The invention discloses a quasi real-time space time mixed modulation infrared interference spectrum imaging system, method and application. According to the system, an infrared thermal radiation signal reaches a scanning mirror 3 through an infrared optical window 1, a time modulation signal is generated, the time modulation signal goes through a space modulation interference tool 4, time and space mixed modulation imaging interferometry are generated at the same time, optical lights are gathered and collected through a Fourier lens 15, the optical signals enter into a detector assembly 6 and then an electrical signal is outputted, the electrical signal goes through a high-speed image processing circuit 7 and an infrared image sequence is imaged, the sequence is inputted to a CUDA architecture parallel computer 9 through a digital image data interface 8, an interference data cube is formed, the interference data cube goes through a data cube and is converted through a parallel fast Fourier transform algorithm 10, and information is displayed on an image display 14 after processing. The imaging system has no slit, the luminous flux is large, and the automatic interference signal acquisition and quasi real-time imaging spectroscopy gas detection can be realized.