37results about How to "Great efficacy" patented technology

A solid oral controlled-release oral dosage form of hydrocodone is disclosed. The dosage form comprising an analgesically effective amount of hydrocodone or a pharmaceutically acceptable salt thereof, and a sufficient amount of a controlled release material to render the dosage form suitable for twice-a-day administration to a human patient, the dosage form providing a C12 / Cmax ratio of 0.55 to 0.85, said dosage form providing a therapeutic effect for at least about 12 hours.

The invention features a method for treating a patient diagnosed with, or at risk of developing, an immunoinflammatory disorder by administering a non-steroidal immunophilin-dependent immunosuppressant (NsIDI) and a Group A enhancer (e.g., antifungal agent, antigout agent, anti-infective agent, antiprotozoal agent, antiviral agent, humectant, sunscreen, vitamin D compound, microtubuline inhibitor, or zinc salt) or analog or metabolite thereof to the patient. The invention also features a pharmaceutical composition containing an NsIDI and Group A enhancer or analog or metabolite thereof for the treatment or prevention of an immunoinflammatory disorder.

The invention features a method for treating a patient diagnosed with, or at risk of developing, an immunoinflammatory disorder by administering to the patient an antihistamine, either alone or in combination with one or more additional agents. The invention also features a pharmaceutical composition containing an antihistamine in combination with one or more additional agents.

The invention features methods, compositions, and kits for treating a musculoskeletal disorder, e.g., osteoarthritis, or pain, fatigue, tenderness, impairment in mobility, soft tissue swelling, or bony swelling associated therewith, by administering to a patient diagnosed with or at risk of developing such pain, fatigue, tenderness, impairment in mobility, soft tissue swelling, or bony swelling a tetra-substituted pyrimidopyrimidine, e.g., dipyridamole, or an adenosine activity upregulator, in combination with one or more additional agents. The invention further features methods, compositions, and kits for treating a patient diagnosed with or at risk of developing a musculoskeletal disorder by administering to the patient a tetra-substituted pyrimidopyrimidine or an adenosine activity upregulator in combination with one or more additional agents.

Naltrexone has been used to fight existing infections, afflictions, and substance abuse. Embodiments of the current invention provide naltrexone as a preventative medicine taken daily, usually in the late evening for greater efficacy. It is taken in a low dose like a vitamin supplement and may prevent many diseases by stimulating the immune system. The increased endorphin levels resulting from the use of low dose naltrexone may also reduce the need for pain relief medications, plus counter tendencies toward experiencing undesirable moods, such as depression or anger. Increased feelings of well-being produced by naltrexone may also have far-reaching effects, as suggested by studies showing that people with positive attitudes recover more quickly from serious illnesses, for example. In another aspect of the invention, naltrexone may be used to prevent substance addiction before it ever starts, by blocking the internal positive response that normally results from the use of chemical substances.

A new fertilizer comprising Urea Phosphite, which is made by reacting phosphorous acid with urea. Urea Phosphite is characterized by being a liquid produced in an unprocessed reaction, and by having phosphite as a phosphorus source and urea as a nitrogen source. The reaction product may be blended with an admix and spray dried, or dissolved in water.

The invention relates to a healthcare product, in particular to a tea bag for preventing and treating hypertension, hyperlipidemia and hyperglycemia and a processing method. The tea bag comprises the following components in parts by weight: 20-40 parts of oolong tea, 8-15 parts of mulberry leaves, 8-15 parts of roots of kudzu vine, 8-15 parts of lotus leaves, 8-15 parts of lalang grass rhizome, 5-12 parts of reed rhizome, 5-12 parts of hawthorn, 5-12 parts of white chrysanthemum, 3-10 parts of fried cassia seeds, 3-6 parts of purple perilla, 3-5 parts of watermelon peel, 3-5 parts of orange peel and 1-5 parts of corn stigma. The tea bag has the effects of reducing blood fat, blood sugar and cholesterol and treating stagnation of liver qi, liver-stomach disharmony and the like, and has treatment effects on diseases such as heart and blood vessels, arteriosclerosis, hypertension, hyperlipidemia and hyperglycemia; the raw materials have natural antioxidant functions and comprise various precious trace elements, various vitamins and bioflavonoid substances, so that human body cells can be activated, metabolism of human bodies can be promoted, human body function balance can be regulated, human body health can be maintained, and many magic effects of nourishing stomachs and protecting livers, reducing fat and reducing blood pressure, preventing and treating cancer, and the like can be achieved.

Antibody variants originating from the monoclonal antibody 13C6, and wherein the N-glycosylation site within the constant region of the heavy chain contains a glycan that is either wild-type or largely devoid of fucose residues, will bind Ebola virus glycoprotein and provide surprising efficacy in treating animals or humans infected with Ebola virus when used in combination with one or more additional anti-Ebola mAbs. Such antibody cocktails are vastly superior to other known monoclonal antibodies or monoclonal antibody combinations in treating animals and humans infected with the Ebola virus.

The present invention discloses a silkworm medicine for preventing and curing commonly encountered diseases of silkworm and its preparation method. Said invented medicine preparatino contains (by weight portion) 6-8 portions of carbendazim powder and 2-4 portions of thiophanate-methyl powder. The above-menioned materials can be made into powder dosage form. Also, they can be respectively dissolved in dilute acetic acid and ethyl alcohol so as to obtain liquid dosage form. Said invented medicine is low in toxicity, harmless and pollutionless, and possesses the unique killing action for curing white muscardine, grasserie and others.

The invention belongs to the technical field of cosmetics and particularly relates to cosmetic composition containing plant extracts. The cosmetic composition is mainly sourced from plants, and activecomponents extracted from the plants are natural, green and basically free of toxic and side effects; selected Avena sativa extracts are active substances having different oil-water partition coefficients, different molecular weights and different effects and extracted from different parts of Avena sativa with different extraction techniques; glycosphingolipids and glycolipids from wheat and hydrogenated lecithin from soybeans are selected for nanocrystallizing oil dissolution of Avena sativa active components with a high-pressure microfluidization technique, and transdermal absorption of theactive components is promoted; the cosmetic composition has multiple skin care effects of moisturizing skin, resisting allergy, relieving skin and improving skin barrier functions and is prepared from purified water, polyols, beta-glucan, Avena sativa kernel extract, Avena sativa stem extract, EDTA-2Na, glycosphingolipids, glycolipids, hydrogenated lecithin and Avena sativa kernel oil.

The present invention provides compositions, methods, and kits for treating or preventing a viral infection (e.g., an infection caused by an influenza virus).

The invention discloses a pesticide mixer, comprising a mixing box; one side of the mixing box is fixedly connected with a first fixed plate, and the top of the first fixed plate is fixedly connected with a gas pump; an output end of the gas pump is fixedly communicated with a first gas outlet pipe; an exhaust pipe is fixedly communicated with the end, far away from the gas pump, of the first gas outlet pipe; a second gas outlet pipe is fixedly communicated with the side, far away from the first gas outlet pipe, of the exhaust pipe. The pesticide mixer is provided with a pesticide storage tank, so that a pesticide can be stored in advance; when the pesticide flows into the mixing box, the gas pump is started, gas produced by the gas pump is discharged into the mixing box through the first gas outlet pipe, the exhaust pipe and the second gas outlet pipe, and a mixture of water and the pesticide is turned over because of the production of the gas in the mixing box, so that the aim of mixing the water and the pesticide is achieved. By adopting the mixing way, the pesticide is fully mixed, so that the effect of the pesticide is better exerted; furthermore, the pesticide mixer is reasonable in structure and convenient to use.

A humanized convenient door lock includes a lock housing, a latch, a security hook, an outside handle operation mechanism, an inside handle operation mechanism, a cylinder driving mechanism, and an inside deadlocking rotary knob driving mechanism. The inside handle operation mechanism drives and controls the latch, the security hook, and the inside deadlocking rotary knob driving mechanism. To open the door, it only needs a one-time operation by pressing down a handle, thereby providing ease and convenience. The design is a humanized one, making it particularly suit for the needs of the disabled and the elderly and for urgent door opening.

An improved composition of hair oil for stimulation of hair growth, control of hair fall, dandruff and infections thereof. The composition of hair oil comprising active ingredients of Capric Caprylic Tri-Glycerides (CCTG), Mineral oil, Coconut Oil, Ylang Ylang Oil, Di-propylene Glycol, Centella Asiatica Extract and Butylated Hydroxy Toulene. The composition of hair oil supports the hair growth and relaxation of the scalp. The composition of hair oil also effectively reduces / remove dandruff and thereby control hair fall in the subject (e.g., not limiting to male / female human). The composition of hair oil additionally demonstrates the properties of cooling effect, darkening of hair and promotion of hair upon continuous use of the hair oil by the subjects. The proposed composition is alternatively used to reduce / remove Psoriasis.

Antimicrobial compositions derived from edible plant sources such as essential oils, their active components, spices and plant extracts have shown antimicrobial effects against a number of foodborne pathogens. The foodborne pathogens of concern in meat and poultry products include Salmonella enterica, Escherichia coli O157:H7 and Listeria monocytogenes. The antimicrobial compositions were applied to a meat surface using liquid or powder electrostatic spray systems to effectively reduce the amount of pathogens on various meat and poultry products.

The invention belongs to the field of biological fertilizers, and in particular discloses a selenium enriched plant extract composite film forming regulator and a preparation method thereof. The selenium enriched plant extract composite film forming regulator mainly includes an inorganic fertilizer, an organic fertilizer and a microbial fertilizer. The selenium enriched plant extract composite film forming regulator comprises the following components: 30-60 parts of an inorganic fertilizer, 10-15 parts of Rhizoma Bletillae, 10-15 parts of garden burnet, 5-10 parts of catechu, 5-15 parts of Coptis chinensis, 15-25 parts of polyvinyl alcohol, 20-25 parts of sodium carboxymethylcellulose and 0.5-1.5 parts of Na2SeO3. The selenium enriched plant extract composite film forming regulator can improve the soil structure, has a wide application range, and can effectively improve the survival rate of seedling-forming-period crops; by organic combination and interaction of pepper, tobacco leaf, allicin, dongguo, mint and the like, the drug effect of the pesticide composition can be played to the largest degree, raw materials are relatively easy to get, production cost is low, development of resistance is delayed, and the service life is prolonged.

The invention belongs to the technical field of toothpaste production and particularly relates to a GUF radix-glycyrrhizae-active-component composition and GUF radix glycyrrhizae toothpaste containingthe same. The GUF radix-glycyrrhizae-active-component composition is compounded by dipotassium glycyrrhizinate, ammonium glycyrrhizinate, disodium glycyrrhizinate, stearyl glycyrrhetinate according to the mass ratio of (0.5-1):(0.5-1):(0.1-1):(0.1-1). The GUF radix glycyrrhizae toothpaste comprises, by weight, 0.01-10 parts of GUF radix-glycyrrhizae-active-component composition, 30-80 parts of moisturizing agent, 10-30 parts of abrasive, 0.1-10 parts of foaming agent, 0.1-15 parts of thickening agent, 0-2 parts of aromatic, 0-1 part of pH buffer agent and 0-0.2 part of pigment. By reasonablematerial combination, the GUF radix glycyrrhizae toothpaste containing the GUF radix-glycyrrhizae-active-component composition has healthcare functions of eliminating oral inflammation and inhibitingoral bacteria.

A combination of therapeutic agents useful in the treatment of obstructive airways and other inflammatory diseases comprising (i) an adenosine A2A receptor agonist; and (ii) an anti-cholinergic agent, preferably comprising a member selected from the group consisting of tiotropium and derivatives thereof; the combination being therapeutically effective in the treatment of the diseases when administered by inhalation; as well as to a method of treating the obstructive airways and other inflammatory diseases comprising administering separately, simultaneously or sequentially to the mammal by inhalation a therapeutically effective amount of the combination of therapeutic agents; as well as to a pharmaceutical composition comprising a pharmaceutically acceptable carrier together with the combination of therapeutic agents; as well as to a product containing the compounds of the combination for separate, simultaneous or sequential administration by inhalation to a mammal for the treatment of obstructive airways and other inflammatory diseases. It is preferred that the anti-cholinergic agent component be tiotropium bromide.

The invention discloses a complex pesticide composition containing oxine-copper and thiabendazole. The complex pesticide composition contains active components oxine-copper and thiabendazole, wherein the weight ratio of oxine-copper to thiabendazole is (0.125-8):1. The complex pesticide composition maintains the advantages of little phytotoxicity of oxine-copper and prevention and control effect of thiabendazole on multiple crop diseases; the two pesticide preparations with different action mechanisms synergistically produce optimal pesticide effects, thus the complex pesticide composition has good prevention and control effect, wide disease prevention and control range and low toxicity, and does not tend to generate pesticide resistance. In addition, the mixed preparation is convenient to use, and blending is not needed when a farmer uses the mixed preparation, thereby reducing the labor cost and avoiding excessive use due to improper mixing of the pesticide preparation.

The invention discloses a micromolecular kelp beverage and a preparation method thereof. The micromolecular kelp beverage is characterized in that kelp, soybean, Chinese flowering quince, apples, strawberries, mulberry leaves, perilla leaves and ginger are used as raw materials; the micromolecular kelp beverage is prepared through the technology steps of performing preprocessing, performing cleaning, performing mincing, performing defibrination, performing homogenization, performing heating and ultrasonic processing, performing filtration, performing homogenizing, performing deaeration, performing filling and sealing, performing microwave sterilization and performing packaging. The micromolecular kelp beverage disclosed by the invention uses the kelp as main raw materials and selects specific medicinal and edible auxiliary materials for scientific concerted application so that the beverage with the characteristics of high nature, high efficiency, high convenience, high safety and the like is prepared, the nutrient components and the bioactivity of the raw materials of each component are perfectly reserved, the micromolecular kelp beverage is convenient to eat and easy to absorb by a human body, the nutrition efficacy of the kelp is promoted, the abuse of a tradition processing method is eliminated, and the micromolecular kelp beverage has remarkable nutrition and health-care effects on the human body.

The invention relates to the technical field of traditional Chinese medicines, in particular to an external medicinal liquor for treating soreness, swelling, numbness and pain of body joints and a preparation method thereof, which is characterized in that the external medicinal liquor comprises the following materials in parts by weight: 20-30 parts of cobra, 25-30 parts of garter snake, 20-40 parts of monkshood, 20-40 parts of radix aconiti agrestis, 20-35 parts of artemisia rupestris, 20-38 parts of semen strychni, 20-35 parts of ligusticum wallichii, 15-20 parts of radix curcumae, 20-35 parts of flowers carthami, 200-30 parts of garden balsam stem, 20-30 parts of dried rehamnnia root, and the balance of liquor. The traditional Chinese medicine wine is an external traditional Chinese medicine wine, which is specifically a traditional Chinese medicine formula for treating various arthralgia, neuropathic pain, traumatic injury and numbness of joints caused by qi and blood stasis of a human body due to rheumatism and rheumatoid, and can effectively solve the medication problem of various diseases of the body joints.

The invention provides combination therapy, wherein one or more other therapeutic agents are administered with indibulin or a pharmaceutically acceptable salt thereof and the combination is synergistic. Another aspect of the invention relates to the treatment of cancer with indibulin as a single agent. Another aspect of the invention relates to dosing regimen for administration of oral dosage forms of indibulin.

The invention relates to a toothpaste, in particular to a medicated toothpaste. A paste body of the medicated toothpaste contains erigeron breviscapus extract. The erigeron breviscapus extract accounts for 0.1-25% by weight of the paste body of the medicated toothpaste, the preferential weight ratio is 0.5-10%, and the optimal weight ratio is 1-5%. The erigeron breviscapus extract is dry powder of ethanol extract or the dry powder of the extract obtained by the water decoction method. The application of the medicated toothpaste has the following benefits: the medicated toothpaste has extensive efficacy and obvious effects of eliminating inflammation, relieving pain and preventing periodontitis, gingivitis, halitosis, saprodontia and oral ulcers, and is simultaneously particularly applicable to people groups with high risk of having cerebrovascular diseases and the like; in addition, the cost is low, and erigeron breviscapus has the characteristics of extensive distribution and cheap price, thereby being capable of effectively reducing the cost of producing the medicated toothpaste.

The invention belongs to the technical field of cosmetics and particularly relates to cosmetic composition containing plant extracts. The cosmetic composition is mainly sourced from plants, and activecomponents extracted from the plants are natural, green and basically free of toxic and side effects; selected Avena sativa extracts are active substances having different oil-water partition coefficients, different molecular weights and different effects and extracted from different parts of Avena sativa with different extraction techniques; glycosphingolipids and glycolipids from wheat and hydrogenated lecithin from soybeans are selected for nanocrystallizing oil dissolution of Avena sativa active components with a high-pressure microfluidization technique, and transdermal absorption of theactive components is promoted; the cosmetic composition has multiple skin care effects of moisturizing skin, resisting allergy, relieving skin and improving skin barrier functions and is prepared from purified water, polyols, beta-glucan, Avena sativa kernel extract, Avena sativa stem extract, EDTA-2Na, glycosphingolipids, glycolipids, hydrogenated lecithin and Avena sativa kernel oil.

The invention belongs to the technical field of toothpaste production, and specifically relates to a GUF licorice active ingredient composition and a GUF licorice toothpaste containing the composition. The GUF licorice active ingredient composition of the present invention consists of dipotassium glycyrrhizinate, ammonium glycyrrhizinate, Sodium and stearyl glycyrrhetinate are compounded by mass ratio (0.5-1): (0.5-1): (0.1-1): (0.1-1), and GUF licorice toothpaste of the present invention consists of the following weight Raw material composition: 0.01-10 parts of GUF licorice active ingredient composition, 30-80 parts of moisturizing agent, 10-30 parts of friction agent, 0.1-10 parts of foaming agent, 0.1-15 parts of thickener, 0-2 parts of fragrance 0-1 part of pH buffer and 0-0.2 part of pigment. The toothpaste containing the GUF licorice active ingredient composition of the invention has the health care function of eliminating oral inflammation and inhibiting oral bacteria through reasonable compatibility.

The stem cells that can be propagated and maintained for extended periods of time in culture in the absence of a feeder layer, and can be used to repair tissue damage. These cells are derived from fetal tissues and are able to repair different types of damage in musculoskeletal system, with significantly greater efficacy than stem cells derived from adult tissues. These cells are hypoimmunogenic and can be used for allogeneic transplantation to vertebrate hosts having disease and / or damage in musculoskeletal and other tissues. The cells can be administered by direct injection to the site in need of repair or by systemic (e.g., intravenous) administration. The stem cells of the invention are capable of migrating to the sites in need of repair, and of adopting a phenotype most appropriate to the nature of the damage, injury or disease.

The invention discloses multi-taste peanut crisps with a health preserving effect and a production process of the multi-taste peanut crisps. The peanut crisp is prepared from the following raw materials in parts by weight: 280-560 parts of edible oil, 1-2 parts of eggs, 5-10 parts of baking powder, 2-4 parts of baking soda, 1-2 parts of salt, 380-760 parts of flour, 50-100 parts of sugar, 100-200parts of walnut kernels, 100-200 parts of peanut kernels, 15-30 parts of Chinese wolfberry and 10-20 parts of auxiliary materials. According to the multi-taste peanut crisps with the health preservingeffect and the production process of the multi-taste peanut crisps, Chinese wolfberry and walnut kernels are added into the peanut crisps, so that nutritional ingredients are enhanced, the flavor, taste and health preserving effect of the peanut crisps are improved through the auxiliary materials; the auxiliary materials comprise osmanthus fragrans, vanilla, lemon leaves, gingko, gardenia jasminoides, lavender, Chinese rose and ligustrum lucidum, a manufacturer can select one of the auxiliary materials according to market requirements to change the fragrance, taste and health preserving effect of the peanut crisps, a client can select the favorite peanut crisp according to his / her favorite, the health preserving effect is very good, and the making is simple.

The invention provides a road grade integrated repairing device to be repaired which can prevent unhooking, and belongs to the technical field of road grade repair. The road grade integrated repairingdevice to be repaired comprises a collecting box, an opening-closing plate, a hinge track, an articulator, a support post, a sliding groove, a main rotating shaft, a rotary table, sliding grooves, ahydraulic rod, a movable support post, an auxiliary rotating shaft, a clamping groove, a clamping groove II, a top rod, a sliding plate, a clamping nail, an occlusion nail, a spring, a suction foldingpipe, a motor, a rotating structure, a rotating arm, a motor, a gear, a rotating arm II and a material discharge folding pipe, wherein the surface of the top of the collecting box is movably connected with the opening-closing plate, the front end and the rear end of the left surface of the collecting box are fixedly connected with the hinge track, one side surface of the hinge track is movably connected with the articulator, the articulator is connected with the hinge track in a sliding manner, the left side surface of the articulator is fixedly connected with the support post, the surfaces of the front end and the rear end of the support post are provided with sliding grooves in a nested manner, the inner surface of the articulator is fixedly connected with the main rotating shaft, the outer surface of the main rotating shaft is provided with a rotating disc in a penetrating way, and one side of the rotating disc is provided with the sliding groove in a nested manner.

A hypertonic emulsified rotenone oil as agricultural chemical is prepared through such technological steps as adding raw rotenone (1-5 portions) to reactor, adding CT-901 penetrant (10-14 portions) and xylene (68-69 portions), raising temp to 50-60 deg.C, stirring, adding NPE-90 penetrating aid (2.5-3.5 portions) and 0208 anionic surfactant (8-10 portions) and stirring. Its advantages are high effect, no residual damage, quickly taking its effect, not generating resistance easily for pests and broad spectrum, especially preventing insect pest such as bollworm, red spider.

The present invention discloses a silkworm medicine for preventing and curing commonly encountered diseases of silkworm and its preparation method. Said invented medicine preparatino contains (by weight portion) 6-8 portions of carbendazim powder and 2-4 portions of thiophanate-methyl powder. The above-menioned materials can be made into powder dosage form. Also, they can be respectively dissolved in dilute acetic acid and ethyl alcohol so as to obtain liquid dosage form. Said invented medicine is low in toxicity, harmless and pollutionless, and possesses the unique killing action for curing white muscardine, grasserie and others.