The invention discloses a high salinity wastewater treatment system, which comprises an incinerator, a dryer, a drying tower, a flue gas treatment system, a smoke exhaust fan and a discharge cylinder,the incinerator comprises a feed port and a discharge port, one side of the feed port is provided with a cloth belt conveyor and a screw conveyor, the discharge port is sequentially connected with aflue gas dust settling tower and a high temperature polyester cotton dust remover, and the high temperature polyester cotton dust remover is connected with the dryer. the drying machine comprises a high-salinity wastewater feeding hole, a flue gas inlet and a flue gas outlet, one side of the drying tower is connected with the flue gas outlet, one side, far away from the drying machine, of the drying tower is connected with a cyclone dust collector and a bag type dust collector, the bag type dust collector is used for introducing dust-removed gas into the flue gas treatment system, and the fluegas exhaust fan comprises an air inlet and an air outlet. The air inlet is connected with the flue gas treatment system, and the air outlet is connected with the discharge cylinder. According to thehigh-salinity wastewater treatment system, a whole set of circulation is formed, the heat efficiency of high-salinity wastewater drying is greatly improved, integrated treatment of high-salinity wastewater drying, incineration and waste gas is achieved, and regeneration and utilization of high-salinity wastewater are greatly met.