The invention relates to a production method of a craft picture by utilizing natural river stones. The production method comprises the following steps: designing patterns; selecting a hard soleplate, and selecting raw stones, sand and stone powder, which are matched with the patterns, from a river; washing the selected stones by utilizing clean water, and screening the stones; directly drawing the design drawing on a soleplate by the hand, or printing the design drawing on the soleplate by virtue of a piece of carbon paper, or cutting paper into pieces shaped like the patterns in the design drawing, and pasting the paper pieces onto the soleplate; preparing transparent glue; drawing the outline of the patterns which are drawn by the hand on the soleplate by utilizing glue, or drawing the outlines of the patterns which are printed on the soleplate by utilizing the glue, or drawing the outlines of lines of the patterns on the soleplate by utilizing the glue, removing the paper pieces, and fully coating the patterns with the glue; adhering stone sand, stone powder and/or raw stones on the patterns; washing a combined picture by utilizing an abstergent; and coating the surface of the combined picture with varnish to obtain the craft picture. Compared with the prior art, for the production method, the three-dimensional effect of the picture is embodied by reasonably combining the river stones, the sand and the stone powder. The craft picture is attractive, firm, fadeless, difficult to drop and convenient to store.