The invention discloses a sorting screen of a combine harvester, which comprises a screen body, an eccentric drive mechanism and sliding mechanisms, wherein the eccentric drive mechanism is disposed below one end of a screen body, and the sliding mechanisms are symmetrically disposed on two sides of the other end of the screen body. The screen body comprises a screen frame, an upper mesh screen, a lower mesh screen, a corrugated plate and a plurality of sorting baffles. The eccentric drive mechanism comprises a crankshaft, a pair of connecting plates and a pair bearing blocks, wherein two ends of the crankshaft are supported inside the bearing blocks through bearings respectively, a crankshaft journal is fixedly respectively connected with the lower end of every one of the connecting plates in one pair, and the upper ends of the connecting plates in one pair are fixedly connected with the front bottom and the rear bottom of the screen frame respectively. The sliding mechanisms comprise sliding seats and rollers, wherein the rollers supported at the front and the rear of the screen frame are inlaid inside the sliding seats. The sorting screen is simple and compact in structure, threshed grains fall onto the whole screen surface and flow from the left to the right, and the left and the right of the screen are evenly stressed so that the screen is less prone to damage. The screen is small in size and large in sorting area, so that the overall weight of the harvester is lowered greatly, the overall reliability of the harvester is improved, and the grains are sorted effectively and efficiently.