The invention discloses a pressure spring vibration isolation system. The system comprises a panel, an ash blocking sponge, a glass, an upper pressing strip, a liquid crystal screen, an impact gasket,a mounting plate, a lower pressing strip and a vibration isolation device, wherein the two ends of the panel are connected with the upper pressing strip and the lower pressing strip through screws correspondingly; the vibration isolation device is composed of silicon rubber plates, pressure springs and a threaded steel ball spring lock pin; the pressure springs are embedded into the upper pressing strip and the lower pressing strip correspondingly; the silicon rubber plates are embedded into the upper pressing strip and the lower pressing strip correspondingly. According to the pressure spring vibration isolation system, the vibration isolation device is light in weight, and is mainly suitable for a reinforced display which is small in internal space and needs vibration reduction; the design of the vibration isolation device can meet the requirements of high and low temperature, three prevention and the like at the same time; when the vibration isolation device is impacted, the pressure spring reaches the limit, then the liquid crystal screen is in contact with the silicon rubber plates, strong impact can be isolated through the silicon rubber plates, so that good vibration isolation and buffering effects are achieved, an a good vibration isolation effect still good after being impacted, and the pressure can be increased by adjusting the threaded steel ball spring lock pin, so that the damping can be adjusted.