The invention relates to a production method of a high-efficient multielement compound/mixed fertilizer, which comprises the steps: firstly, the adjustment of chemical components in boric sludge is carried out, a certain amount of boric sludge which is naturally withered with the water content less than 5 percent is taken, sulphuric acid of 50 to 98 percent is continuously and evenly added into the sludge while stirring at normal temperature to lead the pH value of the boric sludge to between 6 and 7, a boric sludge base fertilizer is obtained for later use after drying and crushing; and then, the base fertilizer is adjusted towards boric fertilizer and carried out with pelleting: a certain amount of urea, monoammonium phosphate, potassium chloride or potassium sulphate is added into the boric sludge base fertilizer sequentially, then pelleting, drying and sieving are carried out after evenly mixing, the mixture is cooled to below 40 DEG C when the water content is less than 4 percent, at the moment, the pH value is between 6.5 and 7.5, and packing is carried out to get the finished compound/mixed fertilizer. By utilizing the waste residue from the production of borax and carrying out acidizing, insoluble elements of B, Mg, Ca and the like are transformed to soluble substances, thus fundamentally substituting compounds separately added with monomers of Mg, Ca and the like, therefore, the fertilizer is applicable to various crops and soils.