72 results about "Intracranial Cavity" patented technology

An endoscopic system and method that is adaptable for therapeutic applications as well as sensor operation and is capable of producing 3-dimensional human vision simulated imaging with real dynamic convergence, not virtual convergence. Applications may include use in any space, including but not limited to, intra-abdominal cavities, intra-thoracic cavities, and intra-cranial cavities. Further, two or more diagnostic / sensor probes may be used, with at least two being the same kind to create the 3-dimensional effect, such as but not limited to, camera, ultrasound, and magnetic-resonance imaging. Diagnostic / sensor probes are each mounted to the end of a different arm, with the other ends of the two arms both being attached to the same hinge that allows them to turn freely on the same axis from side-to-side within a 180 degree angle range of movement on the distal end of a main tubular shaft system. Medical, as well as other applications, are contemplated.

The object of providing a cerebrospinal fluid drainage system 1 which reacts precisely to changes in pressure in the cerebrospinal fluid, with ease of operation, is achieved by the present invention in that a pump 5 is used for draining the cerebrospinal fluid (liquor), wherein operating measured values supplied by sensors act as controlled variable for the operation of the pump. The pressure in the liquor line currently measured by a pressure sensor 10, the liquor pressure in the intracranial cavity being treated, measured intracorporeally by a pressure sensor, and / or the volume of liquor already pumped out, as operating measured value, can, for example, serve as the basis for operational control of the pump of the liquor drainage system. The liquor drainage system according to the invention has the advantage that the liquor is drained not only simply on the basis of the excess pressure in the intracranial cavity being treated, but is actively pumped out of the intracranial cavity in a controlled manner, in particular with constant measurement of the liquor pressure. In this way the pumping capacity can be regulated depending on requirement and the drainage pressure or the liquor pressure kept reliably within a specific pressure range.

A system for reducing the damaging effects of radiant energy, blast, or concussive events includes applying pressure to at least one jugular vein to reduce the egress of blood from the cranial cavity during or before the incidence of the imparting event. Reducing blood outflow from the cranial cavity increases intracranial volume and / or pressure of the cerebrospinal fluid to reduce the risk of traumatic brain injury and injuries to the spinal column. Reducing blood outflow further increases the intracranial pressure and volume, and thereby increases the pressure and volume of the cochlear fluid, the vitreous humor and the cerebrospinal fluid to thereby reduce the risk of injury to the inner ear, internal structure of the eye and of the spinal column. In addition, increasing intracranial pressure and volume reduces the likelihood of brain injury and any associated loss of olfactory function

An adjustable drainage system for regulating cerebrospinal fluid flow in a hydrocephalus patient where the drainage rate is adjusted in response to ventricular volume variations in the patient. The system includes an adjustable valve and a volume sensor that can be periodically energized with an external system controller device by the patient or attending physician to determine when, or if, a change in the ventricular volume has occurred. The system enables the user to adjust the valve's resistance in response to changes in the ventricular volume using the controller device so that a target ventricular volume can be achieved. Also provided is a method of continuously draining cerebrospinal fluid from the cranial cavity of the patient using the system of the present invention.

The invention provides a nano artificial dura mater capable of being used as a medicine sustained-release system, having the structure which comprises at least two layers, i.e. a hydrophobic anti-blocking electro-spun layer which faces the cerebrum, and a hydrophilic nano cytoskeleton layer which backs on to the cerebrum; and cell factors and / or medicines are arranged in any layer of the artificial dura mater by way of blended spinning. The invention also provides a method for preparing the nano biomimic artificial dura mater. Compared with an artificial mater prepared by the single utilization of the electro-spinning technology, the artificial mater to which the medicines and the cell factors are added by blending technology can effectively prevent infection and faster promote the regeneration process of the artificial mater. The invention also provides a novel medicine loading and releasing mode for treating cerebral diseases, the loaded medicines can be directly and efficiently transferred into the cranial cavity along with the implantation of the dura mate and can be released according to requirements, and therefore the invention realizes favorable treatment effect and has broad application prospect.

A method and device for reducing the damaging effects of radiant energy, blast, or concussive events includes applying pressure to at least one jugular vein to reduce the egress of blood from the cranial cavity during or before the incidence of the imparting event. Reducing blood outflow from the cranial cavity increases intracranial volume and / or pressure of the cerebrospinal fluid to reduce the risk of traumatic brain injury and injuries to the spinal column. Reducing blood outflow further increases the intracranial pressure and volume, and thereby increases the pressure and volume of the cochlear fluid, the vitreous humor and the cerebrospinal fluid to thereby reduce the risk of injury to the inner ear, internal structure of the eye and of the spinal column. In addition, increasing intracranial pressure and volume reduces the likelihood of brain injury and any associated loss of olfactory function

A method and device for reducing the damaging effects of radiant energy, blast, or concussive events includes applying pressure to at least one jugular vein to reduce the egress of blood from the cranial cavity during or before the incidence of the imparting event. Reducing blood outflow from the cranial cavity increases intracranial volume and / or pressure of the cerebrospinal fluid to reduce the risk of traumatic brain injury and injuries to the spinal column. Reducing blood outflow further increases the intracranial pressure and volume, and thereby increases the pressure and volume of the cochlear fluid, the vitreous humor and the cerebrospinal fluid to thereby reduce the risk of injury to the inner ear, internal structure of the eye and of the spinal column. In addition, increasing intracranial pressure and volume reduces the likelihood of brain injury and any associated loss of olfactory function

A burr hole sealing device for preventing brain shift during a stimulation lead implantation procedure is provided. The device includes a suction cup ring and a self-sealing membrane positioned within the aperture of the ring. The sealing device is attached adjacent to a burr hole and over a dura layer that is exposed in the bottom of the burr hole. The stimulation lead is disposed through the burr hole, through the membrane, through the dura layer and into brain tissue. The membrane is configured to allow the lead to pass therethrough while maintaining a tight seal around the diameter of the lead, thereby hindering leakage of cerebrospinal fluid out of the cranial cavity and maintaining a substantially fixed intracranial pressure. In one embodiment, the sealing device includes a syringe for adding fluid to, or removing fluid from, the cranial cavity in response to a detected change in intracranial pressure.

The invention discloses a treatment instrument for intracranial pressure monitoring and drainage and replacement of cerebrospinal fluid. The treatment instrument combines the drainage treatment technology of a cerebrospinal fluid waist penetrating pipe with the computer virtual instrument technology. The treatment instrument comprises an outer connecting pipe, a pressure monitoring branch, a drainage loop and a replacement loop, wherein the pressure sensor transfers real-time pressure of the cranial cavity to a control system; and the drainage loop and the replacement loop feed back drainage amount and replacement amount to the control system which controls a drainage device / replacement device to work or stop so as to drain / replace the cerebrospinal fluid. The instrument can be widely applicable to places where the intracranial pressure of a patient needs to be continuously monitored and drainage and replacement needs to be carried out on the cerebrospinal fluid in the neurology department and the neurosurgery department, replaces the current manual drainage and replacement operations carried out according to experience, realizes automation of the sections such as pressure monitoring, drainage and replacement in treatment and can continuously acquire and store real-time data in treatment.

The present invention relates to devices and systems that alter intracranial compliance, cerebral blood flow and / or intracranial pressure pulsatility / waveform by oscillating the contraction and expansion of a compressible composition within the cranial or spinal cavities such that they increase intracranial capacity. The contraction and expansion of the compressible composition in the oscillating compliance devices can be due to an individual's intracranial pressure, the result of the expansion and compression of a reservoir which is mediated by the contractility of the heart or driven by a pump gaited to a biorhythm. The invention also relates to methods for protecting an individual's brain from abnormal arterial pulsations and for altering an individual's cerebral blood flow using the devices and systems of the invention. The oscillating compliance devices can be used to treat several diseases and / or conditions characterized by altered / abnormal intracranial compliance, cerebral blood flow and / or intracranial pressure pulsatility / waveform, including hydrocephalus, stroke, dementia and migraine headaches, vasospasms, congestive heart failure, cardiopulmonary bypass or carotid endarterectomy.

A method and device for reducing the damaging effects of radiant energy, blast, or concussive events includes applying pressure to at least one jugular vein to reduce the egress of blood from the cranial cavity during or before the incidence of the imparting event. Reducing blood outflow from the cranial cavity increases intracranial volume and / or pressure of the cerebrospinal fluid to reduce the risk of traumatic brain injury and injuries to the spinal column. Reducing blood outflow further increases the intracranial pressure and volume, and thereby increases the pressure and volume of the cochlear fluid, the vitreous humor and the cerebrospinal fluid to thereby reduce the risk of injury to the inner ear, internal structure of the eye and of the spinal column. In addition, increasing intracranial pressure and volume reduces the likelihood of brain injury and any associated loss of olfactory function.

The invention relates to an efficient and environment-friendly remains preservative free of formaldehyde and application thereof. The remains preservative mainly comprises, by volume, 0.5-10% of phenoxyethanol, 0.2-1.5% of isothiazolinone, 3-15% of organic acid, 5-20% of propylene glycol, 5-30% of glycerol, 20-75% of ethanol and 5-35% of distilled water, and, by weight, 1-10% of hexamethylenetetramine and 0-2% of ethylenediamine tetraacetic acid disodium salt. The preservative can be poured through an aorta and an aortic arch and injected through the abdominal cavity, the thoracic cavity, the pharyngeal cavity and the cranial cavity so as to carry out antiseptic preservation, disinfection and smell removal to remains. Quantification sterilization experiments, animal experiments and funeral home field experiments prove that the remains preservative is efficient in antibacterial property, quick in action speed, low in toxicity and suitable for short-term or long-term remains antisepsis or specimen preservation of funeral homes and medical colleges at home and abroad.

The invention discloses a nano probe material for imaging, which is capable of efficiently breaching blood-brain barriers. Firstly, a high temperature pyrolysis method is adopted for preparing inner core NaYF4:Yb / TM / Gd hydrophobic nano-particles, then an NaGdF4 shell is formed through epitaxial growth so as to form core / casing structured NaYF4: Yb / Tm / Gd and NaGdF4 nano-particles, then hydrochloric acid hydrophilic modification and sulfhydryl PEG modification are performed, and finally, the nano probe material is prepared through Angiopep-2 grafting, and is marked as ANG / PEG-UCNPs. The material can be used for efficient blood-brain barrier breaching, magnetic resonance imaging diagnosis and positioning before an cranial cavity glioma operation, near infrared fluorescence imaging in the operation and image mediating, the imaging effect is good, the sensitivity is high, the physiological system toxicity is low, and the material plays an important significance in successful clinic glioma removing operations and the development and the application of medical image diagnostic techniques.

The invention relates to a noncontact magnetic sensing-type intracranial pressure monitoring device, which comprises an excitation source for generating an excitation signal and a reference signal, a magnetic sensing detection device surrounding a tested head and a phase discriminator, wherein the magnetic sensing detection device is connected to the output end of the excitation source, an alternating excitation magnetic field signal is generated according to an excitation signal provided by the excitation source, the excitation magnetic field signal runs through the entire tested head, the excitation magnetic field signal and a secondary magnetic field signal are superimposed together to form a superimposed magnetic field signal having phase change relative to the reference signal; the phase discriminator is used for detecting phase difference between the reference signal and the superimposed magnetic field signal, and the phase difference is used for reflecting the pressure variation of the wall of a cranial cavity caused by intracranial contents. Due to the adoption of the noncontact magnetic sensing-type intracranial pressure monitoring device, the defect that inductively coupled plasma (ICP) monitoring cannot sensitively reflect the variation of early lesion because the ICP is not increased greatly under the adjustment effect of cerebrospinal fluid and cerebral blood flow dynamics when the early lesion of the brain causes the increase of ICP can be overcome.

The invention discloses an implantable intracranial pressure monitoring probe and belongs to human cranial cavity monitoring devices. The implantable intracranial pressure monitoring probe comprises a probe body, wherein a groove is formed nearby the middle of the probe body; a pressure sensor is mounted in the groove; a thermistor is further mounted in the front end of the probe body and placed at the front end of the pressure sensor; wires of both the thermistor and the pressure sensor extend to the tail end of the probe body and are wrapped by wire protecting sleeves; one end of each wire protecting sleeve extends into a butting opening in the tail end of the prove body and is fixedly connected with the inner wall of the butting opening, and the other end of each wire protecting sleeve extends out of the probe body. As the pressure sensor and the thermistor are both mounted on the probe, the probe can simultaneously measure the intracranial pressure and temperature to further eliminate interference on monitoring of intracranial pressure from the temperature; as the pressure sensor is mounted in the groove, after the groove is sealed, the pressure sensor cannot be in contact with external liquid, and accordingly, the pressure measurement accuracy is effectively improved.

A method and device for reducing the damaging effects of radiant energy, blast, or concussive events includes applying pressure to at least one jugular vein to reduce the egress of blood from the cranial cavity during or before the incidence of the imparting event. Reducing blood outflow from the cranial cavity increases intracranial volume and / or pressure of the cerebrospinal fluid to reduce the risk of traumatic brain injury and injuries to the spinal column. Reducing blood outflow further increases the intracranial pressure and volume, and thereby increases the pressure and volume of the cochlear fluid, the vitreous humor and the cerebrospinal fluid to thereby reduce the risk of injury to the inner ear, internal structure of the eye and of the spinal column. In addition, increasing intracranial pressure and volume reduces the likelihood of brain injury and any associated loss of olfactory function.

An active skull replacement system including an implant having an area A, an upper surface, and a bottom surface, adapted to be implanted at least in part into a skull of a subject so to substitute a portion of the skull, the bottom surface arranged to face at least in part a cranial cavity, and having a first wireless bidirectional data communication device, a device operably connected to the bottom surface of the implant, the device adapted to at least one of stimulate a physiological response and record a physiological parameter of the subject, and an external reader adapted to be placed on the scalp of the subject and including a second wireless bidirectional data communication device configured to communicate with the first wireless bidirectional data communication device of the implant to operate the device, wherein the external reader and the implant are fixed and aligned among each other through a magnetic device.

The invention provides an optical fiber craniocerebral pressure monitor. An optical fiber pressure sensor in the monitor is placed in a cranial cavity, under the effect of intracranial pressure, a sensitive membrane of the optical fiber pressure sensor deforms, the reflectivity of incident lasers is changed, reflected light is transmitted to an interference filter through a multimode fiber, only the 1, 310 nm lasers enter a photoelectric detector, the photoelectric detector converts the reflected light with pressure information into electric signals, the electric signals are amplified, analyzed and processed and then displayed on a digital instrument, a recorder is used for continuously tracing a craniocerebral pressure curve, and therefore the changes of the intracranial pressure can be known at any time. The optical fiber craniocerebral pressure monitor can monitor the intracranial pressure of a patient most rapidly, visually and accurately, displays all information of changes of the craniocerebral pressure, and is widely applied to professions such as the neurosurgery, the internal medicine and the department of pediatrics.

An intracranial pressure monitoring instrument based on ultrasonic wave acoustoelastic effect comprises a computer, an ultrasonic wave transmitting drive module, an ultrasonic wave transmitter, an ultrasonic wave receiver and a receiving signal circuit module, wherein the ultrasonic wave transmitting drive module is used for generating initial high-frequency signals, the ultrasonic wave transmitter is connected with the ultrasonic wave transmitting drive module and converts the initial high-frequency signals output by the ultrasonic wave transmitting drive module into elastic mechanical waves transmitting to a cranial cavity, the ultrasonic wave receiver is used for receiving the elastic mechanical waves penetrating the cranial cavity and converting the received elastic mechanical waves into tail-end high-frequency signals, the receiving signal circuit module is connected with the ultrasonic wave receiver and used for performing frequency discrimination and phase locking to the tail-end high-frequency signals and outputting the phase, with the same frequency as the initial high-frequency signals, of the tail-end high-frequency signals to the computer, and the computer is connected with the ultrasonic wave transmitting drive module and the receiving signal circuit module and used for demodulating the tail-end high-frequency signals and calculating intracranial pressure. By the intracranial pressure monitoring instrument, noninvasive monitoring of intracranial pressure of patients is achieved, measuring data is accurate, the clinical application requirements can be satisfied, and long-term online monitoring is achieved.

The object of providing a cerebrospinal fluid drainage system 1 which reacts precisely to changes in pressure in the cerebrospinal fluid, with ease of operation, is achieved by the present invention in that a pump 5 is used for draining the cerebrospinal fluid (liquor), wherein operating measured values supplied by sensors act as controlled variable for the operation of the pump. The pressure in the liquor line currently measured by a pressure sensor 10, the liquor pressure in the intracranial cavity being treated, measured intracorporeally by a pressure sensor, and / or the volume of liquor already pumped out, as operating measured value, can, for example, serve as the basis for operational control of the pump of the liquor drainage system. The liquor drainage system according to the invention has the advantage that the liquor is drained not only simply on the basis of the excess pressure in the intracranial cavity being treated, but is actively pumped out of the intracranial cavity in a controlled manner, in particular with constant measurement of the liquor pressure. In this way the pumping capacity can be regulated depending on requirement and the drainage pressure or the liquor pressure kept reliably within a specific pressure range.

The invention relates to a remains decay-preventing composition, a preparation method and application thereof. The remains decay-preventing composition comprises the following components in proportion: 0.1 to 5 volume portions of isothiazolinone compounds, 5 to 30 volume portions of dibastic alcohol, 3 to 30 volume portions of glycerol, 5 to 30 volume portions of alcohol, 5 to 50 volume portions of hexanol, 0 to 15 weight portions of nipagin esters, 1 to 15 volume portions of dimethyl sulfoxide, 0 to 2 weight portions of ethylenediamine tetraacetic acid disodium salt, 0 to 10 volume portions of acetic acid, 0 to 15 weight portions of urotropine, 1 to 10 volume portions of plant extract and 0 to 15 volume portions of purified water. By pouring preservative into aortas and injecting the preservative into abdominal cavities, thoracic cavities, pharyngeal cavities and cranial cavities, the composition plays a rapid effective role in preventing remains decay. The decay-preventing composition has the advantages of broad-spectrum antibacterial property, fast action, good compatibility with enzyme and low toxicity, and is particularly applicable to the decay prevention of the remains in humid and other environments.

The present invention provide a catheter which exhausts a humor such as a hematoma, a brain fluid, and an encephalophyma smoothly without any infection, and be able to inject a hematoma resolvent while maintaining a constant brain pressure, and is inserted into an accurate operative portion in the cranial cavity using a brain stereotactic frame conveniently and easily. The catheter 100 includes a long tube 110 made of an atoxic, transparent and flexible material; a two-way fitting 160 having two channels and inserted into a rear portion of the tube through a fitting 120; second and third coupling members 140 and 150 selectively coupled to a branched channel of the two-way fitting 160; an injection member 170 including a needle portion 174 inserted into a rear portion of the third coupling member 150 through an inserting hole 153; and a fourth coupling member 180 including a seal member 181 and being inserted into a reception groove 171 formed in a rear portion of the injection member 170.

The invention discloses a repair method of corrupt remains. The method comprises the following steps: S1, putting the remains in an unfreezing tank, loading clear water to cover the remains, adding peroxyacetic acid with the diluted concentration of 0.2 to 0.5 percent according to the proportion of the water, then adding salt with the diluted concentration of 15 to 25 percent, finally adding camphor, soaking for 8 to 12h; S2, putting the remains in the S1 onto a moving bed, cleaning and scrubbing the body of the remains with a compound type preservative solution, and performing injecting corrosion prevention on chest, enterocoelia, cranial cavity, throat cavity, limbs, neck and head and face skin. By adopting the method to repair the remains, the tissue restoration effective time is short;the method is suitable for remains preservation, remains memorial farewell and last visitation, has high practicability, is environmentally friendly and harmless, is capable of restoring the distortional and color-changed remains caused by corruption, can enable the remains to restore to be clean and natural, the satisfaction rate of service objects is 100 percent, and good social benefit and economic benefit are obtained. After the method is widely popularized and used, the funeral service quality is improved, the mental stress of a client is reduced, and the psychological need of people ismet.

A system which includes a first sensor placed proximate to a perfusion field of an artery receiving blood which emanates from the cranial cavity is configured to monitor pulsations of the artery receiving blood which emanates from the cranial cavity artery. A second sensor placed proximate to a perfusion field of an artery which does not receive blood emanating from the cranial cavity and approximately the same distance from the heart as the first sensor configured to monitor pulsations of the artery which does not receive blood emanating from the cranial cavity. A third sensor placed distally from a heart is configured to monitor pulsations of a distal artery. A processing system responsive to signals from the first, second, and third sensors is configured to determine intracranial pressure.

The invention discloses a method for determining a craniotomy approaching channel through 3D modeling of medical images and belongs to the technical field of medicines. The method comprises steps as follows: a cranial cavity image of a patient is acquired; 3D modelling is performed on the cranial cavity image, and a 3D model of a cranial cavity is obtained, wherein the 3D model of the cranial cavity comprises a skull, blood vessel distribution in the skull and tumor; on the basis of the position of tumor, the position where craniotomy is performed formally is determined on the skull in the 3Dmodel of the cranial cavity; the relation between the position where craniotomy is performed formally and the position of tumor is determined with the position where craniotomy is performed formally as a datum point, and an approaching channel is constructed; the approaching channel is output. With the application of the method, before a doctor formally implements the craniotomy operation, the doctor can have a comprehensive knowledge about the craniotomy operation, the doctor is assisted in rapidly and accurately finding the tumor position, the operation time is shortened, and the operation risk is reduced; besides, when the doctor formally implements the craniotomy operation, the doctor is helped to determine the process of operation instruments, and the operation instruments can accurately reach the tumor position.

A non-invasive pressure monitoring system includes a first sensor placed proximate to a perfusion field of an artery receiving blood which emanates from the cranial cavity is configured to measure pulsations of the artery receiving blood which emanates from the cranial cavity artery and generate first output signals. A second sensor placed proximate to a perfusion field of an artery which does not receive blood emanating from the cranial cavity configured to measure pulsations of the artery which does not receive blood emanating from the cranial cavity and generate second output signals. A third sensor is configured to measure one or more physiological parameters of the human body and generate third output signals. A processing system responsive to signals from the first, second, and third output signals is configured to determine intracranial pressure.

A method and device for reducing the damaging effects of a blast or concussive event includes applying pressure to at least one jugular vein to reduce the egress of blood from the cranial cavity during the incidence of the concussive event. Reducing blood out flow from the cranial cavity increases intracranial pressure of the cerebrospinal fluid to reduce the risk of traumatic brain injury and injuries to the spinal column. Reducing blood out flow further increases the intracranial pressure, and thereby increases the pressure of the cochlear fluid, the vitreous humor and the cerebrospinal fluid to thereby reduce the risk of injury to the inner ear, internal structure of the eye and of the spinal column. In addition, increasing intracranial pressure reduces the likelihood of brain injury and any associated loss of olfactory function

The invention belongs to the signal processing technical field and provides a cranial cavity vibration detection method and device. The method includes the following steps that: vibration signals to be detected are acquired, and filtering processing is performed on the vibration signals, and Fourier transform is performed on the filtered vibration signals, and as a result, a frequency domain image of the vibration signals can be obtained; the largest energy value and the second largest energy value within cranial cavity vibration effective bands in the frequency domain image are obtained; and the vibration signals are determined as cranial cavity vibration signals when the largest energy value and the second largest energy value satisfy preset cranial cavity vibration conditions. With the cranial cavity vibration detection method and device of the invention adopted, detection of cranial cavity vibration can be realized, and the accuracy of cranial cavity vibration detection can be improved.