44 results about "Isobutylamine" patented technology

The invention discloses an LC-MS / MS positive ion mode detection method of EDTA in food (particularly wine). The method comprises the steps that 1, a sample to be detected is pretreated, wherein 11, the sample to be detected is sucked into a container capable of being closed, a 20.0 mg / L boric acid solution and a 10% amine methanol solution (preferentially, a 10% butyl amine methanol solution) are added, and the container is closed for even mixing; 12, the solution obtained through the step 11 passes through a microporous filtering film with the pore diameter being 0.1-0.5 micrometer to obtain a filtrate; 2, the filtrate is placed into a sample bottle, then, an amine methanol solution is added, sufficient and even shaking is carried out, and then detection is carried out through liquid chromatogram and tandem mass spectrum. The method can qualitatively and quantitatively analyze and detect EDTA in food such as wine, and is good in stability, accurate and sensitive, the qualitative limit is 0.0001 mg / kg, and the quantitative limit is 0.001 mg / kg; the detection method is simple, method errors are avoided, consumed time is short, energy consumption is low, and the application and popularization prospect is good.

The invention relates to a method of obtaining and purifying 2-(2-nitrovinyl)furane consisting in reacting furfural and nitromethane, using isobutylamine as a catalyst and activated carbon as an adsorbent, in order to obtain a product of pharmaceutical quality. Said technique considerably reduces the environmental impact by eliminating the gaseous waste from the system by means of absorption in water. The inventive pharmaceutical composition contains 2-(2-nitrovinyl)furan and has powerful action against low concentrations of coccidia.

The invention discloses recombinant escherichia coli for producing isobutylamine as well as a construction method and an application of the recombinant escherichia coli. According to the present invention, the Escherichia coli Sval031 is adopted as the starting strain, the gene of the L-valine decarboxylase derived from Streptomyces viridifaeces is integrated to the starting strain, the expression intensity of the valine decarboxylase is improved by using the M1-93 promoter through the gene expression intensity regulation and control on the chromosome so as to obtain the isobutylamine high-yield strain ISO-001, the isobutylamine yield can achieve 52.7 g / L, and the conversion rate can reach 0.92 mol / mol. In order to further improve the production efficiency of the isobutylamine, the inventor of the invention optimizes the expression intensity of the VlmD gene by using an RBS library regulation technology, the strain ISO-I with higher production efficiency of the isobutylamine is obtained, and the yield of the isobutylamine is further improved by 66.4 g / L. The method realizes industrial fermentation production of isobutylamine, and has very strong industrial application potential.

The present invention provides an optically active compound of general formula (I) and salts thereof: wherein R′ is selected from a group consisting of t-butyl amine, n-butylamine, iso-butylamine, iso-propyl amine, 4-phenyl-piperazine-1-ylamine, 4-(2-methoxyphenyl)-piperazin-1-ylamine, and 3,4-dimethoxy phenethyl amine; wherein R1, R2 and R3 are selected from the group consisting of hydrogen, methyl or iso pentenyl; R4, R5 and R6 are selected from the group consisting of Oil, O-alkyl, O-benzyl, O-substituted phenyl or combination thereof.

The invention discloses a blue light perovskite light emitting diode and a preparation method thereof. The blue light perovskite light emitting diode of the present invention comprises a blue light perovskite light emitting layer, and the composition of the blue light perovskite light emitting layer includes CsBr, PbBr 2 , isobutylamine hydrobromide and 1-phenyl biguanide hydrochloride. The preparation method of the blue light perovskite light-emitting diode of the present invention includes the following steps: 1) coating the PEDOT:PSS solution on the anode layer to form a hole transport layer; 2) adding CsBr, PbBr 2 , the solution of isobutylamine hydrobromide and 1-phenyl biguanide hydrochloride is coated on the hole transport layer to form a blue light perovskite light-emitting layer; 3) the electron transport layer and the cathode layer are successively evaporated on the blue light On the perovskite light-emitting layer, a blue-light perovskite light-emitting diode is obtained. The blue light perovskite light emitting diode of the present invention can realize blue light emission, has high external quantum efficiency, simple preparation method and low production cost.

The invention relates to the technical field of biomedicine, and particularly discloses a peptoid targeting Abeta42 fibrosome as well as a preparation method and application thereof. The peptoid comprises a first subunit: cysteine, a second subunit: 1,4-butanediamine, a third subunit: isobutylamine, a fourth subunit: ethanolamine, a fifth subunit: furfuryl amine, a sixth subunit: isobutylamine and a seventh subunit: 1, 4-butanediamine. The peptoid provided by the invention can be combined with a surface plasmon resonance imaging technology to detect Alzheimer's disease or amnesia mild cognitive impairment, and has the advantages of high specificity and strong sensitivity. In addition, the content of Abeta42 fibrosome in blood can be noninvasively and directly detected, the AD patients and normal people can be effectively distinguished by identifying AD marker amyloid protein in serum, and a new liquid biopsy method and thought are provided for diagnosing and monitoring the progress of the Alzheimer's disease or the amnesia mild cognitive impairment and medicine research and development.

The invention discloses a strain of recombinant Escherichia coli producing isobutylamine, its construction method and application. The inventors of the present invention used Escherichia coli Sval031 as the starting bacterium, integrated the gene encoding L-valine decarboxylase derived from Streptomyces viridifaciens into the starting bacterium, and used M1 by regulating the intensity of gene expression on the chromosome The ‑93 promoter increased the expression intensity of valine decarboxylase, and obtained the isobutylamine high-yielding strain ISO‑001. The isobutylamine production can reach 52.7g / L, and the conversion rate can reach 0.92mol / mol. In order to further improve the production efficiency of isobutylamine, the inventors of the present invention have optimized the expression intensity of the VlmD gene by using the RBS library control technology, and obtained the strain ISO-I with higher production efficiency of isobutylamine, and the output of isobutylamine has further improved. The increase of 66.4g / L. The invention realizes the industrial fermentation production of isobutylamine, and has very strong industrial application potential.

The invention relates to a ZSM-22 / ZSM-23 composite molecular sieve and a method for synthesis it, which contains: mixing ZSM-22 molecular sieve with alumina silica colloid prepared by mixing carbon source, aluminum source, inorganic base, water with template agent, and adjusting the acid-base quality of the solution with inorganic acid to prepare initial colloid, the mole composition of the colloid being: SiO2 / Al2O3= 60-300, R / SiO2= 0.05-3, OH- / SiO2= 0.05-0.5, M / SiO2=0.1-0.5, H2O / SiO2= 10-65, the usage of ZSM-22 molecular sieve being 1-60% of silica dioxide by weight, and the temperatureagent being one or more of pyrrolidine, isopropyl amine or isobutylamine. The ZSM-22 / ZSM-23 composite molecular sieve is prepared by hydrothermal crystallization of initial colloid.

The invention relates to the technical field of biomedicine, in particular to peptoid. The invention in particular relates to the peptoid as well as a preparation method and application thereof. The peptoid is prepared from ethylenediamine, 4-phenylbenzylamine, beta-phenylethylamine, tetramethylene diamine, 3,4-methylenedioxy benzylamine, isobutylamine, R(+)-alpha-methylbenzylamine, glycine and 3-aminopropionic acid subunit. The peptoid provided by the invention has high sensitivity for beta-amyloid protein in serum, and can be used for effectively distinguishing the serum of a patient and the serum of a normal person by identifying the beta-amyloid protein in the serum, thus providing a new choice for diagnosis and monitoring of Alzheimer's disease.

The invention provides poly-silicon resin as well as a preparation method and application thereof, and relates to the technical field of building sealing. The poly-silicon resin is prepared from the following raw materials in parts by weight: 200 to 220 parts of poly-silicon resin intermediate products, 130 to 150 parts of dihydroxy polydimethyl silane, 190 to 200 parts of methyltrimethoxysilane,21 to 24 parts of methanoic acid and 60 to 65 parts of isobutylamine, wherein the poly-silicon resin intermediate products are prepared from the following raw materials in parts by weight: 210 to 230parts of methyl-triisopropoxy-silane, 140 to 160 parts of toluene and 100 to 110 parts of inorganic acid solution. The silicone sealant coating solution is prepared from the following raw materials inparts by weight: 15 to 25 parts of polysilane rubber, 7.5 to 15 parts of methyl trimethoxy silane hydrolysate, 5 to 10 parts of silane coupling agents and 0.05 to 0.2 part of tin catalysts. The silicone sealant coating solution is applicable to concrete joint seams, and has excellent adaptability. After the treatment by the bottom coating solution provided by the invention, the bonding performance of the silicone sealant on concrete substrates can be obviously improved; the bonding performance of the silicone sealant after the water soaking can also be obviously improved.

The invention relates to a ZSM-22 / ZSM-23 composite molecular sieve and a synthesis method thereof. The silica-alumina colloid obtained by mixing silicon source, aluminum source, inorganic alkali, water and template is mixed with ZSM-22 molecular sieve. The molar composition of silica-alumina colloid is: SiO2 / Al2O3=60~300, R / SiO2=0.05~3, OH- / SiO2=0.05~0.5, H2O / SiO2=10~65, the amount of ZSM-22 molecular sieve added is 0.01~0.6 of the weight of silica, and the template agent is one of pyrrolidine, isopropylamine and isobutylamine or several. The obtained reaction mixture is hydrothermally crystallized to obtain a composite molecular sieve. The composite molecular sieve of the invention exhibits excellent catalytic performance when used in the isomerization dewaxing process of lubricating oil.

Aqueous acidic copper electroplating bath comprising: copper ions; at least one acid; halide ions; at least one sulfur containing compound selected form the group consisting of sodium 3-mercaptopropylsulfonate, bis(sodiumsulfopropyl)disulfide, 3-(N,N-dimethylthiocarbamoyl)-thiopropanesulfonic acid or the respective sodium salt thereof and mixtures of the aforementioned; at least one amine reaction product of diethylamine with epichlorohydrin or an amine reaction product of isobutyl amine with epichlorohydrin or mixtures of these reaction products; at least one ethylene diamine compound selected from the group having attached EO-PO-block polymers, attached EO-PO-block polymers and sulfosuccinate groups and mixtures thereof; at least one aromatic reaction product of benzylchloride with at least one polyalkylenimine and a method for electrolytically depositing of a copper coating using the electroplating bath.