The invention discloses a solid-liquid four-phase horizontal spiral centrifuge, which belongs to the field of centrifugal separation equipment. The solid-liquid four-phase horizontal spiral centrifuge comprises a rotary drum, wherein the rotary drum comprises a first separation chamber, a second separation chamber and a separation plate, the first separation chamber comprises a conic section and a straight section, a spiral conveyor is arranged in the first separation chamber, an end cover is fixedly connected to the end of the second separation chamber, and liquid holes at different distances from the axis are radially formed in the end cover; the separation plate is arranged between the first separation chamber and the second separation chamber, an overflowing hole which is used for communicating the first separation chamber with the outer wall of the rotary drum and a communicating hole which is used for communicating the first separation chamber with the second separation chamber are formed in the separation plate, and the distances between one end, which is located in the first separation chamber, of the overflowing hole and the axis as well as between one end, which is located in the first separation chamber, of the communicating hole and the axis are different; and the end cover comprises the separation plate and an outer cover which is fixedly connected to the separation plate, and a cavity is formed between the separation plate and the outer cover. Compared with the prior art, the solid-liquid four-phase horizontal spiral centrifuge has the beneficial effects that solid-liquid-liquid-liquid four-phase separation is realized, the separation diversity is increased, the product quality and the production efficiency are increased, and the cost is reduced.