The invention discloses comb shell oligopeptide. The comb shelloligopeptide is composed of an amino acid residue A and an amino acid residue K, and the molecular weight is 217.27 Da. The comb shell oligopeptide and lota-carrageenan are mixed at a certain proportion, and composite gel is prepared through the method of heating, swelling and cooling and gelling. Meanwhile, the invention discloses a virtual screeningmethod of the comb shell oligopeptide. The comb shell oligopeptide is obtained through the steps of raw material pretreatment, SDS-PAGE analysis, protein mass spectrum identification,protein sequence screening, in silico analysis, target peptide screening and synthetic peptide preparation. The method is simple in step, convenient to operate and economical, and saves time and labor, the prepared composite gel has the advantages of being high in elasticity performance and high in strength, has high nutritive valueand can serve as a raw material of the edible colloid industry, the variety of ediblecolloid products is enriched, absorption of the composite gel by the human body is easy, and wide applicationprospects are achieved.