The invention provides an automatic adjusting system for indoor air quality. The automatic adjusting system comprises a central control system, a temperature regulating system, a humidity regulating system, a self-adaptive environment regulation and control information acquisition system, a ventilation supply system and a sterilization system. The central control system is electrically connected with the temperature regulating system, the humidity regulating system, the self-adaptive environment regulation and control information acquisition system, the ventilation supply system and the sterilization system, and is used for controlling the temperature regulating system, the humidity regulating system, the self-adaptive environment regulation and control information acquisition system, theventilation supply system and the sterilization system to operate.