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75results about How to "High Sensitivity Features" patented technology

Integrated photon crystal double waveguide back coupling fluid refractive index sensor

The invention belongs to the photoelectronic technical field, characterized in that: it adopts electron beam exposure and dry-etching process to form a photon crystal double-waveguide structure on semiconductor, where the two ends of the photon crystal waveguide are connected with light guide connection light waveguides and it removes part of the sacrificial layer by wet etching process to form a bridge support structure. By reverse coupling action of the photon crystal double waveguide, the light of evenly symmetric transmission mode cross over frequency can be reversely coupled from straight-through waveguide into coupling waveguide so as to cause the transmission spectrum of the straight-through waveguide has obvious hollows. When the detected fluid fills periodical holes of photon crystal or upper and lower spaces of the photon crystal layer, dispersion characteristic of the transmission mode in the photon crystal double waveguide is changed, or changed by external force, which can cause variation of evenly symmetric transmission mode cross over frequency so as to cause variation of transmission spectrum of the straight-through waveguide, thus implementing microflow refractivity detection and sensing of high sensitivity and integrated photon crystal structure.
Owner:TSINGHUA UNIV

Primer middle sequence interference PCR (Polymerase Chain Reaction) technology

The invention relates to a primer middle sequence interference PCR (Polymerase Chain Reaction) technology. The improved PCR technology is characterized in that one segment of relatively non-complemented or same-sequence basic group primer molecules in the intermediate domain of primers perform the antisense interference inside and outside so as to competitively destroy the polymerization among the primers to selectively inhibit the primer dimer (PD) from being amplified. For the interference of the intermediate domain of the primers, based on the primers optimally selected by the conventional design principle, the technology that the intermediate domain (ID) of a pair of the primers are in parallel but are not complemented with each other or are in the same sequence or/and the technology that ID antisense oligonucleotides (Oligo) are added into the primers to perform the interference action or/and the Oligo antonymy is carried out in the primer molecules via the ID so as to perform the interference action are adopted, or the combined technology of the three types of the technologies is adopted. As a result, only the ID of the primers is interfered while the target specific amplification is not influenced; the combining force acting on the minority of base-group pairing hydrogen bonds at the tail end and the base-group hydrogen bonds outside the tail end due to the action of the primers is dispersed to a maximum extent, so that the PD is selectively inhibited. Therefore, the PD accumulation in the PCR system is avoided. If the mineral oil is additionally used, the sealed primers can slowly release the hot starting and the UDG pretreatment so as to prevent aerosol glue as a byproduct of the PCR system from causing the pollution. Consequently, the nucleic acid is amplified reliably and the real-time fluorescence PCR is quantified accurately.
Owner:珠海市坤元科技有限公司

Resistance-changing capacitance-changing composite two-dimensional strain sensor and preparation method thereof

The invention discloses a resistance-changing capacitance-changing composite two-dimensional strain sensor and a preparation method thereof. The resistance-changing capacitance-changing composite two-dimensional strain sensor proposed by the invention is of a three-layer structure including an upper plate, an insulating dielectric layer and a lower plate of of a parallel plate capacitor in design.The conductive materials for the upper plate and the lower plate are selected from metals having a micro/nano structure, a carbon conductive materials or metal-carbon mixed conductive materials, thebipolar plate patterns are designed in a serpentine shape, and the upper plate and the lower plate of the capacitor are simultaneously used as a resistance-changing tensile strain sensor. The resistance-changing capacitance-changing composite two-dimensional strain sensor of the invention detects a tensile strain in a horizontal direction through a capacitance-changing phenomenon, detects a tensile strain in ae vertical direction through a resistance-changing phenomenon, and detects a tensile strain in a two-dimensional orthogonal direction by using the resistance-changing capacitance-changingcomposite form, so as to have flexible and tensile characteristics; and the resistance-changing tensile sensor adopts a permeable conductive network structure and has good sensitivity.
Owner:UNIV OF ELECTRONICS SCI & TECH OF CHINA

Surface stress sensitization method for improving resonance type ultra-thin cantilever beam transducer sensitivity

The invention relates to a method for improving surface stress sensitivity of a resonant ultrathin cantilever beam sensor, and belongs to the technical field of micro-mechanical sensing. The method is particularly characterized in that self-assembling monomolecular sensitive films capable of identifying selection specificity can be grown on the upper surface and the lower surface of an ultrathin resonant cantilever beam sensor; after specificities of sensitive molecules and target molecules to be detected are combined, interaction among the target molecules generates surface stress on the surfaces of the cantilever beam; and the combined action of the upper surface stress and the lower surface stress causes change of elasticity coefficient of the cantilever beam so as to change inherent resonance frequency of the cantilever beam, and achieve detection for the target molecules through measuring the change of the resonance frequency. Compared with the prior method for sensitivity test by using a mass adsorption method, the method for improving the surface stress sensitivity can carry out biochemical trace test, and the sensitivity can be improved by one order of magnitude. The method has the characteristics of simple principle, high sensitivity and easy realization.
Owner:SHANGHAI INST OF MICROSYSTEM & INFORMATION TECH CHINESE ACAD OF SCI

Surface plasma excimer slow-ray gyroscope and method for producing the same

A surface plasmon slow-light gyroscope and the preparation method thereof are provided. The surface plasmon waveguide transmission signal is adopted so as to realize the high sensitivity of the slow-light gyroscope. The surface plasmon slow-light gyroscope includes an interference type and a resonance type surface plasmon waveguide optic gyroscopes, wherein the interference type waveguide structure gyroscope is composed of an open-ring waveguide and the resonance type waveguide structure gyroscope is composed of a closed-ring waveguide. The surface plasmon slow-light gyroscope is characterized in that light-wave signal is replaced by the surface plasmon wave and optical waveguide loop is replaced by the surface plasmon waveguide loop with a structure of metallic nanometer defect, nano-particle, nano-wire, nano-film or nano-lattice. The preparation process is described as follows: a. the open-ring metallic nano-wire is introduced to the interference type surface plasmon slow-light gyroscope, so as to form the surface plasmon waveguide structure, and further form the signal channel in the optical gyroscope; and b. the closed-ring metallic nano-wire is introduced to the resonance type surface plasmon slow-light gyroscope, so as to form the surface plasmon waveguide structure and further form the signal channel in the optical gyroscope.
Owner:SOUTHEAST UNIV
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