The invention provides a machine room fire-fighting information comprehensive linkage scheduling system and method, which aim at the bottleneck of the traditional fire-fighting technology, are designed through three aspects of environment data intelligent acquisition, data intelligent analysis and power equipment intelligent control, acquire the temperature and humidity, smoke, flame, far infrared heat release signals, electrical load and AI images of a machine room, perform calculation and analysis, discriminate abnormal data through multi-dimensional information comprehensive analysis, and control an air conditioner, a ventilation system, a fireproof door fire extinguisher and a power switch control module according to data linkage. The problems of inaccurate alarm data, untimely alarm data and the like caused by multiple factors such as single environment acquisition data, no data analysis algorithm, incapability of controlling power equipment and the like in traditional fire fighting equipment are solved. Meanwhile, through artificial intelligence analysis, prediction and alarm of potential risks are achieved, power equipment is regulated and controlled, and fire accidents are avoided.