The invention discloses a vacuum pressure impregnation system, comprising: a pressure impregnation tank, a circulating water tank, a liquid medicine pool, a centrifugal pump, a vacuum pump, a pressure pump, a suction and discharge valve, a partial pressure pump, a pressure gauge, a vacuum gauge, and a press; The circulating water tank is fixedly connected to the centrifugal pump and the vacuum pump, the centrifugal pump is connected to the empty pump, the centrifugal pump is connected to the vacuum gauge, the vacuum gauge is connected to the pressure gauge, the pressure gauge is connected to the pressure dipping tank, and the pressure gauge is connected to the press machine. The partial pressure pump is fixedly connected to the pressure dipping tank, and the partial pressure pump is fixedly connected to the liquid medicine pool; the pressure dipping tank is fixedly connected to the booster pump, and the booster pump is fixedly connected to the liquid medicine pool. Pool fixed connection. The vacuum pressure impregnation of the present invention can not only make the modifying agent enter the deeper part of the material in a short time, but also can use the size of the pressure and vacuum to adjust the entering depth and amount, adapt to different requirements of material property changes, and improve processing efficiency and control costs.