The invention relates to the technical field of woodworking machinery, in particular to a single-spindle woodworking milling machine with a high-speed spindle. The milling machine comprises a machine frame, a workbench, a milling cutter device, a milling cutter lifting device and a motor, wherein the workbench and the machine frame are fixedly connected; a control device is arranged on the machine frame; the milling cutter device comprises a spindle, a milling cutter, a cutter assembling nut, a flat hole sleeve and a cutter pressing screw; and the milling cutter lifting device is composed of a lifting screw, a sliding plate, a sliding plate base, a lifting hand wheel, a lifting nut, a locking device, a worm gear, a worm, a bearing and a bearing base. The milling machine is characterized in that the shaft of the motor extends and is connected with the spindle into a whole; the lower end of the cutter assembling nut is fixedly connected with an upper end cover of the motor; the motor and the sliding plate are fixedly connected; the milling cutter is directly driven by the motor; and parts, such as a motor plate, a transmission belt, a motor wheel, a spindle wheel and the like, are saved, thus the manufacturing cost of a machine tool is effectively lowered, the integral performance of the machine tool is steady, the power consumption of the motor is reduced, and the milling machine is steady to operate.