The invention relates to an applicator, in particular to a hand-pressing type applicator. The hand-pressing type applicator aims at achieving the technical purposes that the smearing area is larger, liquid medicine is more uniformly smeared, and air can be filtered. According to the technical scheme, the hand-pressing type applicator comprises a handle rod, a piston, a push rod, a first spring, apressing plate, a first valve, an air suction pipe, a second valve, a medicine bottle, a bottle cap, a second spring, a sprue, a medicine smearing shell and the like. A first cavity and a through holeare formed in the handle rod, the first cavity is located in the right side of the through hole, the first cavity is communicated with the through hole, the piston is slidingly arranged in the firstcavity, the push rod is arranged in the middle of the right side of the piston, the pressing plate is arranged at the right end of the push rod, and the left side of the pressing plate is connected with the first spring. Compared with a cotton swab, the smearing area of a medical sponge is larger, the smearing frequency of people is reduced, repeated smearing is not needed, the workload of smearing staff is relieved, and smearing of people is facilitated.