The invention discloses a scale full-artificial-breeding method for sepiella maindroni. The scale full-artificial-breeding method comprises five steps, such as selection of breeding mode, cleaning and sterilizing before
offspring seeds feeding, transporting and
stocking of the
offspring seeds, breeding management as well as harvesting and transporting. The scale full-artificial-breeding method comprises the specific steps of: breeding in selective
seawater net cage, pond or indoor
cement pit and cleaning and sterilizing before
offspring seeds feeding; oxygenating and transporting the offspring seeds by using
polyethylene plastic bags, controlling the temperature and the
salinity and feeding the offspring seeds and controlling the
stocking density; controlling parameters such as the temperature, the
salinity, the pH values and the like during breeding management; regulating and controlling the
water quality, feeding small fish shrimps captured from the sea as feed; controlling the feeding amount and the feeding time and preventing diseases; breeding for 3-4 months and stopping feeding for one day before harvesting; and transporting by adopting a flowing
water vehicle. The scale full-artificial-breeding method is suitable for the scale full-artificial-breeding operation of the sepiella maindroni and has the advantages of
high survival rate, fewer diseases, easiness for breeding,strong
disease resistance, high
growth speed and the like. In addition, the scale full-artificial-breeding method is easy for implementation and operation, is high in
survival rate and is suitable for large-scale popularization.