expression of proinflammatory factors in macrophages and up-regulate expression of anti-inflammatory factors, and has remarkable anti-inflammatory activity; animal experiments show that the guaiacol effectively relieves rheumatoid arthritis model mouse diseases, and the specific manifestation is that the guaiacol obviously relieves the mouse claw swelling degree, reduces the arthritis disease score, obviously improves joint inflammatory cell infiltration, repairs cartilage injury, inhibits osteoclast generation and reduces the number of joint apoptotic cells; meanwhile, the level of proinflammatory factors in serum of mice can be effectively reduced, and the level of proinflammatory repair factors can be up-regulated. The invention proves that guaiacol has a definite curative effect on rheumatoid arthritis, good biological safety and no obvious side effect, provides a new effective active component for the treatment of rheumatoid arthritis, and has a good prospect of being developed into the medicine for treating rheumatoid arthritis.

The invention discloses a copper molybdate catalyst, a preparation method, application and a method for producing 4-propyl phenol. A preparation method of a copper molybdate catalyst for catalyzing demethoxylation of 4-propyl guaiacol comprises the following steps: mixing water-soluble molybdate, water-soluble copper salt and water to obtain a metal aqueous solution; and concentrating, drying and calcining the metal aqueous solution to obtain the copper molybdate catalyst. The preparation method is simpler to operate and more environmentally friendly, the prepared copper molybdate catalyst can be used for catalyzing 4-propyl guaiacol to remove methoxy so as to produce 4-propyl phenol, and the catalytic performance and stability are excellent.

Use of guaijaverin in preparation of an eye protection product is provided, belonging to the technical field of biomedicine. Use of guaijaverin in preparation of an eye protection product is provided. In Examples, a human retinal primary Müller cell optical damage model, a zebrafish eye damage model by blue light, and a mouse retinal optical damage model are constructed in vitro separately. Based on an eye-protection effect of the guaijaverin, further development may be conducted on drugs for treating retinal optical damage-related diseases and functional products for alleviating visual fatigue.

The present invention relates to lignin comprising beta-O-4'units bound in position to one or more compounds of formula (I), such as phenol, catechol, resorcinol, hydroquinone, pyrogallol and / or guaiacol, a process for its preparation and its use. And lignin fragment 1.

The invention relates to application of guaiacol or a derivative thereof in preparation of a medicine for preventing or treating metabolic syndrome, and belongs to the technical field of medicines. The guaiacol and the derivative thereof provided by the invention have the advantages that by regulating a fat metabolism pathway, the insulin resistance condition is obviously improved, the inflammatory response and oxidative stress injury are relieved, and the prevention and treatment on the metabolism-related fatty liver disease (MASLD), hyperlipidemia, hypercholesteremia, obesity and diabetes mellitus are realized through the synergistic effect of multiple dimensions.

The invention discloses a diatom-loaded amorphous cerium oxide electrocatalyst and a preparation method and application thereof, and relates to the technical field of catalyst material synthesis and biomass value materials.The preparation method comprises the steps that amorphous cerium oxide is dispersed in absolute ethyl alcohol, then metal salt is added for ultrasonic treatment, and a precursor is obtained; and after the treatment is completed, obtaining a precipitate, and calcining the precipitate in an H2 / Ar atmosphere at 500-800 DEG C for 5-10 hours to obtain the diatom-loaded amorphous cerium oxide electrocatalyst. The electrocatalyst prepared by the invention has high atom loading capacity, high selectivity and multiple active sites, and shows excellent electrocatalytic performance when being applied to electrochemical catalysis of guaiacol hydrodemethylation to produce catechol.

The application relates to application of guaiacol or a derivative thereof in preparation of a medicine for preventing or treating metabolic syndrome, and belongs to the technical field of medicines. The guaiacol and the derivative thereof provided by the application can significantly improve insulin resistance conditions by regulating a fat metabolism channel, and can simultaneously reduce inflammatory reaction and oxidative stress damage, and can realize prevention and treatment of metabolic associated steatohepatitis (MASLD), hyperlipidemia, hypercholesterolemia, obesity and diabetes through synergistic action in multiple dimensions.

This invention discloses a highly selective synthesis method for isovlandrin, comprising the following steps: Step S1, reacting guaiacol with a benzylating agent in the presence of an alkaline catalyst and an organic solvent to generate o-benzyloxyanisole; Step S2, reacting the o-benzyloxyanisole with a Vilsmeier-Haack reagent for formylation to obtain 3-benzyloxy-4-methoxybenzaldehyde; Step S3, mixing 3-benzyloxy-4-methoxybenzaldehyde with a 65wt%-70wt% aqueous sulfuric acid solution to perform an acid debenzylation reaction to obtain crude isovlandrin; Compared with the prior art, the yield of isovlandrin can reach up to 70% or more, and the selectivity is greatly improved.

A process for producing rotundone from α-guaiene, in particular by oxidation of the C(3) position, wherein the α-guaiene is produced from a precursor by a sesquiterpene synthase. The sesquiterpene synthase is produced in a microorganism.

The application discloses a method for in-situ aqueous phase catalytic conversion of guaiacol and lignin into phenolic compounds, and belongs to the technical field of catalytic conversion for preparing phenolic compounds. The method adopts guaiacol or lignin to selectively generate phenol through HDO under the action of a Ni / MgO catalyst. In the absence of external hydrogen and under environmentally-friendly conditions, a one-pot reaction of the Ni / MgO catalyst can obtain a phenolic (phenol and methyl phenol) yield of up to 12.1 wt% from industrial lignin. The application opens up a non-noble metal catalytic strategy, realizes the conversion from renewable lignin resources to phenolic compounds in the absence of external hydrogen, and is consistent with the concept of green chemistry and sustainable development.

The present invention relates to a process for the preparation of catechol and use of said catechol directly for the preparation of guaiacol, guaethol, vanillin and ethylvanillin.

The invention belongs to the technical field of guaiacol hydrogenation catalysts, and particularly relates to a mesoporous SiO2 coated Mo2C-Co core-shell nanoparticle catalyst as well as a preparation method and application thereof. According to the invention, Mo2C-Co metal nanoparticles and mesoporous silica coated outside the Mo2C-Co metal nanoparticles are adopted to form a catalyst, and high activity, high stability and unprecedented high cyclohexanol selectivity in a hydrodeoxygenation reaction of guaiacol are realized through a unique core-shell structure (Mo2C-Co core + mesoporous SiO2 shell) and a bimetallic synergistic effect (Mo2C and Co) of the catalyst. The invention not only provides a high-efficiency catalyst for solving the key problem of product selectivity control in biomass conversion, but also opens up a more attractive green path for producing a high value-added chemical cyclohexanol, and has remarkable technical advantages and application prospects.

The invention discloses a catalyst, a preparation method and application thereof, and a production method of 4-propyl phenol. The invention relates to a catalyst for a demethoxylation reaction of 4-propyl guaiacol, which is a Cu-Mo-SiO2 catalyst and is formed by a molybdenum-containing inorganic substance, a copper-containing inorganic substance and a silicon-containing organic substance, based on the total mass of the catalyst, the mass fraction of the Mo element is 14.8-16.3 wt%, and the mass fraction of the Cu element is 0.9-9.8 wt%. The catalyst can be used for catalyzing 4-propyl guaiacol to demethoxylate in a fixed bed reactor so as to generate 4-propyl phenol.

The invention discloses a CoOx / ZSM (Zeolite Socony Mobil) catalyst as well as a preparation method and application thereof, and the preparation method comprises the following steps: loading cobalt on a ZSM-5 molecular sieve by a wet impregnation method, and drying to obtain a precursor; calcining the precursor in air, and calcining and reducing in hydrogen to obtain the CoOx / ZSM catalyst. The method comprises the following steps: mixing biomass, a CoOx / ZSM catalyst and a methanol / water mixed solvent, reacting in an H2 atmosphere, extracting a liquid product to obtain 4-n-propyl guaiacol, and separating the CoOx / ZSM catalyst in solid residues to obtain biomass residues. The prepared catalyst does not need precious metal, the reaction condition is mild, the high efficiency and selectivity of the catalyst can be kept in multiple cycles, the ratio of Co to CoO is achieved by regulating and controlling the hydrogen reduction temperature, the hydrogen overflow effect is accurately controlled, and the contradiction among high efficiency, selectivity, mild conditions and cost of a traditional RCF technology is solved.

The invention discloses sweet plum essence and a preparation method thereof. The sweet plum essence is prepared from the following components in parts by mass: 0.01 to 0.05 part of eugenol, 0.02 to 0.10 part of alpha damascenone, 0.05 to 0.20 part of beta damascenone, 0.20 to 1.00 part of guaiacol, 0.20 to 1.00 part of myricetin, 0.30 to 1.50 part of ethyl maltol, 5 to 20 parts of dark plum tincture, 5 to 20 parts of jujube tincture and 50 to 90 parts of propylene glycol. The preparation method comprises the following steps: carrying out clarification pretreatment on dark plum tincture and jujube tincture, dissolving ethyl maltol, eugenol, guaiacol, alpha-damascenone and beta-damascenone in propylene glycol at 35-45 DEG C, cooling to not higher than 30 DEG C, adding myricetin, uniformly mixing, adding a clarified tincture, curing for 12-72 hours, and carrying out 0.22-0.45 mu m microfiltration to obtain a finished product. The obtained essence is clear and stable, good in batch consistency, harmonious in sweet plum style level and lasting in aftertaste, and is suitable for aroma enhancement of foods or beverages.

To provide an animal repellent and an animal repelling method that exhibit a rapid repelling effect against animals and a high sustained repelling effect without olfactory habituation.SOLUTION: The animal repellent contains phenols, such as guaiacol, 3-methoxyphenol, 4-ethylguaiacol, phenol, creosol, o-cresol, m-cresol, and p-cresol as active ingredients.SELECTED DRAWING: Figure 1

A core-shell structured catalyst comprising: a metal nanoparticle, a non-acidic, spherically shaped inner core, and an acid, spherically shaped outer shell, wherein the metal nanoparticle is supported on the spherically shaped inner core. Also disclosed is a method for preparing the core-shell structured catalyst and use thereof for the hydrodeoxygenation of guaiacol to produce an oxygen-free, polycyclic, high-density fuel precursor.

The guaiacol reaction kettle comprises a reaction kettle main body, a stirring device is arranged in the reaction kettle main body, the top end of the reaction kettle main body is connected with a feeding hopper in a penetrating manner, the bottom end of the reaction kettle main body is connected with a discharging pipe in a penetrating manner, an electromagnetic valve is mounted in the discharging pipe, and the electromagnetic valve is connected with the stirring device. The bottom end of the reaction kettle main body is fixedly connected with a base. By arranging the stirring device and the reaction kettle main body, when raw materials are stirred and two stirring assemblies rotate, the raw materials are scattered and stirred, and the raw materials are driven to be pushed in different directions, so that the raw materials are mixed more fully, and the fusion efficiency of the raw materials is greatly improved; and through the arrangement of the scraping plate, the inner wall of the reaction kettle main body is scraped while the scraping plate rotates along the circumference, so that the situation that the raw materials remain on the inner wall of the reaction kettle main body, and then follow-up stirring of the raw materials with different components is influenced is avoided.

The present disclosure provides compositions, methods, and kits for detecting guaiacol-producing microorganisms, in particular, Thermophilic Acidophilic Bacteria (TAB) in foodstuff. In one example, a method comprises: (a) contacting a set of oligonucleotides with the sample, wherein the set of oligonucleotides comprising: a first collection of primers targeted for nucleic acids of a guaiacol-producing microorganism; and a second collection of primers targeted for nucleic acids of Alicyclobacillus acidoterrestris; (b) amplifying DNA in the sample with the said set of oligonucleotides under a multiplex polymerase chain reaction (PCR); and (c) determining the presence of PCR products of step (b), wherein the presence of a PCR product in the sample is indicative of contamination of the sample by both guaiacol-producing microorganism and Alicyclobacillus acidoterrestris.

The present embodiments relate to mixtures, systems, kits and methods useful for detecting strains of the genus Alicyclobacillus that express new genetic variants of the vdcC gene. Alicyclobacillus strains expressing these variants produce guaiacol that results in deterioration of fruit juice products. The methods and mixtures can be used to predict the likelihood of deterioration of fruit juice products contaminated by alicyclic acid bacillus.

This invention discloses a method for the selective hydrogenolysis of lignin using alumina-supported nickel and nickel-tin alloy catalysts to prepare guaiacol monomers. The method employs a urea precipitation method to prepare a catalyst containing both metallic nickel and a nickel-tin alloy active phase. Organosoluble lignin is used as the raw material, and a mixture of alcohols and water is added as the solvent. The alumina-supported nickel and nickel-tin alloy catalyst prepared by the urea precipitation method is then added. The air in the reactor is replaced with an inert gas, and the pressure is increased to 1.0–3.0 MPa. The reactor is then stirred at 210–270°C for 1–6 hours, resulting in the highly selective conversion of organosoluble lignin into compounds primarily composed of guaiacol monomers. This invention features a simple catalyst preparation process, low cost, and a mild and safe lignin depolymerization reaction. The obtained guaiacol products can be used to prepare food additives or pharmaceutical intermediates and other chemicals.

This invention belongs to the field of catalyst preparation technology, and provides a cobalt-gallium alloy catalyst for the hydrodeoxygenation of guaiacol to cyclohexanol, its preparation method, and its application. The preparation method includes the following steps: First, a mixed metal salt solution of cobalt and gallium sources is prepared, then carbon nanotubes are added, and the mixture is ultrasonically dispersed and refluxed. After the reaction, the catalyst is dried and reduced to obtain the catalyst CoGa / CNTs. Then, the CoGa / CNTs are mixed with an organophosphoric acid ligand solution and reacted at room temperature to obtain the organophosphonic acid ligand-modified carbon nanotube supported cobalt-gallium alloy catalyst R-PA@CoGa / CNTs. Applying the prepared catalyst R-PA@CoGa / CNTs to the hydrodeoxygenation of guaiacol to cyclohexanol achieves excellent guaiacol yield under milder reaction conditions and with a lower active metal content.

[Problem] To provide a new fish-attracting composition and fish feed containing the same. [Solution] A fish-attracting composition containing one or more compounds selected from group A.　(Group A) 4-heptenal, 2-nonenal, 2,6-nonadienal, 2,4-decadienal, benzyl alcohol, 1-octanol, 2-ethylhexanol, amyl alcohol, 1-octen-3-ol, ethyl maltol, 2-heptanone, 2-nonanone, 1-octen-3-one, isophorone, homofuraneol, 1,5-octadiene-3-one, cyclotene, γ-butyrolactone, 2-acetyl-3-methylpyrazine, 2,6-dimethoxyphenol, 4-ethylguaiacol, paracresol, 3-ethylphenol, guaiacol, 4-allyl-2,6-dimethoxyphenol, 3-mercapto-2-pentanone

This invention relates to a laccase, its mutants, and their applications, belonging to the field of biotechnology. The amino acid sequence of the laccase PnLac1 is shown in SEQ ID NO.2, and the nucleotide sequence is shown in SEQ ID NO.1. The mutants are site-directed mutations at positions 166 (aspartic acid), 348 (histidine), 403 (methionine), or 467 (leucine) of laccase PnLac1, with amino acid sequences shown in SEQ ID NO.4, 6, 8, and 10, and nucleotide sequences shown in SEQ ID NO.3, 5, 7, and 9. The laccase PnLac1 of this invention achieves a decolorization efficiency of 75% for crystal violet within 5 hours. When ABTS was used as a substrate, the enzyme activities of laccase mutants H348F and L467M increased by 1.89 times and 1.65 times, respectively, showing potential for degrading stubborn substances; when guaiacol was used as a substrate, the enzyme activities of laccase mutants D166A and M403F increased by 2.07 times and 3.72 times, respectively, showing high application prospects in the field of lignin.

The invention relates to the technical field of hydrodeoxygenation of phenolic compounds, in particular to a Co / Ti < 3 > C < 2 > T < x > catalyst and a preparation method and application thereof. The selectivity of the conventional Co / T catalyst for catalyzing hydrodeoxygenation of guaiacol to prepare cyclohexanol is poor, and the selectivity of cyclohexanol is difficult to reach 90% or above. In order to solve the technical problems, the Co / Ti3C2TX catalyst is provided, Co-hcp is loaded on the surface of Ti3C2TX, through strong electron interaction of the Ti3C2TX carrier and Co, excessive deoxidation or cracking reaction is inhibited, efficient directional conversion from phenolic compounds to cyclohexanol is achieved, and in the reaction for preparing cyclohexanol through hydrodeoxygenation of guaiacol, the yield of the catalyst is increased, and the yield of the catalyst is increased. According to the catalyst, the conversion rate of guaiacol reaches 90% or above, the selectivity of the target product cyclohexanol reaches 90% or above, and the catalyst is remarkably superior to a traditional catalyst.

The application discloses a preparation method of vanillin, and steps include: (1) mixing guaiacol, formyl chloride, carbonate and / or bicarbonate and an organic solvent to generate a nucleophilic substitution reaction, and obtaining a reaction solution containing 2-methoxy-1-formic acid benzyl ester; (2) filtering the reaction solution of step (1), and then adding solid superacid to the reaction solution, so that the 2-methoxy-1-formic acid benzyl ester generates a Fries rearrangement reaction under catalysis of the solid superacid to generate vanillin. The method is simple and efficient, has high atom utilization rate, less waste, and the solid superacid can be used as a Fries rearrangement reaction catalyst to improve the selectivity and conversion rate of the reaction, the catalyst is easy to separate and recycle, the catalyst has long service life, the production cost can be effectively reduced, and the production efficiency is improved.