The invention provides a large-scale numerical control gear machining machine tool which has six numerical control coordinate axes, namely X, Y, Z, A, C1 and C2 and adopts a two plus four layout manner. A workpiece has two freedom motion, namely linear motion along the X axis and rotational motion around the C1 axis; and a tool has four freedom motion, namely linear motion along the X axis and the Z axis and rotational motion around the A axis and the C2 axis. The large-scale numerical control gear machining machine tool adopts a six-axis (X, Y, Z, A, CI and C2 axis) five-linkage (X, Y, Z, A and C2 axis linkage) structure; the five numerical control coordinate axes, namely the X, Y, Z, A and C2 axes carry out interpolation motion; and the indexing movement of the workpiece is controlled by the C1 axis to process all tooth surfaces. The rotational axis of the workpiece, namely the C1 axis only finishes the indexing movement and does not participate in the interpolation motion formed bythe tooth surfaces so as to improve the processing precision and the processing efficiency of a large-scale gear. The large-scale numerical control gear machining machine tool can be constructed intoa gear miller or a gear grinder, thereby realizing the curved surface machining of a cylindrical gear, a bevel gear, an impeller and others with the indexing features.