30 results about "Wound scar" patented technology

The invention relates to a prosthesis that can be implanted in the centre of wall wound scarring. The inventive prosthesis, which is intended for use in abdominal surgery, is provided with a geometric shape in the form of sheets that converge in dihedral angles. The sheets or planes are made from a synthetic biotolerated material in porous form with large pores. One of said planes is inserted into the centre of the scarring between the two aponeurotic surfaces to be joined. The other plane(s) of the prosthesis, which is perpendicular to the aforementioned plane, is arranged so as to overlap the aponeurotic edges of the edge of the section. The proliferation obtained around the prosthesis, in the scarring centre and close thereto, provides stress resistance greater than that obtained in standard closures, thereby greatly reducing the risk of hernias caused by a badly healed wound.

The present invention provides a complementary three-step dermabrasion system that provides treatment for skin conditions such as acne scars, wound scars, and other visually unappealing skin disfigurements, which constitutes the following, (1) Dermal Resurfacing with an adhesive composition, (2) Dermal Polishing with a polishing composition, and (3) Dermal Regeneration with a collagen-building and cell-proliferative composition.

The present invention provides a complementary three-step dermabrasion system that provides treatment for skin conditions such as acne scars, wound scars, and other visually unappealing skin disfigurements, which constitutes the following, (1) Dermal Resurfacing with an adhesive composition, (2) Dermal Polishing with a polishing composition, and (3) Dermal Regeneration with a collagen-building and cell-proliferative composition.

Skin remodeling is stimulated at the site of blemished skin using an ionic metal-peptide complex to diminish or remove the skin imperfection. The blemish can be a scar, especially surgical or wound scars, acne scars, keloid scars, and the like, or a skin tag, callus, benign skin mole, stretch marks, facial keratosis, thickened sunspots of the skin, or a vitiligo spot. The peptide-ionic metal complex is comprised of an ionic metal selected from copper(II), tin(II), tin(IV), and zinc(II), and salts thereof, and the peptide component can be a hydrolysis of casein, collagen, elastin, meat products, silk protein, or soybean protein, or a chemically synthesized dipeptide, tripeptide, tetrapeptide or the like which complexes with the ionic metal.

The invention discloses a preparation method of an antibacterial repairing type medical non-woven fabric. The preparation method is characterized by including: (1) opening: cleaning blend fibers in bacteria-free water for 2-3 times, and heating for opening; (2) combing to form a net: oscillating the blend fibers by ultrasonic waves with frequencies of 40 kHz and 25kHz, and settling to obtain a blend fiber net; (3) atomized water spraying: using pressurized atomized water to spray the front side and the reverse side of the blend fiber net; (4) drying: drying the blend fiber net in a low temperature after being sprayed by the atomized water; (5) preparing a bamboo fiber layer: preparing the dried blend fiber net into a bamboo fiber net layer according to the steps from (1) to (4); laminating by heat sealing: overlaying a tea fiber net layer with the bamboo fiber net layer, and adding medicament powder prior to laminating. The preparation method has the advantages that the prepared antibacterial repairing type medical non-woven fabric is uniform in thickness, high in stretchability, long in sterilizing effect lasting time and capable of healing a wound quickly and removing wound scars after being used.

The present invention provides methods for preventing or treating infections, especially bacterial infections, by administering selective inhibitors of ATP production to inhibit glycolytic enzymes, such as glyceraldehyde 3-phosphate dehydrogenase (GAPDH). As such, the present invention further provides methods for preventing or treating inflammation and sepsis associated with infections, as well as increased wound healing and decreased wound scarring.

The invention discloses a pure natural ointment for treating scalds and burns. The ointment is prepared through the following steps: preparing egg yolk oil, and preparing the ointment. The pure natural ointment makes up for the deficiencies in the prior art, is simple to prepare, and has substantial curative effects on scalds and burns, children's diaper rash, various types of dermatitis, and body surface ulcers. The ointment is a pure natural raw material, and a result of fifty years of clinic verification shows that the clinic cure rate and the effective rate of the pure natural ointment on patients with I and II grade burns and scalds and parts of patients with III grade burns and scalds respectively are 100%, and the pure natural ointment has the advantages of substantial effects, no wound scars and no untoward effects.

A surface suture device for skin wound has two supporting tapes arranged at both side of wound and a basic band with multiple sets of C-shaped suture thread guiders with C-shaped hole for limiting the suture thread to pass through it. Its advantages are uniform suture force and small residual scar.

The invention discloses application of a lavender oil formula preparation to skin scars. The application comprises the following steps: I, selecting materials; II, preparing a lavender oil formula preparation; III, performing mouse testing; IV, performing observation, and acquiring indexes; V, performing data comparison. By rubbing skin with lavender oil, a skin scar can be prevented; after a scalded part of a mouse is rubbed with the lavender oil, slight inflammation together with slight edema can be resulted, the wound at skin lesion can be clean at the seventh day, a medium amount of granulation tissue can be observed without exudation, the skin lesion is clean without crusta at the twenty-eighth day, the wound is completely healed, and hair grows out; with external application of the lavender oil, the level of an anti-inflammatory factor IL-10 in mouse serum can be increased, the inflammation of wounds can be relieved, expression of TGF-beta 1 can be remarkably improved, the activity of fibroblast can be improved, the ratio of type I / II procollagen can be adjusted, wound scars can be inhibited, and in addition, scar tissue can be repaired.

The invention discloses a preparation method of an antibacterial repairing type medical non-woven fabric. The preparation method is characterized by including: (1) opening: cleaning blend fibers in bacteria-free water for 2-3 times, and heating for opening; (2) combing to form a net: oscillating the blend fibers by ultrasonic waves with frequencies of 40 kHz and 25kHz, and settling to obtain a blend fiber net; (3) atomized water spraying: using pressurized atomized water to spray the front side and the reverse side of the blend fiber net; (4) drying: drying the blend fiber net in a low temperature after being sprayed by the atomized water; (5) preparing a bamboo fiber layer: preparing the dried blend fiber net into a bamboo fiber net layer according to the steps from (1) to (4); laminating by heat sealing: overlaying a tea fiber net layer with the bamboo fiber net layer, and adding medicament powder prior to laminating. The preparation method has the advantages that the prepared antibacterial repairing type medical non-woven fabric is uniform in thickness, high in stretchability, long in sterilizing effect lasting time and capable of healing a wound quickly and removing wound scars after being used.

A non-human animal model, method, spring, and kit for testing agents for treating wound scarring. The non-human test animal has a wound in a skin surface thereof, the wound having a perimeter edge; and a garter spring attached to the skin surface of the test animal in a position outside of the perimeter edge of the wound. The garter spring optionally has one or more bands for constricting the force exerted by the coil of the garter spring.

The present invention provides methods for preventing or treating infections, especially bacterial infections, by administering selective inhibitors of ATP production to inhibit glycolytic enzymes, such as glyceraldehyde 3-phosphate dehydrogenase (GAPDH). As such, the present invention further provides methods for preventing or treating inflammation and sepsis associated with infections, as well as increased wound healing and decreased wound scarring.

The invention discloses a care solution for nursing after hemorrhoids resection. The care solution is characterized by being prepared form the following medicinal materials in parts by weight: 12-15 parts of keel, 8-12 parts of oiltea camellia flower, 8-12 parts of lysimachia hypericoides hemsl, 8-12 parts of folium cycas, 12-15 parts of Japanese beauty-berry, 8-12 parts of gynura divaricata, 12-15 parts of hyperforin perforatum, 18-20 parts of conespike flemingia leaves, 8-12 parts of common cockscomb leaves, 12-15 parts of abroma angusta, 12-15 parts of semi-pinnated brake herb, 8-12 parts of longstamen loosestrife herb, 8-12 parts of elsholtzia blanda benth, 15-18 parts of rheum lidjiangense, 15-18 parts of henry hemsleya root and 15-18 parts of ligustrum sinense. According to the liquid medicine prepared by the formula disclosed by the invention, local hemodynamic disorders can be effectively improved; the contraction state of ani sphincter is relieved; the pain is relieved; tissue regeneration and wound healing of an incision are promoted; and wound scars are reduced.

The invention discloses a scald powder, which is composed of powdery raw materials vitamin B2, chloramphenicol and dexamethasone, and the weight ratio among the components is 1-4:2-5:1-3. In order to improve the anti-inflammatory effect, 1-3 parts by weight of powdery raw material sulfadiazine is also added. The medicine of the invention is an external medicine, and the preparation method is simple, and the raw materials of each component are crushed and mixed. The medicine of the present invention has the advantages of fast recovery of poisonous water for treating burns and scalds, strong ability of dispelling poisons, and rapid growth of flesh and skin. For small-area scalds and burns, it can be cured after two times of medication; for large-area scalds and burns, after two to three times of medication, the poisonous water will no longer flow, and the wound will scab. . The medicine of the present invention has an effective rate of 100% in treating various types of burns and scalds, a cure rate of 100%, no side effects, no scratches on the flesh, no scars, unblocked pores and intact skin after recovery, and is effective in treating bruises, bruises, and sores. Same effect.

The invention relates to a formula of a traditional Chinese medicine for treating frostbite. The traditional Chinese medicine comprises 37-41g of rhizoma coptidis from Sichuan of China, 25-31g of phellodendron, 39-46g of garden burnet, 42-47g of Chinese gall, 20-30g of potato, 250-300g of honey and 200-250g of Vaseline. Through use of the traditional Chinese medicine for 5-10min, bleeding and a pain of a wound are stopped. Through use of the traditional Chinese medicine for about 1 week, frostbite can be cured. The traditional Chinese medicine can effectively prevent and control wound infection and cross infection, has no adverse side effect, and avoids wound scar after wound healing.

The present invention is concerned with a composition and in vitro method for generating a desired cell type and / or tissue type from hair follicular stem cells. The composition and in vitro method are particularly suitable for generating an autologous desired cell type and / or tissue type. Furthermore, the composition and method are especially efficient and suitable for use in the context of cosmetic cell and / or tissue transplantation in recipient areas of a subject experiencing cell and / or tissue loss caused by, for example, a wound, scar, burn injury, tissue degeneration, and aging. The composition and in vitro method are also suitable to circumvent complications related to infections and / or immune rejection of a cosmetic cell and / or tissue implant or graft.

Skin remodeling is stimulated at the site of blemished skin using an ionic metal-peptide complex to diminish or remove the skin imperfection. The blemish can be a scar, especially surgical or wound scars, acne scars, keloid scars, and the like, or a skin tag, callus, benign skin mole, stretch marks, facial keratosis, thickened sunspots of the skin, or a vitiligo spot. The peptide-ionic metal complex is comprised of an ionic metal selected from copper(II), tin(II), tin(IV), and zinc(II), and salts thereof, and the peptide component can be a hydrolysis of casein, collagen, elastin, meat products, silk protein, or soybean protein, or a chemically synthesized dipeptide, tripeptide, tetrapeptide or the like which complexes with the ionic metal.

The invention discloses a preparation method of a composition for inhibiting wound cicatrix healing, comprising the following steps: (1) weighing L-selenium-methylselenocysteine ​​and transparent uric acid, and measure the ultrapure water according to the ratio, and dissolve the weighed L-selenium-methylselenocysteine ​​in the ultrapure water, stir, shear, and vibrate with an ultrasonic mixer Shake or vortex until L-selenium-methylselenocysteine ​​is completely dissolved in ultrapure water, then add the weighed hyaluronic acid, and swell at room temperature for 1-2 days to obtain the composition stock solution; ( 2) Under sterile conditions, pass the composition stock solution through a 0.22 μm microporous membrane to sterilize, subpackage under sterile conditions after sterilization, and store at 2-8°C to obtain the antibacterial Composition for wound cicatrix healing. The composition for inhibiting wound cicatrix healing prepared by the invention can effectively reduce wound cicatrix healing, and can reduce the pigmentation of the wound site in the wound shaping stage.

The invention discloses functional sponge for promoting wound healing and reducing wound scar formation as well as a preparation method and application of the functional sponge. The method comprises the following steps: dissolving hyaluronic acid in water with the pH value of 4.5-5.5, and stirring to obtain a hyaluronic acid glue solution; adding EDC and NHS, carrying out a stirring reaction in a dark place, then adding the chitosan oligosaccharide-europium complex, continuing the reaction, injecting a reaction solution into a mold, and continuing the reaction in a shaking table to obtain a cross-linked hyaluronic acid gel; freezing and drying to obtain the hyaluronic acid / chitosan oligosaccharide-europium functional sponge, namely the functional sponge for promoting wound healing and reducing wound scar formation. The method is mild in experimental condition and simple and convenient in step, the chitosan oligosaccharide-europium complex is used as a cross-linking agent, chitosan oligosaccharide with an anti-inflammatory effect and europium element with a vascularization promoting function are introduced at the same time, and the obtained HA-CE is obvious in anti-oxidation, anti-inflammatory, vascularization promoting and fibrosis reducing effects and has a good application prospect.

The invention discloses a dressing for promoting wound healing. The dressing is prepared from the following raw materials: 3-15 percent of bioactive glass, 0.5-5 percent of nicotinamide, 0.01-1 percent of lyophilizing thrombin powder, 1-60 percent of glycerinum and 1-50 percent of gelatin. According to the dressing for promoting wound healing and a method for preparing functional cavernosum by applying the dressing, the dressing for promoting wound healing is fixed in a functional cavernous body to perfectly solve the medical problem that functional cavernosum is difficult to promote healing of wounds which are difficult to heal, has the advantages of promoting tissue regeneration, inducing epithelialization, reducing wound scars and the like, can be used for effectively stopping bleeding,adsorbing fluid oozed from a wound and providing a wet and transparent environment to a wound, is favorable to wound healing, can perfectly solve the problem of replacing skin-grafting for managementof wounds which cannot perform autologous healing, and can achieve the effect of promoting healing wounds which are difficult to heal after directly acting on the wounds.

The invention discloses an amniotic membrane biological preparation and a preparation method thereof. The amniotic membrane biological preparation adopts the human and animal decellularized amniotic membrane covered with a platelet-rich factor plasma preparation, freeze-dried and irradiated, and stored in low-temperature refrigeration, and is used for repairing clinical skin damage treat. The amniotic membrane biological preparation can significantly improve the healing time of the wound and reduce the scar formation of the wound, and is an industrializable biological preparation with great clinical application prospects.

The present invention is concerned with a composition and in vitro method for generating a desired cell type and / or tissue type from hair follicular stem cells. The composition and in vitro method are particularly suitable for generating an autologous desired cell type and / or tissue type. Furthermore, the composition and method are especially efficient and suitable for use in the context of cosmetic cell and / or tissue transplantation in recipient areas of a subject experiencing cell and / or tissue loss caused by, for example, a wound, scar, burn injury, tissue degeneration, and aging. The composition and in vitro method are also suitable to circumvent complications related to infections and / or immune rejection of a cosmetic cell and / or tissue implant or graft.

The invention relates to an inverse opal hydrogel microcarrier for treating wounds. The inverse opal hydrogel microcarrier comprises 3.6-4.5 wt% of cyclodextrin, 3-5 wt% of polyacrylic acid and 3-5 wt% of agar, the inverse opal hydrogel microcarrier has pores with an average particle size of 100-300 nm, and tretinoin is loaded in the pores. The inverse opal hydrogel microcarrier can load tretinoin, is helpful for the tretinoin to improve wound scars, and has the advantages of convenience in use and good scar removal effect.

The invention discloses a hydrogel composition for inhibiting scar formation, which is prepared from the following raw materials in parts by weight: 1 to 10 parts of beta-glucan, 1 to 10 parts of chitin, 100 to 500 parts of ultrapure water and 2 to 30 parts of cross-linking agent. The hydrogel composition disclosed by the invention is a beta-glucan-chitin hydrogel composition, has the characteristics of low toxicity, good biocompatibility, biodegradability and the like, can be used for remarkably inhibiting formation of wound scars, and can be used as an excellent candidate material for inhibiting formation of the wound scars. The invention further discloses a preparation method and application of the hydrogel composition for inhibiting scar formation.

The invention discloses a medical hydrogel antibacterial dressing for preventing new wound scars from forming, which comprises a hydrogel hot compress material main body, the inner side surface position of the hydrogel hot compress material main body is fixedly connected with a hydrogel dressing, the inner side position of the hydrogel dressing is provided with a moisture absorption and viscosity reduction protective film, and the moisture absorption and viscosity reduction protective film is fixedly connected with the hydrogel dressing. One side of the hydrogel hot compress material main body is fixedly connected with a first dustproof pad, and the other side of the hydrogel hot compress material main body is fixedly connected with a second dustproof pad. The medical hydrogel antibacterial dressing for preventing new wound scars from forming is high in biocompatibility, not prone to causing stimulation and allergy, skin-friendly, bacteriostatic, perfectly attached to skin, high in water content, constant in temperature and humidity, capable of creating a moist environment suitable for cell growth and new cell wandering, capable of achieving wet-type healing, capable of achieving mild layered long-acting release due to the adoption of a 3D net layer structure and capable of achieving long-acting healing. The content of effective components is higher, a skin protection film is formed, various shapes can be formed, the wound change situation can be observed, and the liquid absorbency is high.

The invention discloses a traditional Chinese medicine formula for treating scar hyperplasia, and relates to the technical field of medicaments. The formula is characterized in that the formula contains two medicinal materials of dark plum and oyster, wherein a weight ratio of dark plum to oyster is 1: 2; dark plum is carbonized and then is grinded into fine powder; and oyster is calcined and then is grinded into fine powder. Because of the combined use of two sour and saline experiential prescriptions adopting respectively dark plum and oyster as raw materials, wherein dark plum has a sour and astringent taste and functions of astringing, softening hardness, eliminating swelling and astringing sores and the modern medicine research shows that oyster has a saline taste and functions of easing pain, diminishing inflammation, compacting capillary vessels and reducing blood vessel permeability, the traditional Chinese medicine formula for treating scar hyperplasia is reasonable and has obvious effects of treating burn scars and wound scars.

The invention discloses a portable irrigating device for bleeding wound care. Round through holes are formed in the upper wall surface of a circular tank body, a water storage tank is installed in the circular tank body, a micro pump is installed in the water storage tank, a first water outlet is formed in the side wall surface of the water storage tank, a first water outlet tube is installed in the first water outlet in an embedding mode, one end surface of the first water outlet tube is connected with the micro pump in a lapping mode, a second water outlet is formed in the side wall surface of the water storage tank, a second water outlet tube is installed in the second water outlet in an embedding mode, a first control valve is installed on the first water outlet tube in a sleeving mode, a first sprayer is installed on one end surface of the first water outlet tube, a water outlet with a filter mesh is formed in the circle center of the lower end of the first sprayer, and a sector sprayer, a spiral sprayer and a duckbill sprayer are arranged in the peripheral direction of the first sprayer. According to the device, the structure is novel, operation is convenient, combination of multiple irrigation modes is achieved, different irrigation modes can be selected on the basis of different wounds, and the effect of wound irrigation is good.