37results about How to "Great efficacy" patented technology

A solid oral controlled-release oral dosage form of hydrocodone is disclosed. The dosage form comprising an analgesically effective amount of hydrocodone or a pharmaceutically acceptable salt thereof, and a sufficient amount of a controlled release material to render the dosage form suitable for twice-a-day administration to a human patient, the dosage form providing a C₁₂/C_max ratio of 0.55 to 0.85, said dosage form providing a therapeutic effect for at least about 12 hours.

The invention features a method for treating a patient diagnosed with, or at risk of developing, an immunoinflammatory disorder by administering a non-steroidal immunophilin-dependent immunosuppressant (NsIDI) and a Group A enhancer (e.g., antifungal agent, antigout agent, anti-infective agent, antiprotozoal agent, antiviral agent, humectant, sunscreen, vitamin D compound, microtubuline inhibitor, or zinc salt) or analog or metabolite thereof to the patient. The invention also features a pharmaceutical composition containing an NsIDI and Group A enhancer or analog or metabolite thereof for the treatment or prevention of an immunoinflammatory disorder.

The invention features a method for treating a patient diagnosed with, or at risk of developing, an immunoinflammatory disorder by administering to the patient an antihistamine, either alone or in combination with one or more additional agents. The invention also features a pharmaceutical composition containing an antihistamine in combination with one or more additional agents.

The invention features methods, compositions, and kits for treating a musculoskeletal disorder, e.g., osteoarthritis, or pain, fatigue, tenderness, impairment in mobility, soft tissue swelling, or bony swelling associated therewith, by administering to a patient diagnosed with or at risk of developing such pain, fatigue, tenderness, impairment in mobility, soft tissue swelling, or bony swelling a tetra-substituted pyrimidopyrimidine, e.g., dipyridamole, or an adenosine activity upregulator, in combination with one or more additional agents. The invention further features methods, compositions, and kits for treating a patient diagnosed with or at risk of developing a musculoskeletal disorder by administering to the patient a tetra-substituted pyrimidopyrimidine or an adenosine activity upregulator in combination with one or more additional agents.

Naltrexone has been used to fight existing infections, afflictions, and substance abuse. Embodiments of the current invention provide naltrexone as a preventative medicine taken daily, usually in the late evening for greater efficacy. It is taken in a low dose like a vitamin supplement and may prevent many diseases by stimulating the immune system. The increased endorphin levels resulting from the use of low dose naltrexone may also reduce the need for pain relief medications, plus counter tendencies toward experiencing undesirable moods, such as depression or anger. Increased feelings of well-being produced by naltrexone may also have far-reaching effects, as suggested by studies showing that people with positive attitudes recover more quickly from serious illnesses, for example. In another aspect of the invention, naltrexone may be used to prevent substance addiction before it ever starts, by blocking the internal positive response that normally results from the use of chemical substances.

A new fertilizer comprising Urea Phosphite, which is made by reacting phosphorous acid with urea. Urea Phosphite is characterized by being a liquid produced in an unprocessed reaction, and by having phosphite as a phosphorus source and urea as a nitrogen source. The reaction product may be blended with an admix and spray dried, or dissolved in water.

Antibody variants originating from the monoclonal antibody 13C6, and wherein the N-glycosylation site within the constant region of the heavy chain contains a glycan that is either wild-type or largely devoid of fucose residues, will bind Ebola virus glycoprotein and provide surprising efficacy in treating animals or humans infected with Ebola virus when used in combination with one or more additional anti-Ebola mAbs. Such antibody cocktails are vastly superior to other known monoclonal antibodies or monoclonal antibody combinations in treating animals and humans infected with the Ebola virus.

The present invention provides compositions, methods, and kits for treating or preventing a viral infection (e.g., an infection caused by an influenza virus).

The invention discloses a pesticide mixer, comprising a mixing box; one side of the mixing box is fixedly connected with a first fixed plate, and the top of the first fixed plate is fixedly connected with a gas pump; an output end of the gas pump is fixedly communicated with a first gas outlet pipe; an exhaust pipe is fixedly communicated with the end, far away from the gas pump, of the first gas outlet pipe; a second gas outlet pipe is fixedly communicated with the side, far away from the first gas outlet pipe, of the exhaust pipe. The pesticide mixer is provided with a pesticide storage tank, so that a pesticide can be stored in advance; when the pesticide flows into the mixing box, the gas pump is started, gas produced by the gas pump is discharged into the mixing box through the first gas outlet pipe, the exhaust pipe and the second gas outlet pipe, and a mixture of water and the pesticide is turned over because of the production of the gas in the mixing box, so that the aim of mixing the water and the pesticide is achieved. By adopting the mixing way, the pesticide is fully mixed, so that the effect of the pesticide is better exerted; furthermore, the pesticide mixer is reasonable in structure and convenient to use.

A humanized convenient door lock includes a lock housing, a latch, a security hook, an outside handle operation mechanism, an inside handle operation mechanism, a cylinder driving mechanism, and an inside deadlocking rotary knob driving mechanism. The inside handle operation mechanism drives and controls the latch, the security hook, and the inside deadlocking rotary knob driving mechanism. To open the door, it only needs a one-time operation by pressing down a handle, thereby providing ease and convenience. The design is a humanized one, making it particularly suit for the needs of the disabled and the elderly and for urgent door opening.

An improved composition of hair oil for stimulation of hair growth, control of hair fall, dandruff and infections thereof. The composition of hair oil comprising active ingredients of Capric Caprylic Tri-Glycerides (CCTG), Mineral oil, Coconut Oil, Ylang Ylang Oil, Di-propylene Glycol, Centella Asiatica Extract and Butylated Hydroxy Toulene. The composition of hair oil supports the hair growth and relaxation of the scalp. The composition of hair oil also effectively reduces/remove dandruff and thereby control hair fall in the subject (e.g., not limiting to male/female human). The composition of hair oil additionally demonstrates the properties of cooling effect, darkening of hair and promotion of hair upon continuous use of the hair oil by the subjects. The proposed composition is alternatively used to reduce/remove Psoriasis.

Antimicrobial compositions derived from edible plant sources such as essential oils, their active components, spices and plant extracts have shown antimicrobial effects against a number of foodborne pathogens. The foodborne pathogens of concern in meat and poultry products include Salmonella enterica, Escherichia coli O157:H7 and Listeria monocytogenes. The antimicrobial compositions were applied to a meat surface using liquid or powder electrostatic spray systems to effectively reduce the amount of pathogens on various meat and poultry products.

A combination of therapeutic agents useful in the treatment of obstructive airways and other inflammatory diseases comprising (i) an adenosine A_2A receptor agonist; and (ii) an anti-cholinergic agent, preferably comprising a member selected from the group consisting of tiotropium and derivatives thereof; the combination being therapeutically effective in the treatment of the diseases when administered by inhalation; as well as to a method of treating the obstructive airways and other inflammatory diseases comprising administering separately, simultaneously or sequentially to the mammal by inhalation a therapeutically effective amount of the combination of therapeutic agents; as well as to a pharmaceutical composition comprising a pharmaceutically acceptable carrier together with the combination of therapeutic agents; as well as to a product containing the compounds of the combination for separate, simultaneous or sequential administration by inhalation to a mammal for the treatment of obstructive airways and other inflammatory diseases. It is preferred that the anti-cholinergic agent component be tiotropium bromide.

The invention discloses a complex pesticide composition containing oxine-copper and thiabendazole. The complex pesticide composition contains active components oxine-copper and thiabendazole, wherein the weight ratio of oxine-copper to thiabendazole is (0.125-8):1. The complex pesticide composition maintains the advantages of little phytotoxicity of oxine-copper and prevention and control effect of thiabendazole on multiple crop diseases; the two pesticide preparations with different action mechanisms synergistically produce optimal pesticide effects, thus the complex pesticide composition has good prevention and control effect, wide disease prevention and control range and low toxicity, and does not tend to generate pesticide resistance. In addition, the mixed preparation is convenient to use, and blending is not needed when a farmer uses the mixed preparation, thereby reducing the labor cost and avoiding excessive use due to improper mixing of the pesticide preparation.

The invention relates to the technical field of traditional Chinese medicines, in particular to an external medicinal liquor for treating soreness, swelling, numbness and pain of body joints and a preparation method thereof, which is characterized in that the external medicinal liquor comprises the following materials in parts by weight: 20-30 parts of cobra, 25-30 parts of garter snake, 20-40 parts of monkshood, 20-40 parts of radix aconiti agrestis, 20-35 parts of artemisia rupestris, 20-38 parts of semen strychni, 20-35 parts of ligusticum wallichii, 15-20 parts of radix curcumae, 20-35 parts of flowers carthami, 200-30 parts of garden balsam stem, 20-30 parts of dried rehamnnia root, and the balance of liquor. The traditional Chinese medicine wine is an external traditional Chinese medicine wine, which is specifically a traditional Chinese medicine formula for treating various arthralgia, neuropathic pain, traumatic injury and numbness of joints caused by qi and blood stasis of a human body due to rheumatism and rheumatoid, and can effectively solve the medication problem of various diseases of the body joints.

The invention provides combination therapy, wherein one or more other therapeutic agents are administered with indibulin or a pharmaceutically acceptable salt thereof and the combination is synergistic. Another aspect of the invention relates to the treatment of cancer with indibulin as a single agent. Another aspect of the invention relates to dosing regimen for administration of oral dosage forms of indibulin.

The stem cells that can be propagated and maintained for extended periods of time in culture in the absence of a feeder layer, and can be used to repair tissue damage. These cells are derived from fetal tissues and are able to repair different types of damage in musculoskeletal system, with significantly greater efficacy than stem cells derived from adult tissues. These cells are hypoimmunogenic and can be used for allogeneic transplantation to vertebrate hosts having disease and/or damage in musculoskeletal and other tissues. The cells can be administered by direct injection to the site in need of repair or by systemic (e.g., intravenous) administration. The stem cells of the invention are capable of migrating to the sites in need of repair, and of adopting a phenotype most appropriate to the nature of the damage, injury or disease.