41 results about "Coriolus versicolor extract" patented technology

The invention discloses a health-care food for liver-protection and a preparation method thereof. The health-care food for liver-protection comprises the components (part by weight) that: 20 to 40 portions of Cordyceps militaris, 30 to 50 portions of reishi shell-broken spore powder, 5 to 15 portions of Lucid Ganoderma spore polysaccharose, 5 to 15 portions of Coriolus Versicolor extract, 0.8 to 1.2 portions of glidant and 0.8 to 1.2 portions of lubricant. After a series of technologies such as mixing and granulating, and drying etc., by combining physicochemical property and considering from multiple aspects such as function, absorption and stability, etc., the raw materials are made into product dosage forms such as capsules, troches and granular formulation, etc. The invention puts emphasis on the crowd as a research object, and the product dosage forms are manufactured by reasonable technology, thus having the characteristics of high bioavailability and convenient use, etc.

The invention relates to a traditional Chinese medicine composition for treating tumors, the traditional Chinese medicine composition comprises ganoderma lucidum, ganoderma sinensis, coriolus versicolor, antrodia camphorate, agaricus blazei, grifola frondosa, ginseng and ganoderma lucidum spore oil; or the traditional Chinese medicine composition is prepared by taking ganoderma lucidum, ganoderma sinensis, coriolus versicolor, antrodia camphorate, agaricus blazei, grifola frondosa, ginseng and ganoderma lucidum as raw materials and further comprises ganoderma lucidum extract, ganoderma sinensis extract, coriolus versicolor extract, antrodia camphorate extract, agaricus blazei extract, grifola frondosa extract, ginseng extract and the ganoderma lucidum spore oil. The traditional Chinese medicine composition for treating the tumors can assist to suppress the growth of the tumors, resist the injuries of chemo-radiation therapy, promote the bone marrow hematopoiesis and improve the immunity. The invention further relates to a production method of the traditional Chinese medicine composition for treating the tumors.

The invention discloses skin rejuvenating and regeneration essence. The skin rejuvenating and regeneration essence comprises collagen, fibroin, coriolus versicolor extract, ceramide, hyaluronic acid, vitamin E acetate and water. The skin rejuvenating and regeneration essence has the advantages of small molecules, natural and mild properties and no irritation, can be used for moisturizing skin for a long time, has good water replenishment effects on dry skin and sensitive skin, can improve skin elasticity, realizes combination of regeneration, water replenishment, spot fading and regeneration, improves skin moisturizing and regeneration effects, and soothes the traces of the years. The powerful essence can be fast absorbed by skin, make skin elastic and compact and provide silk-like gloss for the skin.

The invention relates to an extraction process of coriolus versicolor polysaccharide. The method comprises the following steps: extracting water-soluble polysaccharide from coriolus versicolor; after decolorization, adding cellulase and neutral protease, wherein the addition amount of the cellulase of which the enzyme concentration is 1.5 percent is 4-6 percent of that of a supernatant, the addition amount of the protease of which the enzyme concentration is 1.5 percent is 2-4 percent of that of the supernatant, the pH is adjusted as 6.5, the temperature is 45-55 DEG C, and the time is 60-90min; concentrating under reduced pressure until the volume is 70 percent of the original volume, and performing suction filtration to obtain clear liquid; washing the clear liquid by using absolute ethyl alcohol, and precipitating and drying the clear liquid to obtain a coriolus versicolor extract, wherein the content of the coriolus versicolor polysaccharide is 32-45 percent. The coriolus versicolor extract is obtained by double-enzyme enzymolysis fermentation, the process is simple, the cost is lower, and the extraction rate is high. Particularly, the cellulase is used for wall breaking treatment, and the protease is used for protein removal treatment, so that the defects of low solubility and the like caused by macromolecule protein are avoided, the biological activity of the coriolus versicolor polysaccharide is improved, and the coriolus versicolor polysaccharide can be better absorbed and utilized by a human body.

The invention discloses anti-wrinkle moisturizing moisture retention essence. The anti-wrinkle moisturizing moisture retention essence disclosed by the invention is prepared from the following raw materials of tremella extract, fibroin polypeptide, sea algae extract, sodium hyaluronate, coriolus versicolor extract, natto extract, lavender extract, thyme herb extract, immortelle flower extract, chitosan-nanosilver colloid solution, a stabilizer and water. The invention further discloses a preparation method of the anti-wrinkle moisturizing water locking essence. Compared with the prior art, theanti-wrinkle moisturizing water locking essence is prepared from micromolecular matter, is like silky essence, can penetrate through skin cuticula within ten seconds, can be quickly absorbed and utilized by the skin, can form thin and overlapped layers on the face, presents silky color, can make the skin be elastic and compact, can flatten fine wrinkles, can delay skin ageing, can promote young cell regeneration and makes the skin show brightness and glossiness.

The subject invention provides Coriolus versicolor extracts, pharmaceutical compositions comprising the Coriolus versicolor extracts, methods of preparation, and therapeutic uses thereof. Advantageously, the subject Coriolus versicolor extract has immunomodulatory, anti-tumor, anti-microbial, and antiviral effects. In a preferred embodiment, the subject invention can be used to inhibit the metastatic spread of cancer cells. In certain preferred embodiments, the subject invention can be used to treat glioblastoma multiforme, nasopharyngeal carcinoma, breast carcinoma, lung carcinoma, prostate cancer, and colon carcinoma, as well as bacterial, viral, fungal, protozoan, and/or other microbial infection.

The invention discloses yam and jujube dispersible tablets comprising the following components in parts by weight: 80-120 parts of yam, 10-30 parts of jujube, 40-60 parts of microcrystalline cellulose, 0.12-0.32 part of hawthorn extract, 0.12-0.32 part of coriolus versicolor extract, 0.12-0.32 part of isolated soy protein, 1-2 parts of vitamin C, 0.01-0.02 part of vitamin E, 100-170 parts of mannitol, 10-15 parts of sucralose, 10-50 parts of aerosol, 3-5 parts of carboxymethylcellulose, 55-80 parts of sodium carboxymethyl starch, 4-6 parts of magnesium stearate and an appropriate amount of 75% ethanol. The yam and jujube dispersible tablets disclosed by the invention have an effect of invigorating spleen and tonifying kidney and are suitable for long treatment of thin paste-shaped children excrements.

The invention belongs to the technical field of foods and discloses a health food for relieving a chemical liver injury and a preparation method of the health food. The health food comprises the following components by mass percent: 40% to 60% of coriolus versicolor extract, 20% to 30% of grape seed extract and 10% to 40% of wolfberry extract. The preparation method comprises the following steps: respectively extracting active ingredients from coriolus versicolor, grape seeds and wolfberries to obtain a coriolus versicolor extract, a grape seed extract and a wolfberry extract; and evenly mixing the three extracts so as to obtain the health food for relieving the chemical liver injury. The obtained health food has the advantages of high active ingredients and good chemical liver injury relieving effect, and is convenient to use. Thus, the obtained health food has a wide market prospect.

The invention relates to eye drops containing active ions. The eye drops are prepared from the following components: 4-6 parts of active calcium ion powder, 3-5 parts of momordica charantia extract, 3-5 parts of gynostemma pentaphylla extract, 3-5 parts of gingko leaf extract, 3-5 parts of coriolus versicolor extract, 30-50 parts of lemon hydrolat, 40-60 parts of rosemary hydrolat, 30-50 parts of tea tree hydrolat and 1-3 parts of citric acid. The invention provides pure natural organic extract eye drops and a preparation method thereof. The eye drops are prepared from pure natural components, have the effects of diminishing inflammation, moistening and improving eyesight, is healthy and maintaining, does not have side effect, can be used for protecting optic nerves and nourishing modern TV watchers, computer users and other people with eye fatigue, is capable of durably moistening, keeping high water content and moistening eyes, and has a good relieving effect on dry or uncomfortable eyes caused by contact lenses.

The invention discloses black bean and plantain seed dispersible tablets comprising the following components in parts by weight: 300-400 parts of yam, 300-400 parts of black beans, 80-120 parts of semen coicis, 80-120 parts of cuttle-bone, 80-120 parts of cockscomb, 60-80 parts of semen euryales, 40-60 parts of plantain seeds, 20-40 parts of ginger, 120-160 parts of jujube, 40-60 parts of microcrystalline cellulose, 0.12-0.32 part of coriolus versicolor extract, 0.12-0.32 part of hawthorn extract, 0.35-0.75 part of pearl powder, 0.003-0.007 part of ferrous lactate, 1-2 parts of vitamin C, 0.003-0.007 part of vitamin E, 100-170 parts of mannitol, 10-15 parts of sucralose, 10-50 parts of aerosol, 3-5 parts of carboxymethylcellulose, 55-80 parts of sodium carboxymethyl starch and 4-6 parts of magnesium stearate. The black bean and plantain seed dispersible tablets have effects of tonifying kidney, invigorating spleen, removing dampness through diuresis, increasing immunity, increasing bone density, improving alimentary anemia and the like, and are suitable for black leucorrhea mingled with white and yellow leucorrhea and the like caused by kidney deficiency and spleen deficiency with wetness, and are used for assisted rehabilitation.

The invention discloses a ramie root and teasel root dispersible tablet. The ramie root and teasel root dispersible tablet comprises following components in parts by weight: 400-600 parts of Chinese yams, 100-300 parts of ramie roots, 100-300 parts of teasel roots, 100-300 parts of eucommia ulmoides, 40-60 parts of microcrystalline cellulose, 0.12-0.32 part of coriolus versicolor extract, 0.35-0.75 part of pearl powder, 0.12-0.32 part of ferrous lactate, 1-2 parts of vitamin C, 0.003-0.007 part of vitamin E, 120-150 parts of mannitol, 10-15 parts of trichlorosucrose, 20-40 parts of superfine silica powder, 3-5 parts of carboxymethylcellulose, 55-80 parts of sodium carboxymethyl starch, 4-6 parts of magnesium stearate and a proper amount of purified water. The ramie root and teasel root dispersible tablet has the effects of reinforcing the kidney, tonifying qi and preventing miscarriage, enhancing the immunity, increasing the bone density, improving the alimentary anemia and the like, is suitable for habitual abortion and is used for assisting the recovery.

The invention discloses a Chinese yam and pericarpium citri reticulatae viride dispersible tablet. The Chinese yam and pericarpium citri reticulatae viride dispersible tablet comprises following components in parts by weight: 100-300 parts of Chinese yams, 100-300 parts of pericarpium citri reticulatae viride, 40-60 parts of microcrystalline celluloses, 0.12-0.32 part of astragalus extract, 0.12-0.32 part of coriolus versicolor extract, 4-6 parts of soy isolate protein, 1-2 parts of vitamin C, 0.01-0.02 part of vitamin E, 100-170 parts of mannitol, 10-15 parts of trichlorosucrose, 10-50 parts of superfine silica powder, 3-5 parts of carboxymethylcellulose, 55-80 parts of sodium carboxymethyl starch, 4-6 parts of magnesium stearate and a proper amount of 75% ethanol. The Chinese yam and pericarpium citri reticulatae viride dispersible tablet has the effects of soothing liver-qi stagnation, enhancing the immunity and the like. The Chinese yam and pericarpium citri reticulatae viride dispersible tablet is applicable to postpartum galactorrhea, such as more and sticky breast milk, breast distending pains, uncomfortable emotions, irritation, cardiopalmus, dry excrement and the like, and is used for assisting the recovery.

The invention discloses a preparation method of a coriolus versicolor extract, which comprises the following steps: S1, freezing and embrittling coriolus versicolor sporocarp at -15 to 5 DEG C for 30min, pulverizing and drying the coriolus versicolor sporocarp, carrying out screening with a 60-mesh sieve, and carrying out degreasing with 95% ethanol to obtain coriolus versicolor sporocarp powder;S2, adding water which is 8-15 times of the coriolus versicolor sporocarp powder into the coriolus versicolor sporocarp powder, adding cellulase according to a mass percentage of 1-2%, adjusting the pH value to 6.0, and carrying out enzymolysis at 45-55 DEG C for 20-30min to obtain an enzymatic hydrolysate; and S3, repeatedly freezing and thawing the enzymatic hydrolysate for three times, carryingout spray drying, carrying out soaking in a proper amount of 2% Na2CO3 solution under a negative pressure condition for 10min, instantaneously recovering to normal pressure, carrying out ultrasonic extraction at 35-50 DEG C for 30-50min, carrying out suction filtration, repeating ultrasonic extraction once, and carrying out drying to obtain the extract. The method is high in extraction rate, andthe obtained extract contains few impurities.

The subject invention provides efficient and convenient methods of isolating 9-oxo-10E, 12E-octadecadienoic acid methyl ester (9-KODE methyl ester) from C. versicolor. In addition, the subject invention provides therapeutic uses of Coriolus versicolor extracts, biologically-active chemical substituents isolated from C. versicolor, as well as 9-KODE methyl ester and related compounds. In a preferred embodiment, the subject invention can be used to inhibit the metastatic spread of cancer cells.

The invention discloses cuttlefish bone-ginkgo dispersible tablets. The cuttlefish bone-ginkgo dispersible tablets contain the following ingredients in weight: 400g-600g of yam, 100g-140g of cuttlefish bones, 100g-140g of cedrela sinensis bark, 50g-70g of ginkgo, 40g-60g of microcrystalline cellulose, 0.12g-0.32g of coriolus versicolor extract, 0.38g-0.78g of calcium carbonate, 0.011g-0.022g of ferrous fumarate, 1g-2g of vitamin C, 1-2 micrograms of vitamin D, 100g-170g of mannitol, 10g-15g of sucralose, 10g-50g of micro-powdered silica gel, 3g-5g of carboxymethyl cellulose, 55g-80g of sodium carboxymethyl starch, 4g-6g of magnesium stearate and 1mg of alpha-amylase. The cuttlefish bone-ginkgo dispersible tablets have the effects of invigorating spleen and kidney, drying dampness to stop leukorrhagia, strengthening immunity, increasing bone mineral density, improving nutritional anemia, and the like, are applicable to clear and thin leukorrhea, the soreness of waist and legs and the like and are used for assisting rehabilitation.

The invention discloses a liver-protecting preparation containing traditional Chinese medicine fructus broussonetiae, and particularly relates to the technical field of liver-protecting preparations. The liver-protecting preparation is prepared from the following raw materials in parts by weight: 1.2-2.2 parts of fructus lycii, 1.5-2.3 parts of radix angelicae sinensis, 1.5-2.3 parts of fructus forsythiae, 1.2-2.2 parts of fructus forsythiae, 1.5-2.3 parts of fructus The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 2.5 to 2.8 parts of red dates, 2.6 to 3.5 parts of pulvis fellis suis, 1.5 to 2.6 parts of fructus schisandrae chinensis, 2.3 to 2.9 parts of radix isatidis, 1.8 to 2.2 parts of herba artemisiae scopariae, 1.2 to 2.4 parts of radix bupleuri, 2.5 to 3.2 parts of silibinin, 1.2 to 2.2 parts of coriolus versicolor extract, 2.5 to 2.9 parts of rhizoma cyperi, 2.4 to 2.8 parts of radix paeoniae rubra, 1.2 to 1.6 parts of radix rehmanniae, 1.6 to 1.9 parts of rhizoma polygoni cuspidati, 0.5 to 1.3 parts of fructus broussonetiae, 2.5 to 2.8 parts of glucurolactone, 2.4 to 2.8 parts of anethol trithione and 1.4 to 1.6 parts of immunomodulator. The liver protection preparation containing the traditional Chinese medicine fructus broussonetiae prepared by the invention not only is effective for patients with acute and chronic hepatitis, but also can be used for treating patients with cholecystitis.