The invention relates to a dyeing method of a nylon / spandex blended fabric. The method comprises the following steps: pretreating the nylon / spandex blended fabric; then carrying out dyeing in the samebath, adding an acid dye, a leveling agent and acetic acid in the dyeing process, adjusting the pH value, carrying out heating, heat preservation and dyeing, adding a disperse dye, a dispersing agentand ammonium sulfate after cooling, adjusting the pH value, and carrying out heating, heat preservation, dyeing, cooling and water washing; and carrying out color fixation. According to the method, an acid dye and a disperse dye are used for one-bath two-step dyeing, the process is simple, and large-scale production can be realized by adopting conventional dyeing equipment.