The invention relates to a system and a method for trajectory tracking during circulation of an E-mail. The method includes: when a sender sends an E-mail, a unique identifier is generated for each receiver, and the receiver accesses the E-mail theme through the unique identifier; when each receiver's operation on the E-mail is detected, the operation trajectory is fed back to the sender; after the information feedback, the sender can accurately learn about whether the corresponding receiver reads the E-mail or not, whether the corresponding receiver forward the E-mail or not, whether the corresponding receiver download an attachment or not, whether the corresponding receiver print the attachment or not, whether the corresponding receiver edit the attachment or not, E-mail reading times, E-mail reading time, E-mail forwarding times, E-mail forwarding time, who the E-mail is forwarded to, attachment reading times, attachment reading time, attachment downloading times, attachment downloading time, attachment editing times, attachment editing time, attachment printing times, attachment printing time and the like. By the method, comprehensive E-mail trajectory tracking can be performed, and E-mail transmitting efficiency and safety are increased by the information feedback.