The invention provides a full negative pressure short wall filling coal mining method. The full negative pressure short wall filling coal mining method comprises the following steps that 10, positionsof a centralized return air lane and a centralized transportation lane are determined, and a transportation roadway, a first return air roadway and a second return air roadway are arranged; 20, tunneling is carried out on a branch lane in a first mining area, and after the branch lane is penetrated, tunneling is carried out on a branch lane in a second mining area, at the same time, supporting iscarried out on a penetrated branch lane, and a communication port between the penetrated branch lane and the transportation roadway is blocked; 30, the penetrated branch lane is filled after pluggingis finished; 40, tunneling is carried out on another branch lane in the first mining area, at the same time, supporting is carried out on a penetrated branch lane in the second mining area and a communication port between the penetrated branch lane and the transportation roadway is blocked; 50, the penetrated branch lane in the second mining area is filled after plugging is finished; 60, steps 10to 50 are cycled until the branch lane is completely filled; and 70, after filling is completed, reserved coal pillar lanes are successively mined according to the direction from the far end to the near end.