The invention provides a thermal resonance fusion engine, and belongs to the technical field of engines. The thermal resonance fusion engine comprises an internal expansion part, a Sterling engine, a steam piston, a steam turbine and a gas turbine; turbine air jetting, punching air jetting and a rocket type are achieved; gas and liquid working media, and an closed or opened cycle are adopted based on a thermal resonance fusion stack; a standardized, modularized and serial design is adopted; fossil fuel is not used and oxygen is not needed in an operation process; an operation mode that only fusion fuel is input and mechanical power and a pollution-free fusion product are output is realized, and long-period, safe, stable and economic operation is realized. A principle technology, industrial manufacturing and large-scale industrialization are all feasible. The structure is simple. No radiation is formed outside a shielding layer. A plurality of thermoelectricity and power sources can be provided at the same time. The thermal resonance fusion engine can be enlarged or miniaturized. The thermal resonance fusion engine can be used as a mini-size, small-size, middle-size or large-size engine for being widely applied to vehicles, ships and various machines. The thermal resonance fusion engine can be operated for ultra-long time. The thermal resonance fusion engine can provide green, safe, cheap and sufficient mechanical power to development of economic society and civilization, and is especially suitable for long-distance and long-time comprehensive application.