The invention relates to a novel unmanned aerial vehicle for pesticide spraying. The novel unmanned aerial vehicle comprises a vehicle body, rotor wings, a pesticide tank and a taking-off and landingsupport, wherein a limiting frame is arranged at the middle position of the lower end of the vehicle body, the pesticide tank is placed on the limiting frame, the limiting frame comprises a fixing plate, a rotary supporting plate, a fastening block and a fastening screw, the lower end of the fixing plate is connected with the rotary supporting plate through a rotary shaft, a sliding block is fixedly arranged at the lower end of the fastening block, a connecting screw hole if formed in the upper end, the upper end is in threaded connection with the fastening screw through the connecting screw hole, the fastening screw and the fastening block are in vertical shapes, the outer end of the fastening screw is sleeved with a fastening piece, a sliding groove matched with the sliding block structure is formed in the inner surface of the rotary supporting plate, and a limiting screw hole matched with the fastening screw structure is formed in the upper end of the fixing plate. The pesticide tank is cuboid, and spraying devices are arranged on two sides of the lower end face of the pesticide tank. The taking-off and landing support comprises a connecting rod and supporting rods, wherein thesupporting rods and the vehicle body are kept in parallel. The novel unmanned aerial vehicle has the advantages of being convenient to use, capable of saving energy, efficient and wide in applicationrange.