The invention provides a full-period construction method for a flexible reserved floor high-rise building and vehicle depot structure. The method comprises the following steps of Step 1, constructing a first-stage structure: Step 11, constructing a plurality of building pile foundations and a first-stage raft plate; Step 12, constructing a vehicle depot large garage; Step 13, constructing a retaining wall; and Step 14, building brick partition walls after construction; and Step 2, constructing a second-stage structure: Step 21, constructing a second-stage raft plate and a shear wall of the high-rise building; Step 22, constructing a car garage and the remaining shear walls, and constructing the high-rise building; and Step 23, constructing a second-stage cover plate, performing soil covering, then performing greening till the construction is completed. The full-period construction method of the structure comprises a structure reservation scheme for flexibly adjusting the house type of the floor high-rise building and a construction scheme for the later-stage high-rise building, the house type of the later-stage high-rise building can be flexibly adjusted, and the height of the high-rise building is not limited by a conversion structure.