The invention provides a comprehensive real-time simulation platform for a large wind turbine generator, and the platform comprises the steps: building a wind model, a mechanical part model and a pneumatic model of the wind turbine generator through GH Bladed software, and carrying out the signal interaction through GH hardware test software, so as to achieve the simulation. An electrical part model of a wind turbine generator is constructed through RT-lab software, real-time calculation of a nanosecond-step motor and a three-level topology can be achieved, hardware-in-loop real-time simulation of a converter controller can be achieved, a main controller PLC operates a main control algorithm of the wind turbine generator, the converter controller operates a converter control algorithm, signal interaction is carried out among the model simulation, a main controller PLC and a converter controller through an ADS communication IO interface, and comprehensive real-time simulation tests such as starting of a control unit, grid connection, monitoring, protection, fault diagnosis, yawing, variable pitch, converter power instruction, shutdown, converter network side and machine test control, low penetration and high penetration control and the like can be carried out.