10 results about "Blood compatibility test" patented technology

The invention discloses a risk assessment system for difficulty in cross matching of blood, and relates to the technical field of clinical medical examination and blood transfusion management. The system comprises a data input module, a risk calculation module, a risk layering module and a result output and suggestion module. The data input module obtains key information of a patient, wherein the key information comprises an erythrocyte irregular antibody screening result, multiple myeloma diagnosis, hematology department medical history, age of more than or equal to 60 years, pregnancy-related disease state and blood type identification difficulty; the risk calculation module adopts a preset scoring algorithm to endow each factor with a weight and calculates a total risk score; the risk layering module divides the patients into three levels of low risk, medium risk and high risk; and the result output module provides differentiated clinical management paths corresponding to the risk levels. According to the method, early warning of difficulty in cross matching of blood is achieved through quantitative evaluation, blood transfusion process efficiency can be optimized, clinical risks can be reduced, and the method has good prediction performance (AUC = 0.819) and a high negative prediction value (93.7%).

The application discloses a kind of preparation and application of microbial basic protein and adhesive proteoglycan hydrogel, belong to the field of biomaterials.Basic protein is extracted from microbial cells in the present application, using supramolecular assembly method, basic protein and acidic polysaccharide electrostatic assembly protein glycan gel material with strong tissue adhesion, the method is simple, widely available, and the cost is almost negligible.The tissue adhesive provided by the present application has immediate tissue adhesion performance, excellent biocompatibility and excellent antibacterial ability and hemostatic performance, which is beneficial to cope with different types of bleeding scene and irregular wound healing.Through cell compatibility and blood compatibility test, the results show that the material has excellent biocompatibility, and the basic protein has super strong bacteriostatic ability, avoids the invasion of foreign bacteria in the wound repair process, and has strong healing ability, greatly shortens the healing period of wound.

The utility model discloses a blood transfusion cross-matching inspection test tube rack, which particularly relates to the technical field of medical equipment and comprises a bottom plate, a fixing frame is fixedly arranged at the top of the bottom plate, a limiting groove is formed in the surface of the bottom plate, a limiting block is clamped in the limiting groove, and a movable frame is fixedly arranged at the top of the limiting block. Two shells are arranged between the fixed frame and the movable frame, clamping mechanisms are fixedly arranged in the two shells, each clamping mechanism comprises a sponge layer fixedly arranged in the corresponding shell, a plurality of placement grooves with different hole diameters are formed in the surface of each sponge layer, a plurality of test tube holes with different hole diameters are formed in the surface of each shell, and the test tube holes are communicated with the placement grooves. The test tube holes correspond to the placement grooves in position, and a partition plate is fixedly arranged at the top of the sponge layer. According to the test tube rack, test tubes with different sizes can be conveniently fixed, the test tubes can be conveniently taken and used, meanwhile, the heights and angles of the test tubes can be conveniently adjusted, and the reaction of solvents in the test tubes can be better observed.

1. The name of the design product: full-automatic blood type analyzer. 2. The use of the design product: using column agglutination method, together with the matching detection reagent, for ABO system blood type typing, Rh system blood type typing, irregular antibody screening, cross matching and direct anti-human globulin test on human blood samples in clinical application. 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: perspective view.

The application discloses a risk assessment system for cross matching difficulty, and relates to the technical field of clinical medical examination and blood transfusion management. The system comprises a data input module, a risk calculation module, a risk stratification module and a result output and suggestion module. The data input module obtains key information of a patient, including irregular red blood cell antibody screening results, multiple myeloma diagnosis, hematology department medical history, age of 60 years or older, pregnancy-related disease state and blood type identification difficulty; the risk calculation module adopts a preset scoring algorithm to assign weights to each factor and calculate a total risk score; the risk stratification module divides the patient into three grades of low risk, medium risk and high risk; and the result output module provides a differentiated clinical management path corresponding to the risk grade. The application realizes early warning of cross matching difficulty through quantitative assessment, can optimize the efficiency of the blood transfusion process and reduce clinical risk, has good prediction performance (AUC=0.819) and a high negative predictive value (93.7%).

The invention discloses a blood group reagent quality control kit and application thereof, the blood group reagent quality control kit comprises a plurality of independently subpackaged composite quality control products, and each quality control product simultaneously comprises quality control red blood cells with known antigen spectra and quality control plasma with known antibody spectra; the quality control red blood cells are human red blood cells with known ABO blood type, RhD blood type and Rh haplotype; the quality control plasma contains blood group antibodies with known specificity and immune globulin types, and the blood group antibodies comprise IgM antibodies and / or IgG antibodies. The invention also discloses application of the blood group reagent quality control kit in indoor quality control of blood group serology detection and an indoor quality control method of blood group serology detection. The kit provided by the invention can realize integrated and efficient detection, and synchronously complete indoor quality control of a plurality of core items such as blood type identification, antibody screening, cross matching of blood and the like.

The invention discloses a pulsating flow blood injury assessment system and method for a double-loop nested low-pre-charge medical instrument, and belongs to the technical field of medical instruments. The system comprises a physiological pulsating pressure simulation loop and an instrument test blood carrying loop. The physiological pulsating pressure simulation loop is composed of a mechanical human body circulation simulation system and comprises a left ventricle, an aorta compliance cavity, a pipeline, a sensor and a power system. The instrument test blood carrying loop comprises a flexible blood bag, a blood carrying pipeline and a to-be-tested medical instrument. The two loops are nested and coupled through the flexible blood bag, and the flexible blood bag is immersed in water-glycerol liquid of the physiological pulsating pressure simulation loop to realize non-contact pressure transmission. The total blood pre-filling amount of the system is smaller than 500 mL, an SEBS blood bag and a heparinization coating are adopted, a non-contact sensor and an actuator are combined, and extra blood damage is remarkably reduced. According to the invention, low-pre-charge and high-biocompatibility pulsating flow blood injury accurate evaluation is realized, and the method is suitable for blood compatibility test of medical instruments such as a ventricular assist device and the like.

The invention belongs to the technical field of red blood cell washing, and particularly relates to full-automatic constant-temperature red blood cell washing equipment for cross blood matching and red blood cell inspection, which comprises a washing equipment body with a constant-temperature function and a partition plate arranged in the washing equipment body, after the washing container is clamped and fixed through the linkage turnover mechanism, the linkage turnover mechanism can drive the clamped and fixed washing container to rotate by a certain angle under the action of a linkage toothed plate in the process of driving the linkage turnover mechanism to stretch out and draw back left and right through the stretching mechanism; the inclination angle of the washing container can be adjusted to meet different centrifugal requirements, in the process that the stretching mechanism and the washing container are driven by the rotary driving mechanism to rotate for centrifugation, the stretching mechanism is controlled to do reciprocating telescopic motion to control the washing container to swing back and forth, and the washing effect is improved through composite motion of rotary centrifugation and reciprocating swing. And the centrifugal efficiency and the washing effect can be greatly improved.

The utility model discloses a reagent classification storage frame special for blood transfusion laboratory, reagent classification storage frame special for blood transfusion laboratory includes setting on the first storage area of base, second storage area, third storage area and fourth storage area, set at least one first installation groove for the installation irregular antibody screening cell reagent on the first storage area, set at least one second installation groove for the installation blood type reverse type reagent on the second storage area, set at least one third installation groove for the installation blood type positive type and Rh (D) blood type type reagent on the third storage area, and the fourth storage area is provided with the fourth installation groove for the installation agglutination amine cross matching blood reagent, the utility model discloses four storage areas and sets up the installation groove of corresponding specification reasonably, realizes the orderly classification and fixed placement of reagent, effectively avoids the risk of reagent bottle falling and taking confusion, simultaneously, through the corresponding design of name mark and installation groove, further improves the accuracy and efficiency of reagent taking.

The invention discloses an adjustable sampling device for cross blood matching examination, and relates to the technical field of medical instruments, the adjustable sampling device comprises a device main body, the top of the interior of the device main body is rotatably provided with a bidirectional screw rod, and one side of the top of the device main body is fixedly provided with a first servo motor; a transmission gear is fixedly installed at the output end of the first servo motor, a driven gear is fixedly installed on the outer side of the bidirectional lead screw and meshed with the transmission gear, a limiting rod is fixedly installed in the device body and located above the bidirectional lead screw, and two first sliding blocks are installed on the outer side of the bidirectional lead screw in a threaded mode. The device has the beneficial effects that the position of the dropper can be automatically adjusted according to the positions of the placed test tubes filled with serum of a blood supplier and a blood receiver and unused test tubes in the blood cross matching process, then the serum of the blood supplier and the blood receiver is sampled and then dropped into the test tube to be dropped, and the serum of the blood supplier and the blood receiver can be sampled and inspected at the same time; the working efficiency is high.