50results about How to "Treatment effect" patented technology

Methods and devices for measuring the size of a body lumen and a method for ablating tissue that uses the measurement to normalize delivery of ablational energy from an expandable operative element to a luminal target of varying circumference are provided. The method includes inserting into the lumen an expandable operative element having circuitry with resistivity or inductance that varies according to the circumference of the operative element, varying the expansion of the operative element with an expansion medium, measuring the resistivity of the circuitry, and relating the resistivity or inductance to a value for the circumference of the operative element. In some embodiments the sizing circuit includes a conductive elastomer wrapped around the operative element. Other embodiments of the method apply to operative elements that include an overlapping energy delivery element support in which the overlap varies inversely with respect to the state of expansion, and which is configured with sizing electrodes that sense the amount of the overlap.

A transdermal drug administration system with microneedles which can perforate the skin (stratum corneum) by a simple operation at the time of transdermal administration of a physiologically active substance (drug) is provided.

The present transdermal drug administration system with microneedles comprises microneedle device (50) having a plurality of microneedles (51) which can perforate the skin and a plurality of solution passages (52); absorbent (11) which is disposed on microneedle device (50), comprising dried drug (10) and a material which can absorb liquid; and dissolution liquid reservoir (18) which is disposed on absorbent (11) and stores dissolution liquid (16) for dissolving drug (10) and in which a diaphragm (20) provided between absorbent (11) can be broken by pressing. Dissolution liquid reservoir (18) is pressed to break diaphragm (20), and at the same time, the microneedle (51) perforates the skin (stratum corneum), and drug (10) dissolved in dissolution liquid (16) is transmitted through microneedle device (50) to the skin.

The present invention concerns methods and compositions for the treatment of cancer and cancer cells using altered poxviruses, including a vaccinia virus that has been altered to generate a more effective therapeutic agent. Such poxviruses are engineered to be attenuated or weakened in their ability to affect normal cells. In some embodiments, methods and compositions involve poxviruses that possess mutations that result in poxviruses with diminished or eliminated capability to implement an antiviral response in a host. Poxviruses with these mutations in combination with other mutations can be employed for more effective treatment of cancer.

A method of connecting a terminal fitting and an electric wire, includes the steps of: providing a terminal fitting; providing an electric wire in which a core wire is covered with an insulating sheath; providing a conductive connecting member formed with an insertion hole; inserting the electric wire into the insertion hole of the connecting member; compressing the connecting member radially inwardly so as to caulk an inserted portion of the electric wire uniformly over a whole periphery thereof; and welding the connecting member and the terminal fitting by applying ultrasonic wave.

The present invention encompasses methods and compositions for generating a biomimetic proteoglycan. The invention includes methods of treating a disease, disorder, or condition of soft tissue using a biomimetic proteoglycan.

A process of removing SO₂ from a flue gas with a trickling filter using modified ceramsite packing is described. The biological flue gas desulfurization process includes: feeding the flue gas containing sulfur dioxide through the column bottom into the biomembrane trickling filter at certain temperature, contacting with the modified ceramsite biomembrane packing and purifying, which purified flue gas is discharged via the column top; and spraying the nutrient fluid rich in high concentration of the desulfurization strain through the top to the modified ceramsite biomembrane packing, thereby the sulfur-bearing pollution source in the flue gas is degraded, so as to discharge a purified flue gas satisfying the environmental requirements.

The present disclosure provides compounds and methods of use thereof for treating inflammatory diseases or disorders.

The present invention describes a method of treating individuals suffering from microbial infections, including a parasitic disease such as malaria, by using an improved Artemisinin Combination Therapy, known as Tri-ACT. The improved ACT therapy includes administering a combination of three drugs. In one embodiment of the present invention, the method includes administering to an individual a first composition comprising a therapeutically effective amount of an artemether spray sublingually. The individual is then administered a second composition, a therapeutically effective amount of artesunate. A third composition, an effective amount of berberine, or its pharmaceutically acceptable derivatives or salts is administered to the individual.

A topical formulation for application to exposed body tissue, the formulation comprising a silver(II) oxide and zinc oxide, intimately dispersed within a carrier medium.

The present invention provides compounds useful for increasing cellular ATP binding cassette transporter ABCA1 production in mammals, and to methods of using such compounds in the treatment of coronary artery diseases, dyslipidiemias and metabolic syndrome. The invention also relates to methods for the preparation of such compounds, and to pharmaceutical compositions containing them.

Disclosed is a medicine for treating fatty liver which is prepared from root of herbaceous peony, oriental water plantain rhizome, polyporus umbellatus, poria cocos, oriental wormwood, talcum powder, donkey-hide gelatin, fructus garedeniae, rhubarb horsetails and coix seed. The medicament is prepared into the form of granular powder with the advantages of good taste and easy administering.

Interleukin-15 muteins and other interleukin-15-related molecules are described, as well as methods of identifying interleukin-15 muteins and other interleukin-15-related molecules. Also described herein are modifications of the foregoing, which modifications may enhance a property (e.g., half-life) of the muteins or other molecules compared to human interleukin-15. Pharmaceutical compositions and methods of use are also described herein.

The invention discloses a suppository for treating vaginitis, which comprises the following components in ratio by weight: 0.001 to 0.02 percent of musk, 5 to 15 percent of radix polygalae, 15 to 25 percent of psoralea, 15 to 25 percent of rhubarb, and 45 to 50 percent of glycerin fatty acid ester. The invention also discloses a method for preparing the suppository for treating the vaginitis. The invention further discloses a method for using the suppository for treating the vaginitis. The suppository for treating the vaginitis clears away heat and toxic materials, kills insects and relieves itching, and mainly treats trichomonas vaginitis with remarkable effect.

A compound of formula (I)

wherein A, R¹, R³, and R²⁴ are described herein. The compounds are useful as inhibitors of potassium channel function and in the treatment and prevention of arrhythmia, I_Kur-associated disorders, and other disorders mediated by ion channel function.

Methods are provided for using antibodies that bind one or more cysteinyl leukotrienes (cysLTs) for treatment of diseases, including inflammatory diseases and asthma, associated with aberrant levels of one or more cysLTs. Anti-cysLT antibodies and antigen-binding antibody fragments, and compositions containing such antibodies and antibody fragments, are also provided.

The invention relates to methods for inducing marrow stromal cells to differentiate into neural cells by way of increasing intracellular levels of cyclic AMP. The invention also encompasses methods of producing a neural cell by causing a marrow stromal cell to differentiate into a neural cell by increasing intracellular levels of cyclic AMP. Methods for treating a human patient in need of neural cells are also disclosed, as well as methods for treating a human patient having a disease, condition, or disorder of the central nervous system.

The invention provides a slice electrode which is small, exquisite and reasonable in shape design, convenient to use and multiple in function. The thickness of the slice electrode is only 2mm, and the slice electrode is of a lampshade-type shape and is formed by electrode slices and wire ports. Conducting strips, insulating strips and a heating device are arranged in a slice electrode body and connected with wires on the outside, a temperature sensor is installed between the insulating strips and the conducting strips, and the two ends of the temperature sensor are connected with a terminal through wires; the inner side of the slice electrode body is provided with heat dissipation overlapping curves which have a temperature control function and are capable of fully emitting local heat so that the slice electrode can be more convenient, more comfortable and safer to use. In the mastopathy treating process, the slice electrode can be directly put into a bra for treatment next to the skin; adjustable diagnosis models of electrical stimulation include high-frequency waves, acupuncture waves, sparse waves, fluctuant waves, discontinuous waves, audio waves and fluctuant and discontinuous waves; different therapeutic schedules can be set according to different symptoms, and the medical multi-function slice electrode has remarkable curative effects especially on female mastopathy.

The invention provides a medicament for curing chronic aplastic anemia and a preparation method thereof. The medicament is prepared by the following raw materials: purple beautyberry, notoginseng, ginseng, wolfberry fruit, donkey-hide gelatin beads, Chinese caterpillar fungus, prepared rehmannia root, white atractylodes rhizome, dogwood fruit, rhizoma discoreae, Chinese angelica, honey, and the like, and according to the characteristics of different tastes, channel tropism, function and principle indications of all the Chinese medicinal herbs, the Chinese medicinal herbs are respectively screened, processed according to the weight (portion) proportion, dried, crushed, melted, evenly mixed and milled into honeyed pills, and the sterilization and the packaging by vacuum film pressing are performed to the honeyed pills. The medicament has good effect for curing the chronic aplastic anemia, is convenient to safely and efficiently take by patients who do not need to suffer from blood transfusion and bone morrow transplantation and take hormone medicine, has low treatment cost, and the like.

The invention discloses a method for rapidly preparing and screening candida albicans-resistant medicines with an unsaturated fatty acid structure. A structure of an analogue or a derivative of a class of the candida albicans-resistant medicines is represented by a formula (II), wherein R1 represents one of linear alkyl, terminal hydroxyl or sulfydryl-substituted alkyl, oligomeric polyethylene glycol or 1,4-alkyl piperazine; R2 represents one of hydroxyl, amino and methoxyl; and the characters of the medicines are screened by virtue of a bactericidal experiment. The invention discloses a preparation method and a screening method of synthesized medicines. According to the preparation method and the screening method, the development cost of a new medicine can be lowered, and the detection efficiency of the new medicine can be effectively improved.

Use of cell autophagy (type II cell apoptosis) inhibitors for preventing and/or treating avian influenza, injury of lungs caused by avian influenza virus or nanometer materials. The cell autophagy (type II cell apoptosis) inhibitors are selected from 3-methyladenine, SB203580, LY294002, and or wortmannin. The injury of lungs includes acute respiratory distress syndrome. The avian influenza virus is H5N1, H5N2 or H9N2 avian influenza virus. The nanometer materials include PAMAM G3, G4, G5, G5.5, G6, G7, or G8.