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Scavenger receptors are a group of receptors that recognize modified low-density lipoprotein by oxidation or acetylation. This naming is based on a function of cleaning: Scavenger receptors widely recognize and uptake macromolecules having a negative charge as well as modified LDL.
Monoclonal antibodies against human soluble scavenger receptor a and uses thereof
PendingCN122255280AImmunoglobulins against cell receptors/antigens/surface-determinantsTissue cultureAntiendomysial antibodiesScavenger receptor
The application discloses a monoclonal antibody for identifying human soluble scavenger receptor A, and the amino acid sequences of the heavy chain and the light chain variable region are shown as SEQ ID NO. 1 and SEQ ID NO. 5. A double antibody sandwich detection method is established by using the monoclonal antibody as a capture antibody, the whole operation time is shortened from the conventional 4 hours to 1.5 hours, the detection P / N value is significantly improved, the minimum detection limit reaches 15 pg / mL, and the detectable range is 15-7680 ng / mL. The method is suitable for human soluble scavenger receptor A detection.
Owner:ORIENTAL OCEAN (BEIJING) MEDICAL RES INST CO LTD +1