5 results about "Raman microscope" patented technology

The application provides a method and device for measuring lateral spatial resolution of a confocal Raman microscope, and relates to the field of optical measurement and microscopic spectroscopy technology. The method comprises the following steps: positioning a region of a straight edge on a single-layer graphene sample by using a confocal Raman microscope, wherein the single-layer graphene sample is prepared on a silicon oxide substrate; determining a straight scanning path and a scanning step in a direction perpendicular to the straight edge from a bare region of the substrate to a sample region in the region of the straight edge which has been positioned by using the confocal Raman microscope; determining a plurality of scanning points on the straight scanning path based on the scanning step in the process of moving the single-layer graphene sample, and collecting Raman spectrum signals of the scanning points; and measuring the lateral spatial resolution of the confocal Raman microscope based on the Raman spectrum of each scanning point. By using the method provided in the application, the accuracy of the lateral spatial resolution of the confocal Raman microscope can be improved.

This invention discloses a hardware-software co-processing method for real-time spectral signal processing in Raman microscopy, belonging to the field of spectral signal processing technology. The method includes: establishing strict temporal constraints between physical displacement and cloud inference, and initiating asynchronous communication using the physical gaps in stage movement; simultaneously, deploying a deep learning model (F2P) pre-trained with a self-supervised masking strategy in the cloud. This pre-trained model utilizes the structural correlation between the Raman broadband background and narrowband characteristic peaks to directly perform real-time forward inference on the input single-frame noisy spectrum, achieving millisecond-level high-fidelity reconstruction of a single frame without any complex parameter tuning or the need for a clean control spectrum. This invention completely eliminates the physical lag in multi-frame processing and the general technical bias of supervised learning algorithms, achieving true "synchronization between acquisition and display," and significantly improving the real-time processing performance and cross-device automated deployment capabilities of in-situ Raman imaging.

This invention relates to a method for detecting indophenol sulfate based on surface-enhanced Raman spectroscopy. A liquid containing the indophenol sulfate to be detected is mixed with an oxidizing reagent to specifically oxidize the indophenol sulfate to indigo, yielding a mixed solution. This mixed solution is then mixed with gold nanoparticles, and the spectra of the mixed solution are acquired using a confocal Raman microscope. The acquired Raman spectra are baseline-removed to obtain the signal intensity at the target characteristic peak. Based on standard curves for different concentrations of indophenol sulfate and the signal intensity of the sample, the concentration of indophenol sulfate in the test sample is determined. This invention provides clear detection signals, accurate resolution, and a simple operation, enabling rapid and accurate detection of indophenol sulfate concentration in samples (such as serum). It is expected to promote research on the biological mechanisms of indophenol sulfate and its large-scale clinical application.

A battery cell, a battery device, and an electric device. The battery cell comprises a positive electrode sheet, a negative electrode sheet, and an electrolyte; the lithium ion conductivity of the electrolyte is greater than or equal to 10 mS / cm; the negative electrode sheet comprises a negative electrode current collector and a negative electrode film layer disposed on at least one side of the negative electrode current collector; the negative electrode film layer comprises a negative electrode active material; the negative electrode active material comprises a core portion and a coating layer at least partially coating the surface of the core portion; the core portion comprises graphite; and in an R value cumulative distribution curve of the negative electrode active material obtained in a surface scanning mode of a laser confocal Raman microscope / spectrometer, the concentration (R90-R10) / R50 of R values is less than or equal to 2.3.

This invention specifically relates to a method for determining the uniformity of acetylation reaction in modified starch granules. It employs the characteristic peak "intensity ratio method," using a confocal Raman microscope to acquire the Raman spectrum of individual starch granules. The Raman intensity ratio of the characteristic vibrational peak of the ester group (-C=O) to the internal standard peak of the starch skeleton represents the relative magnitude of the modification reaction in a single acetylated modified starch granule. Based on a large number of Raman intensity ratios, a frequency distribution histogram is plotted, and statistical parameters are used to quantify the uniformity of the reaction. Methodological validation results show that this method has good accuracy. This technology solves the technical problem that traditional methods cannot assess the uniformity of acetylation reaction between granules, providing a reliable means for quality control and process optimization of high-quality acetylated starch.