27 results about "Muscle layer" patented technology

The present invention relates to an artificial digestive tract tissue for training in endoscopic submucosal dissection (ESD) and a method for manufacturing the same. Specifically, the invention relates to an artificial digestive tract tissue configured to mimic the mucosal layer, submucosal layer, and muscle layer constituting the human digestive tract tissue in a multilayer structure, such that swelling occurs upon liquid injection and a color change occurs due to changes in salt concentration, and to a casting and curing-based hydrogel molding process for manufacturing the same. According to the present invention, the problems associated with existing animal tissue-based ESD training simulators can be resolved, repeated use is possible, and training tailored to the structural characteristics of specific organs (stomach, large intestine, small intestine, etc.) is possible.

The present invention provides a medical device for forming an opening channel or access passage between body tubular lumens. [Solution] The present invention relates to a device that uses an elongated body, a proximal holding portion, and a distal holding portion to bring the muscle layers of a first body lumen and a second body lumen into contact and to form a long-term or permanent opening or access channel between them. The medical device comprises an elongated body that forms a lumen and includes a proximal portion, a distal portion, a certain length, and a certain diameter, wherein the elongated body 310 may have an elongated tubular form (e.g., a restrained form, an unexpanded form, or a transport form) and a retracted form (e.g., an unrestrained form, an expanded form, or an unfolded form) in which the proximal portion 312 expands radially into the proximal holding portion 314 and the distal holding portion 322 expands radially into the distal holding portion 324, with a cylindrical saddle portion 328 extending between them.

The invention discloses a kirschner wire sleeve device for muscle layer expansion, which relates to the technical field of orthopedic surgery and comprises a kirschner wire, an expansion sleeve, a protective layer and a traction rod. The expansion sleeve is composed of a support and an expansion layer, a guide ring is arranged in the middle of the support, symmetrical connecting frames are arranged on the outer side of the guide ring, the expansion layer is sleeved outside the guide ring, and one end close to a skeleton is of an involute pipeline structure. After the Kirschner wire fixes the bone, the guide ring slides towards the bone along the Kirschner wire, the involute pipeline structure of the expansion layer enters the space between the Kirschner wire and the muscle layer, and the muscle layer is pushed away outwards to form an operation space. The protective layer can reduce direct friction between the muscle layer and the expansion layer, and the lubricant arranged in the protective layer can assist operation; the traction rod can stably control the expansion layer to be opened. The device is made of a biocompatible material and is provided with a buffer structure, the operation space can be flexibly adjusted, the operation safety, adaptability and efficiency are effectively improved, and the use pain point of a traditional kirschner wire sleeve device is solved.

The invention discloses an intrauterine intelligent regulation and control auxiliary reinforcing device, belongs to the technical field of intrauterine device fixing, and aims to solve the problems that a common intrauterine device is worn in a free mode, the risk that the intrauterine device falls off automatically is caused, and displacement is easily caused due to insufficient installation stability. A first pinching ball is pressed to enable a driving rod to push a sliding plate forwards, the sliding plate enables a first needle head to stretch out of a second sliding groove and to be inserted into a uterine cavity muscle layer in a Y shape, the two ends of a first fixing line are brought into the muscle layer during insertion, then a second pinching ball is pressed to enable the first needle head to retract, and when the first needle head retracts, the first needle head is fixed. Line knots at the two ends of the first fixing line are separated from the first needle head from the containing part and the groove and left in the muscular layer to complete fixing of the contraceptive ring, and operation is easy and convenient.

The invention relates to the technical field of biology and new medicine, discloses an experimental method for modeling a rat for treating uterine diverticulosis, and aims to overcome the defects that in the prior art, outer longitudinal muscle fibers and inner annular muscle fibers of uterus are not distinguished, only muscular layers are extensively scraped, and the difference between the degree of inflammation under serosal and the degree of inflammation between the muscular layers after clinical operation is difficult to reproduce. According to the method, 11-12-week-old SPF-grade SD female rats are selected, muscle layer fibers are recognized under the assistance of a microscope, outer 2 / 3 longitudinal muscle fibers are preferentially removed, inner 1 / 3 annular muscle fibers are reserved, lipopolysaccharide layered injection is matched, and the model is constructed in combination with standard postoperative treatment. And a reliable animal model can be provided for meverticulum pathological mechanism research and therapeutic schedule evaluation.

The application discloses a kind of simulation dinosaur three-dimensional modeling optimization method and system, method constructs rigid body skeleton system based on Lagrange dynamics;According to the muscle layer of super-elastic material of anatomical attachment point, the displacement field is calculated using position-based dynamics method;Skin layer is constructed outside, Cauchy stress is projected to grid vertex, and wrinkle and scale texture are dynamically generated according to principal strain;The grid simplification degree and physical simulation accuracy of corresponding area are dynamically adjusted by calculating perceptual importance weight;Establish the quadratic programming problem with anatomical constraint to realize motion reorientation and angular momentum distribution;And construct deformation prediction cache model to carry out online constraint correction.The application realizes the unity of high-precision biological feature restoration and high-efficiency real-time rendering.

The application provides application of a DPP-4 inhibitor in preparation of a medicine for preventing and / or treating digestive tract stenosis, and belongs to the technical field of medicines. Based on morphological performance of stenosis segment esophageal tissue outer membrane scar fibrosis, it is found that a DPP-4+ fibroblast subpopulation in stenosis segment esophageal outer membrane fibrosis hyperplasia tissue is obviously highly expressed. The DPP-4 inhibitor can prevent and treat refractory stenosis after esophageal ESD operation through anti-inflammatory and anti-fibrosis effects on stenosis segment esophageal outer layer tissue, and is a powerful supplement to the current esophageal ESD postoperative stenosis which focuses on intraluminal prevention and treatment of esophageal submucosa and part of inherent muscle layer scar fibrosis.

The application provides a Mirena ring disc buckle puncture fixing clamp and belongs to the technical field of medical devices. The clamp comprises a hollow clamp rod, one end of the hollow clamp rod is provided with an energy storage mechanism, one side of the energy storage mechanism is provided with a puncture clamp assembly, and the puncture clamp assembly is single-clamp type or double-clamp type. The puncture clamp assembly is used for clamping and taking the Mirena ring disc buckle before an operation cavity is established in the uterine fundus muscle layer, and the puncture clamp assembly is accommodated in the cavity for restraint, so that the disc buckle and the tail wire are dragged into the uterine fundus muscle layer while the operation cavity is established. After the cavity is established, the energy storage mechanism is released, the puncture clamp assembly is driven to open the cavity by the traction assembly, so that the disc buckle and the tail wire are directly embedded in the uterine fundus muscle layer. Only one step is needed to complete the disc buckle embedding operation, the operation mode is simplified, the operation time is saved, and the risk of injuring normal tissues around the operation area when the disc buckle is embedded in the uterine fundus muscle layer for the second time is avoided.

The invention relates to the cross technical field of artificial intelligence, digital twinning, biomechanics and the like, in particular to an AI Agent construction method based on motion digital twinning and deep motion data analysis, and the method comprises the following steps: collecting motion data of a user, calculating joint angles and displacements at each moment, calculating moments borne by joints, and obtaining motion data of the user; then, the activation degree and muscle force of each muscle in the model at each moment are solved by taking the minimum muscle activation quadratic sum as a target, then heel landing and tiptoe off-ground events are recognized, a feature time sequence is obtained, distance features with training set samples are calculated and embedded into a target low-dimensional space, and embedded features are obtained; and generating personalized feedback information according to the embedded features. Therefore, the problems that in the prior art, only a displacement-time sequence can be observed in a real scene, external force information is lost, and fine labeling of a muscle layer is scarce, so that driving mechanical quantity is difficult to recover, evaluation cannot be explained, and engineering landing is difficult are solved.

The utility model discloses a muscular layer and membrane layer separator for human anatomy, which belongs to the technical field of medical instruments and comprises a first knife handle and a second knife handle, the first knife handle and the second knife handle are movably connected through a hinge piece, one end of the first knife handle is integrally connected with a first blade, and the other end of the first knife handle is integrally connected with a second blade. One end of the second knife handle is integrally connected with a second knife edge, the other end of the first knife handle and the other end of the second knife handle are integrally connected with a first handle sleeve and a second handle sleeve respectively, and a protruding part is fixedly connected into the second handle sleeve. Through the combined action of the first handle sleeve, the second handle sleeve and the protruding part, the thumb, the ring finger and the ring finger of a user can be inserted into the two handle sleeves, the pair of unplaning scissors is operated through three fingers, the long-time use stability of the pair of unplaning scissors is improved, through the arrangement of a cushion block and a magnet, the closed state of the pair of unplaning scissors can be kept through the magnetic attraction effect when the pair of unplaning scissors is not used, and the pair of unplaning scissors is convenient to use. The first cutting edge and the second cutting edge are prevented from being automatically unfolded to be damaged.

A method and a system for treating skin tissue are provided. At least one heat generating element is configured to modify temperature of the skin tissue, a muscle stimulating element is configured to provide muscle stimulation to a muscle layer located below the skin tissue, a handheld applicator is configured to be placed in vicinity of the skin tissue to deliver said temperature modification from said at least one heat generating element to the skin tissue and said muscle stimulation from said muscle stimulating element to the muscle layer located below the skin tissue; and a control board configured and operable to activate the at least one heat generating element and the muscle stimulating element according to respective activation patterns; thereby providing one or more treatments to the skin tissue.

The utility model discloses a kind of non-invasive cosmetic injection equipment of multi-channel automatic distribution, including base, it is characterized by: the upper surface of the base is fixedly connected with support block, the upper surface of the support block is fixedly connected with first fixed frame, the fixed connection of the support block has button block, the upper surface of the button block is fixedly connected with threaded rod, the upper surface of the threaded rod is fixedly connected with first gasket.Various injection areas can be adapted, improve the comfort of patient, reduce complication, can ensure that drug is evenly distributed, improve treatment effect, save time, while reducing operation failure and adjustment time in treatment process, the latter can optimize the distribution of drug, so that certain medicament is injected into dermis superficial layer or and injected into muscle layer, ensure the best level distribution of drug, to realize more uniform effect, and improve the individualization and flexibility of treatment, both have stronger practicality.

This invention belongs to the field of food science and engineering technology, specifically relating to a precise stratified anti-aging oral formulation based on a three-phase, five-layer, dual-compartment system, its preparation process, and application. The formulation precisely targets the epidermis, dermis, fat layer, muscle layer, and bone layer, simultaneously addressing aging issues in the skin, muscles, and bones, achieving comprehensive anti-aging. The upper compartment features a dual-color tablet for sustained-release and long-lasting repair, while the lower compartment provides rapid replenishment with an anhydrous formula of small molecules, resulting in high retention of active ingredients and excellent absorption efficiency, balancing "immediate replenishment" and "long-lasting repair." The preparation process parameters for the compressed candy and nutrient beverage have been precisely optimized to ensure product formability and stability, with no significant loss of active ingredients, enabling industrial-scale mass production. Zebrafish experiments and human trials have verified its clear anti-aging efficacy without any adverse reactions, demonstrating high acceptance and satisfaction among test subjects, meeting the safety and efficacy requirements of functional oral foods.

The present invention discloses an intelligent spinal bionic model and relates to the technology of surgical simulation instruments. It includes a model base and a model case, a bionic spinal column body installed on the model base and having a development effect, and a simulated muscle layer and a simulated skin layer enclosing the bionic spinal column body. A bionic nerve body having a contact alarm mechanism is installed in the cavity inside the bionic spinal column body. [Effects] This invention creates a spinal bionic model for surgical simulation through precise design and material selection, faithfully reproducing several important processes in actual spinal surgery (X-ray development, simulation of internal human structure, simulation of the surgical water environment, nerve contact alarm, etc.). It provides physicians with a highly simulated surgical training platform, contributing to the rapid improvement of spinal endoscopic surgical skills and clinical experience.

This invention relates to the field of needle-free injector technology, and in particular to an apparatus and method for needle-free injection of local anesthetics into the dermis for infiltration anesthesia. The apparatus includes a receiving space for containing the anesthetic solution; the injection pressure is 14-21 MPa. This invention allows for the design of different needle-free injectors to address the physiological differences in the dermis between men and women, ensuring precise intradermal injection of the anesthetic solution and avoiding entry into the muscle layer. Furthermore, it results in less pain during injection and a longer duration of effect from the onset and exhaustion of the local anesthetic.

FIELD: medicine.SUBSTANCE: invention relates to simulators for practicing skills of applying surgical sutures to the skin and techniques of tying surgical knots. The simulator includes a multi-layer cushion simulating human tissues, a simulation of vessels in the tissues, and has a rectangular shape with rounded edges measuring 20 by 15 cm and a height of 1.8 cm. The simulator is made of hypoallergenic polymers and contains four layers simulating human tissues - epidermis, dermis, subcutaneous fat, muscles. Vessels of various diameters, filled with a liquid imitating blood, run in the subcutaneous layer. A flap of PVC artificial leather having a skin texture, treated with liquid release wax IZHWAX SP, is placed on a platform with legs measuring 25 by 20 cm. A part in the form of a side 1.75 mm high, printed on a 3D printer, is placed on the flap. A nylon stretch mesh with a density of 110 g / m2 is stretched over the part. The stretch mesh is fixed to the platform with clamps. A part in the form of an outer side with 'ears' 17 mm high, printed on a 3D printer, is installed on the mesh. The entire structure is completely pressed against the base using clamps so that the nylon mesh remains stretched. Platinum silicone rubber of appropriate parameters is poured into a separate container. The components are mixed and coloured with a dye for epoxy resin, and after the last layer hardens, all the existing 3D-printed sides and other parts are separated. The excess stretch mesh is cut off.EFFECT: possibility of performing training of intramuscular injection, layer-by-layer dissection of the simulator layers with a scalpel down to the underlying layers and applying sutures in hard-to-reach places, in particular on the muscle layer, fascia, aponeurosis.1 cl, 1 dwg

A bionic spinal model, including: a base body; an enclosure; a bionic spinal body disposed on the base body and being radiopaque; a simulated muscle layer surrounding the bionic spinal body; and a simulated skin layer overlaying the simulated muscle layer. The bionic spinal body comprises an internal cavity and a bionic nerve body; the bionic nerve body is disposed in the internal cavity; and the bionic nerve body comprises a proximity-sensitive warning mechanism. The model successfully simulates key aspects of real spinal surgery, including X-ray imaging, internal anatomical structures, a surgical fluid environment, and neural proximity feedback, providing a realistic training platform to improve endoscopic spinal surgical skills.

The application discloses a laparoscopic esophagus and jejunum anastomosis training method and belongs to the technical field of laparoscopic operation training. The method is used for operation training of an isolated digestive tract specimen and comprises the following steps: obtaining an isolated esophagus specimen and an isolated jejunum specimen; using a guide support device to press and position a predetermined incision point in the center of the isolated esophagus stump and form an opening by full-layer incision; completing linear stapler anastomosis under the assistance of the guide support device, so that the common opening is located in the central region of the isolated esophagus stump; using the isolated esophagus stump as a positioning mark to close the common opening by full-layer continuous suture; and using the same suture to reinforce each operation suture in the muscle layer. The application solves the problems of poor controllability of a traditional anastomosis training opening, easy mucosal retraction, easy misplacement of an instrument, poor visual field exposure, no suture reference and great difficulty in standardization, can realize accurate positioning, high standardization, and standardized laparoscopic anastomosis training that can be reproduced, and significantly improves the training quality and effect of surgical laparoscopic skills.

The traditional Chinese medicine compound wound styptic powder is prepared from the following components in parts by weight: 15 to 30 parts of radix notoginseng, 10 to 15 parts of rhizoma bletillae, 10 to 15 parts of cuttlebone, 10 to 15 parts of crinis trachycarpi, 10 to 15 parts of carbonized hair, 5 to 10 parts of folium callicarpae pedunculalae, 5 to 10 parts of herba cepbalanoplosis segeti, 5 to 10 parts of pollen typhae and 5 to 15 parts of herba plantaginis. The traditional Chinese medicine has good effects of stopping bleeding, resisting inflammation, astringing wounds and promoting regeneration and repair of wound tissues on small and medium-sized body surface wounds with three-degree-depth wounds (the wounds are 3cm * 3cm, and the depth reaches a muscular layer), and the indexes are obviously superior to those of a control group (Yunnan Baiyao medicine and incised wound medicine).

A cosmetic method for treating a skin of a person is presented, the method comprises inserting one or more needles to one or more depths into the skin of the person such that at least a tip of at least one needle of the one or more needles is deployed within a muscle layer of the person's skin; applying a negative DC voltage to the one or more needles, while a skin of the person is in contact with a positive electrode to form one or more closed circuits of DC current through the person's body; and providing the DC current for a pre-selected amount of time to damage and / or ablate muscles and / or muscle nerve cells in the muscle layer; thereby providing a skin treatment comprising reducing and / or smoothing wrinkles from the person's skin.

The application provides a kind of uterus myoma automatic typing method and device based on deep learning.The method comprises the following steps: constructing semantic segmentation model, input pelvic medical image is divided into mucosa, muscle layer, serosa outside 3 regions;Construct instance segmentation model, segment out uterine fibroids, get uterine fibroids volume V T ;Extract the outline of uterine fibroids, calculate the volume V O Of the uterine fibroids belonging to serosa outside area and the volume V N Belonging to mucosa inside area;Based on V O , V N And V T The uterine fibroids are typed based on FIGO.The whole process of typing uterine fibroids of the application does not need artificial participation, reduces the analysis pressure of imaging department doctors, helps to improve the accuracy and consistency of FIGO typing determination.

The invention provides virtual and real combined teaching equipment for invasive arterial puncture, and relates to the technical field of virtual simulation teaching, and the equipment comprises a puncture simulation module which comprises a skin layer, a muscle layer and a blood vessel layer which are made of a 3D printing silica gel material; the skin disinfection module comprises a capacitive disinfection array and a force sensing array; the VR scene simulation module is used for updating a VR scene, synchronously establishing a module feedback signal and executing real-time training data updating; and the training recording module is used for outputting a training data set. The technical problems that in traditional invasive arterial puncture teaching, virtual simulation and actual operation links are separated, training feedback is not real-time, and teaching data are difficult to quantify can be solved, and the purposes of integrating the VR technology, the 3D printing silica gel material, wireless transmission, data collection and feedback and the like are achieved. And the technical effects of sense of reality, interactivity and accuracy of teaching are improved.

The application discloses a skin temperature prediction method based on a multi-node sleep thermal regulation human body model and belongs to the field of human body thermal comfort prediction. The method comprises the following steps: inputting an environmental temperature, an environmental humidity and a local clothing thermal resistance into a sleep thermal regulation human body model, and calculating a whole body skin temperature by the sleep thermal regulation human body model based on the input data. The sleep thermal regulation human body model divides a human body into six segments, i.e., a head, a trunk, an arm, a hand, a leg and a foot, and each segment comprises four layers from inside to outside, i.e., a core layer, a muscle layer, a fat layer and a skin layer, and each layer is a node, and in addition, a central blood node is further included, so as to form a 25-node sleep human body model. The application can be used for predicting the temperature distribution of each body part of a human body under different indoor environments and clothing conditions when sleeping, the prediction result is close to the actual human body experimental measurement result, time-consuming and high-cost human body experiments are avoided, and the thermal comfort of indoor environment regulation and home textile product use can be judged.

This invention generally relates to the field of medical devices and the establishment of fluid communication between body cavities. In particular, this invention relates to apparatus and methods for placing the muscle layers of first and second body cavities in contact to establish a long-term or permanent open flow or access pathway therebetween.

The invention discloses a mucosa and inherent muscle layer separating and supporting device with a telescopic function, and relates to the technical field of medical instruments.The device comprises an operation assembly and a supporting assembly, the supporting assembly comprises a head sheathing canal, a head block and a supporting column, and the inner wall of the head sheathing canal is slidably connected with the head block; two symmetrical balls are fixedly embedded in the inner wall of the head block, the two supporting columns are connected through a spring and used for supporting the mucosa and the intrinsic muscle layer, one supporting column is provided with a groove corresponding to the balls and connected with the balls in a clamped mode, and the operation assembly is used for operating the supporting assembly to support the mucosa and the intrinsic muscle layer. The supporting assembly can reach the operation view through an operation hole channel of an endoscope, the supporting assembly can be conveniently and flexibly released between an incised mucous membrane layer and an incised intrinsic muscle layer, the mucous membrane layer and the incised intrinsic muscle layer are stably and continuously maintained to be separated, the clear operation view is provided for an operator in the operation process, the operation efficiency is improved, and operation complications are reduced.

The invention relates to the technical field of needleless injectors, in particular to a device and a method for injecting local anesthetic into a corium layer without a needle to infiltrate anesthesia. The device for injecting the local anesthetic into the corium layer without a needle to infiltrate anesthesia comprises a containing space used for containing liquid medicine; wherein the injection pressure intensity ranges from 14 mpa to 21 mpa. Different needleless injectors can be designed according to the physiological difference of male and female corium layers, it is ensured that liquid medicine is accurately injected into the skin and prevented from entering the muscle layer, in addition, during injection, the pain feeling is smaller, and the lasting time effect achieved by the onset time and the failure time of local anesthetics is better.

The utility model relates to the technical field of massagers, and particularly discloses a gynecological traditional Chinese and western medicine combined massager which comprises a massage plate, a storage box is arranged on the surface of the massage plate, a control button is arranged on the surface of the massage plate, and a handle is arranged on the surface of the end, away from the storage box, of the massage plate. The device comprises a first rotating assembly, a kneading assembly and a second rotating assembly, the first rotating assembly comprises a first rotating motor, a first rotating plate, a second rotating plate, a second rotating plate and a second rotating assembly, the moxa fumigation assembly comprises a screen column, a fixed column, a screw rod, a groove block and a moxa stick, and the first rotating assembly comprises a first rotating motor, a movable plate, a pore plate, a driving rod and a second rotating assembly. The second massage head can perform array type muscle massage on the muscles of the patient at a vertical angle, the first massage head can perform kneading massage on the muscles of the patient at a certain amplitude, the manual kneading manipulation is simulated, and the device can go deep into the muscle layer to further relieve muscle tension.