The invention discloses a cavity sterilizing device used for surgical operation. The cavity sterilizing device comprises a box, a door board is connected to the front side of the box through a hinge,a fluid outlet tube is installed at the top end of the box, the bottom end of the fluid outlet tube extends to the top end of an inner cavity of the box, a fluid storage bag is placed in the center ofthe bottom end of the inner cavity of the box, the top end of the fluid storage bag and the bottom end of the fluid outlet tube are installed together, one end of a hose is installed at the top end of the fluid outlet tube, a spray nozzle is installed at the other end of the hose, a lantern ring is installed on the outer wall of the part, located at one end of the spray nozzle, of the hose, a hook is installed at the top end of the rear side of the box, and the lantern ring sleeves the outer wall of the hook to suspend the hose. Through the cavity sterilizing device used for surgical operation, a cavity of a wound of a patient can be conveniently sterilized by a medical worker, the working difficulty of the medical worker is lowered, the working efficiency of the medical worker is improved, meanwhile, the amount of discharged sterilizing fluid is controlled, the sterilizing fluid is prevented from being wasted, and popularization is easy.