The invention provides an impregnation method of non-woven fabric, which comprises the following steps of: providing the non-woven fabric made of double-component composite fiber, wherein the double components are polyester component and polyamide component; using framework parts arranged in a radioactive way and splinter parts filled among the framework parts to form the non-woven fabric, wherein the splinter parts and the framework parts are respectively formed by the double components; carrying impregnation treatment on the non-woven fabric by using polyvinyl alcohol impregnation liquid, and obtaining first impregnation base fabric; then, carrying out impregnation treatment by using polyurethane impregnation liquid, and obtaining second impregnation base fabric, wherein the polyurethane impregnation liquid comprises the components based on mass concentration: 12-20 percent of polyurethane, 1-3.2 percent of impregnation auxiliary agent and balance DMF; and finally, leading the second impregnation base fabric to enter coagulating liquid for coagulating, water washing and drying. By adopting the method, the impregnation treatment can be carried out on the non-woven fabric, so that the double-component composite fiber can be reserved inside the leather, the double components can be prevented from being adhered with the leather, and the finally obtained PU synthetic leather not only has stiffness of terylene, but also has softness of nylon.