The invention discloses a high-yield trellis-erection cultivation method of subprostrate sophora seeds. The method comprises the steps of bedding, field planting, trellis erection, branch guiding to trellises, flower and fruit preservation, seed harvesting and pruning and fertilizer supplementation; from March to April, diagonal field planting is conducted; from May to July of the second year after field planting, the cultivation trellises are erected among subprostrate sophora rows; in the second year and third year after field planting, on the first ten days of April, a mixed aqueous solution of gibberellin, brassin and high-potassium foliar fertilizer is sprayed to flower branches, on the middle ten days of May, a 20% chlorantraniliprole suspension aqueous solution is sprayed to whole plants, and from the middle and last ten days of May to the first ten days of June, the flower branches are pruned. According to the method, by additionally arranging the cultivation trellises among the subprostrate sophora rows, the branches of subprostrate sophora grow transversely along the cultivation trellises, and dense branches and lodging are avoided; meanwhile, in cooperation with pruningof the flower branches, fertilizer supplementation and pest prevention and control, the flower and fruit setting rate of subprostrate sophora is increased, and the high yield of the subprostrate sophora seeds is achieved.