115 results about "Sulfuric ester" patented technology

A thickened oil emulsifying viscosity reducer consists of anion surface activator, non-ionic-anion surface activator, demulsifier and water in proportion by 1:0.1-50:0.01-20 and water content is 0.2-5000 times of the sum of a, b and c. Anion surface activator comprises sodium salt and calcium salt of petroleum sulfoacid salt methyl condensate and sulfonated lignin; non-ionic-anion surface activator is chosen organic phosphate salt, sulfuric ester salt , carboxylate and sulfosalt of alkylphenol or fatty alcohol-polyoxyethylene ether; demulsifier is copolymer of alkyl ammonium halide cation demulsifier, polyethylene glycol polyoxytrimethylene polylol ether non-ionic demulsifier or polyethylene glycol polyoxytrimethylene polyethylene polyamines block. It has strong emulsifying ability and low thickened oil viscosity,

The invention discloses a preparation method of a functional fluorine-containing monomer. The method comprises the following steps of: uniformly mixing a perfluoro-linear chain or branched chain acyl fluoride compound, trifluoroethylene sulfuric ester and anhydrous hydrogen fluoride liquid in the mole ratio of 1:1:(1-20); passing from bottom to top through a vertical-tube type reactor which is filled with a catalyst; finishing addition reaction in a short time under the action of the high specific surface area catalyst inside the reactor; and setting apart a reaction liquid product from the upper part of the vertical-tube type reactor to form a product with a general formula in formula (I). In the invention, the functional fluorine-containing monomer can be prepared continuously and efficiently with easily operated reaction equipment, conveniently controlled reaction temperature and no use of any organic solvent, and a high-purity monomer can be obtained through simple rectification. The catalyst filling in the tubular reactor is one or a mixture of active carbon, macro-porousmolecular sieve and porous aluminum oxide. The reaction can be carried out continuously inside the reactor and satisfies industrialization requirements. CF2=CF-O-Rf(I).

The invention discloses a low molecular weight glycosylated chondroitin sulfate, whose weight average molecular weight is 3000-15000Da. The monosaccharide composition comprises acetyl galactosamine (D-GalNAc), glucuronic acid (D-GlcUA), fucose (L-Fuc), or its sulfuric ester (expressed in -OS03<->), wherein the mole ratio of D-GalNAc to D-GlcUA to L-Fuc to -OS03<-> is 1: (1+/-0.3): (1+/-0.3): (3.5+/-0.5). The low molecular weight glycosylated chondroitin sulfate has a strong anti-HIV-1 virus activity, is a gp120 entry inhibitor, and can be used for preventing and/or treating AIDS. The invention also provides a method for preparing the low molecular weight glycosylated chondroitin sulfate and its composition preparation. Glycosylated chondroitin sulfate is depolymerized by the peroxide method to obtain a low molecular weight product, and then low molecular and/or high-molecular impurities of the product are removed by gel separation or ultrafiltration method. The low molecular weight glycosylated chondroitin sulfate and its medicinal composition can be prepared in the form of an injection, a lyophilized powder or a suppository.

The invention discloses a preparation method of fucoidan sulfuric esterwith high purity and high-sulfate radical content, comprising the following steps: (1) adding water in dry kelp for soaking and rinsing to remove sediment and then grinding; (2) adding the kelp in 95 percent ethanol for stirring, extracting and separating to obtain kelp residue A; (3) adding water in the kelp residue A, adjusting the pH value to 6-8, and stirring, extracting and separating the mixture to obtain kelp residue B and supernatant; (4) adding super calcium chloride in the supernatant, standing and filtering to obtain filtrate; (5) condensing the filtrate to concentrated solution; and (6) directly spraying and drying the condensed solution, or depositing the fucoidan with 40-70 percent ethanol and drying and crushing the dried fucoidan, and finally obtaining the fucoidan sulfuric ester with high purity and high-sulfate radical content, wherein the content of fucose is 40-70 percent and the content of sulfate radical is 30-50 percent. Compared with the prior art, the invention is free from using acid base for treatment and adjusting the pH value, has simple method, less consumption of organic solvent, few steps and low cost, and is suitable for industrial production.

The invention relates to a gemini surfactant containing sulfo group and sulfate group anions, belonging to the field of design of oilfield chemical agents. The gemini surfactant is characterized by having the structural formula shown in the specification, wherein n is 8, 10, 12, 14 and 16. A preparation method of the gemini surfactant provided by the invention comprises the following steps: (1) open-loop esterification reaction between maleic anhydride and fatty alcohol; (2) double-bond oxidation reaction of maleate diether; (3) substitution reaction of epoxy succinate diether; (4) esterification reaction of succinate diether sodium sulfonate. The gemini surfactant containing sulfo group and sulfate group anions, provided by the invention, contains the anion structures of sulfate group and sulfo group, has relatively high surface activity and strong foaming ability, and has the characteristics of simple synthesis method, mild reaction conditions, simplicity in operation, easiness in separation and high yield.

The present invention relates to process of synthesizing water absorbing polymer resin, and is especially process of synthesizing water absorbing nanometer dispersive CMC-acrylate polymer resin. The process includes the following steps: 1. preparing materials including acrylic acid 10-50 weight portions, sodium hydroxide 3-10 weight portions, water 8-20 weight portions, CMC 1-10 weight portions, N, N'-methylene biacrylamide 0.01-0.5 weight portion, ammonium persulfate 0.01-1 weight portion, normal hexane 20-200 weight portions and sulfuric ester type surfactant 10-100 weight portions; 2. reacting the materials in a reaction kettle with introduced nitrogen while stirring and heating to 60-70 deg.c for 4-6 hr; 3. cooling through leading water to the jacket of the reaction kettle, and discharging the resultant; and 4. drying to obtain the product. The water absorbing polymer resin may be dispersed homogeneously in water solution.

The invention discloses orange active dye and a preparation process, which uses 2, 4-di-sodium sulfanilate as coupling component, uses 2-naphthylamine-disulfonic acid and beta-carboxy ethyl sulfuryl sulfuric ester aniline as diazo component, and is prepared through two-time coupling, filtering, drying and packaging. The active orange dye has extremely excellent dissolving property, over 96% dyeing exhausting rate, is significantly superior to acid dye, and greatly reduces the difficulties to treating environment.

The invention discloses a method for preparing 3-O-alkyl ascorbic acid. The method comprises an etherification reaction step and a separation and purification step, wherein in the etherification reaction step, in a nitrogen atmosphere, vitamin C, alkali and an alkylating agent are mixed and dissolved in a solvent A to be reacted, and the reactants are reacted for 1 to 5 hours at room temperature and in a refluxing state to form solution of 3-O-alkyl ascorbic acid. The alkylating agent is one or more of toluene sulfonic acid, sulfuric ester and carbonate; the solvent A is one or more of methanol, ethanol, isopropyl alcohol, tetrahydrofuran and acetone; a molar ratio of the vitamin C to the alkali to the alkylating agent is 1:1-2:1-2; and a weight ratio of the solvent A to the vitamin C is 2-4:1. The preparation method has the advantages of simple method and low cost. The obtained 3-O-alkyl ascorbic acid is high in yield and purity.

The present invention discloses one kind of new compound sodium alginate sulfate and its preparation. The preparation process includes adding ad alginate into sulfatizing reagent, reaction at 40-70 deg.c to obtain reddish brown solution, dialysis and concentration to obtain sodium alginate sulfate. The in vitro blood coagulation with the obtained sodium alginate sulfate shows that it has very high anticoagulant activity and has APTT value reaching the level of haparin in the said concentration, so that sodium alginate sulfate may be used as anticoagulant in preparing blood coagulation resisting medicine.

An anti-tumour activated Tuckahoe sclerotium glucan sulfuric is prepared by: taking fresh Tuckahoe sclerotium, extracting non-water soluble (1->3)-beta- D- glucan with NaOH, solving them in anhydrous dimethylsulfoxide, adding pyridine and chloro-sulfonic acid to react to get glucan sulfuric ester. The glucan sulfuric ester's substituted reaction is of non-selective substitution, occurred at C-6 position of hydroxy, the substitution value of sulfuric ester is 0.66- 1.21, weight-average molecular weight is 0.8X104-16.4X104, and has well water solubility. Testing in vivo and in vitro showed that, the glucan sulfuric ester has obvious inhibit effect for Sarcoma 180 and proliferation of adenocarcinoma of stomach. The toxic testing in small rat prove that half lethal dose of glucan sulfuric ester (LD50)>1600 mg/kg, and without toxic or side effects. The Tuckahoe sclerotium glucan sulfuric ester is capable of use in preparing anti-tumour pharmaceuticals or health food with function of increasing body immunological competence.

Disclosed are an agent for suppressing transfer of odor and taste originating from a diacetal such as dibenzylidene sorbitol, comprising (B) an aliphatic alcohol or an aliphatic carboxylic acid containing at least one hydroxyl group, or comprising component (B) and (C) at least one member selected from the group consisting of specific sulfuric ester salts, saturated or unsaturated fatty acid alkali metal salts and aliphatic amines; a diacetal composition comprising the suppressing agent and the diacetal; a resin composition and a molded product comprising the diacetal composition and a polyolefin resin; and a method for suppressing transfer of odor and taste originating from the diacetal, or a method for suppressing aldehyde generation by thermal decomposition of the diacetal, comprising using the suppressing agent.

The invention discloses an alga polysaccharides sulfuric acid ester composition and an application of the composition in regulating immunity. The composition contains alga polysaccharides sulfuric acid ester, bee glue or flavonoids extractives as active regulating ingredients. Tests show that the composition can be applied to drugs or health products which can adjust the balance of human immune system after long-term usage; simultaneously, the composition can enhance the ability of human bodies on fight diseases, and strengthen the human body anti-fatigue capability. The invention also discloses the preparation technique of the composition.

The invention discloses orange reactive dye and the preparation method thereof. The dye and the structural formula thereof are as follows: the preparation method comprises the following steps: after the unipolycondensation reaction of tricyanogen chloride and cyanamid, the copolycondensation reaction is performed with J acid; Beta sulfuric ester ethyl sulfone amino benzene is diazotized to obtain diazo salt, and then the diazo salt is added into copolycondensation compound to perform the coupling reaction, to obtain mono azo dye; 2amido ethyl-2(1) sulfonyl ethoxyl sulphone is added into mono azo dye solution to perform the tri-polycondensation reaction. The invention has the advantages of high color fixation rate, good building up property and level dyeing property, good sun-proof performance, sweat resistance and washing fastness, which is suitable for the cellulose fiber dying and simultaneously suitable for the fiber dying such as direct viscose and artificial amiray ramie, etc.

The invention discloses a compound which contains fucoidan and ginseng. The invention discloses the application of the compound in drugs and health care products for preventing chemical liver injury and regulating immunity. The research of the inventor shows that the drugs or the health care products applying the compound have good effect on regulating the balance of the body immune system, enhancing the capability of resisting against diseases and treating chemical liver injury by being taken for a long term. The invention also discloses a preparation technique for the compound.

Provided are an imidazoline quaternary ammonium salt compound and a preparation method therefor. Lauric acid and hydroxyethyl ethylenediamine are employed as raw materials, a dehydration reaction is carried out, imidazoline intermediates are synthesized, and then after quaternization, an imidazoline quaternary ammonium salt compound is obtained, wherein a quaternized reagent is sulfamic acid. Sulfamic acid is employed as a quaternized reagent, thus the quaternization reaction is carried out easily, and the product water solubility is raised. The imidazoline quaternary ammonium salt employs sulfamic acid as a quaternized reagent, and sulfamic acid has low toxicity, and is cheap and easily available. An imidazoline sulfuric ester salt is obtained through the method, and the imidazoline sulfuric ester salt is an amphoteric substance. The product contains -SO3 hydrophilic groups, the water solubility is good, the inhibition efficiency is high, water solubility requirements of imidazoline products can be met, and popularization in the industrial process is worthy. The synthetic technology is simple, the production processes are environmentally friendly, and the purposes of lowering the corrosion inhibitor cost and raising the operation safety are achieved.

The present invention discloses carboxyl butyryl chitosan sulfate. It is prepared through dissolving chitosan sulfate with sulfur content of 3-20 wt% and molecular weight of 5000-20000 in distilled water to obtain 5-30 wt% concentration chitosan sulfate aqua in homogeneous phase condition; adding succinic anhydride, mixing and reaction through stirring at 20-30 deg.c; dialysis and freeze drying to obtain carboxyl butyryl chitosan sulfate. The present invention has the advantages of mild reaction condition, easily controlled carboxyl substituting degree, less side reaction, high selectivity, etc. The carboxyl butyryl chitosan sulfate of the present invention has very high anticoagulant activity and may be used in preparing blood coagulation resisting medicine.

This invention relates to a new chitosan sulfate metal complex and perparing method thereof. In the formula 1, M=Cu or Zn, n is 56-6211, m/n is (1/36)-(1/2), R1 is H or Ar, R2 is H or Na. First, chitosans in different molecular weight react with metal complex, then react with sulation reagent under micro-wave rediation to prepare the chitosan sulfate metal complexes in different molecular weight. Said method also can be used to the sulfation reaction of other polysaccharides. Advantages: low toxity and easy for absorbing, good water solubility, good synergetic effect becouse of the good joint of metal ions, sulfate group and chitosan molecular, obviousely enhanced biological activity of chitosan itself.

The invention relates to a carrageenin in-situ forming gel spray for noses, and a preparation method of the carrageenin in-situ forming gel spray for noses, and belongs to the technical field of medicine and pharmacy. The gel spray comprises the following components in percentage by weight: 5-7% of kappa type carrageenin, 3-5% of iot type carrageenin, 0.001-0.005% of lambda type carrageenin, 5-16%of acceptable auxiliary materials in an external preparation for skin, and the balance water. Firstly, through regulating the consumption ratio of the kappa type carrageenin to the iot type carrageenin, the proportion of sulfuric ester content in a mixture is changed, when the gel spray is sprayed into the noses, the elasticity of gel can be improved through potassium ions and calcium ions in nasal cavity secretions, and besides, synaeresis of the gel can also be prevented. An inflammatory reaction is activated through an appropriate amount of the lambda type carrageenin, and human body localimmunization capacity substances are activated to form a layer of film on the surface of a nasal cavity, so that a virus infection way is blocked, and infection of respiration diseases is prevented.The gel spray is simple in preparation method, easy to operate, low in equipment requirements and suitable for large-scale production.

Disclosed are a granular or powdery diacetal composition comprising (A) a diacetal such as 1,3:2,4-O-dibenzylidene-D-sorbitol, (B) a sulfuric ester salt and (C) an aliphatic monocarboxylic acid, components (B) and (C) being uniformly dispersed in the particles of the granular or powdery diacetal composition, and component (B) being present in a proportion of 0.1 to 3 wt % and component (C) being present in a proportion of 0.3 to 5 wt %, and the total amount of component (B) and component (C) being not more than 7 wt %, based on the diacetal composition; a polyolefin resin composition comprising the diacetal composition and a polyolefin resin; a process for preparing the resin composition; and a molding prepared by molding the polyolefin resin composition.

The present invention discloses one kind of oligoglucose sulfate and its preparation process. The oligoglucose sulfate with relatively great molecular weight is obtained through simultaneous esterification and decomposition in organic solvent dispersed concentrated sulfuric acid, and may be further hydrolyzed or enzymolyzed to reduce its molecular weight. The oligoglucose sulfate prepared with cellulose and starch as material has controllable structure, and adjustable molecular weight and sulfate radical substitution degree. It possesses immune regulating effect and anticancer activity, simple preparation process and rich material source.

The invention discloses a lipase determination kit and a preparation method thereof. An R1 reagent comprises a buffer solution, sodium deoxycholate, colipase, metal salt, a protective agent, a surfactant and a preservative; an R2 reagent comprises Ltartaric acid, calculus bovis deoxycholic acid sodium salt, 1, 2-o-dilauroyl racemic glycerol 3valeric acid (6methyl resorufin) ester, a cosolvent, a stabilizer and a preservative, and the cosolvent is composed of ethyl acetate, dilauroyl glycerol sulfate and a Triton surfactant. According to the invention, through optimization, ethyl acetate, dilauryl glyceryl sulfate and Triton surfactant are jointly used as a cosolvent to play a synergistic effect of the three components, so that the solubility of a substrate is greatly improved, and further,mercaptoethanol and mannitol are used as composite stabilizers, therefore, the lipase determination kit which is good in stability, high in accuracy and precision and remarkably improved in linear range is obtained.

A cleaning solution of the present invention contains a sodium ion, a potassium ion, an iron ion, an ammonium salt of a sulfuric ester represented by General Formula (1), and water, and each content of the sodium ion, the potassium ion, and the iron ion is 1 ppb to 500 ppb. ROSO₃—(X)+ (1) where R is an alkyl group with a carbon number of 8-22 or an alkenyl group with a carbon number of 8-22, and (X)+ is an ammonium ion.

The invention discloses o-methoxy-beta-sulfuric ester ethyl sulfonyl aniline and a preparation method thereof. The o-methoxy-beta-sulfuric ester ethyl sulfonyl aniline is used as a raw material for synthesizing dyes such as reactive blue 250, and the like, and is prepared according to the following steps: o-aminoanisole is acetylized by using acetic anhydride solution; the obtained acetylized compound is sulfonated by using chlorosulfuric acid and thionyl chloride; the obtained sulfonate is reduced by using sodium bisulfite and sodium hydroxide; the reducing substances are condensed by using ethylene oxide; and the obtained condensation compound is esterified by using sulphuric acid to obtain the product. The reactions are realized by mixing, dissolution and stirring in a reaction container and adopting the methods of vacuum heating, slicing, diluting, clarification, washing, suction filtering, drying and crushing. The invention solves the problems that the prior product depends on import and has high use cost and complex process, and has the advantages of simple manufacture method, easy operation and high effective content up to more than 97 percent.

The invention relates to a method for chemical modifying of ginsenoside and separating identification of a ginsenoside derivative, in particular to a method for sulfation modifying of 20(S)-ginsenoside Rh2 and a method for separating identification of 20(S)-ginsenoside Rh2 sodium sulfovinate generated from 20(S)-ginsenoside Rh2. The invention is characterized in that the prepared chlorosulfonic acid-pyridine esterifying agent is reacted with 20(S)-ginsenoside Rh2; and by the column chromatography separation technique, two target compounds of the 20(S)-ginsenoside Rh2 sodium sulfovinate are obtained. The spectroscopy proves that except keeping infrared spectrum characteristic peak, the number of sulfuric ester bonds of the target compositions is increased, the molecular weights are both 724, H of -OH of a Rh2 molecular replaces a -SO3Na group, and the two target compounds are a pair of isomers. The aim of the invention is to provide a sulfation modifying method for reconstructing molecular structure of the ginsenoside, provide scientific base and new research thought for finding ginsenoside derivatives with stronger biological activity, and provide though for deeply developing ginsenoside compound.