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Treating pain by administering 24 hours opioid formulations exhibiting rapid rise of drug level

InactiveUS20020058050A1Great analgesic efficacyQuick releaseOrganic active ingredientsCosmetic preparationsAbsorption Half-LifeOral medication
Patients are treated with 24-hour oral sustained release opioid formulations which, upon administration, provide an initially rapid opioid absorption such that the minimum effective analgesic concentration of the opioid is more quickly achieved. These sustained release opioid formulations include an effective amount of at least one retardant material to cause said opioid analgesic to be released at a such a rate as to provide an analgesic effect after oral administration to a human patient for at least about 24 hours, and are characterized by providing an absorption half-life from 1 to about 8 hours. A method of titrating a human patient utilizing these sustained release opioid formulations is also disclosed.
Owner:PURDUE PHARMA LP

Method of treating pain by administering 24 hour oral opioid formulations exhibiting rapid rate of initial rise of plasma drug level

Patients are treated with 24-hour oral sustained release opioid formulations which, upon administration, provide an initially rapid opioid absorption such that the minimum effective analgesic concentration of the opioid is more quickly achieved. These sustained release opioid formulations include an effective amount of at least one retardant material to cause said opioid analgesic to be released at a such a rate as to provide an analgesic effect after oral administration to a human patient for at least about 24 hours, and are characterized by providing an absorption half-life from 1 to about 8 hours. A method of titrating a human patient utilizing these sustained release opioid formulations is also disclosed.
Owner:SACKLER RICHARD S +2

Method And Apparatus For Detecting Faces In Digital Images

A method of detecting faces in a digital image comprises selecting a sub-window of the digital image. Sample regions of the sub-window are then selected. The sample regions are analyzed to determine if the sub-window likely represents a face.
Owner:SEIKO EPSON CORP

Vehicle control apparatus, vehicle control method, and storage medium

A vehicle control apparatus includes a recognizer which recognize a surrounding situation of a host vehicle, and a driving controller which controls acceleration / deceleration of the host vehicle on the basis of a recognition result of the recognizer, wherein the driving controller causes the host vehicle to operate in any of a first driving state and a second driving state which has a higher rate of automation or fewer tasks requested with respect to an occupant than the first driving state, and changes a driving state of the host vehicle to the second driving state on the basis of at least one of presence or absence of a recognized following vehicle positioned behind the host vehicle and a following vehicle detection situation when the host vehicle is operating in the first driving state.
Owner:HONDA MOTOR CO LTD

Mismatch error calibration method for multi-channel high-speed parallel alternate sampling system

The invention provides a mismatch error calibration method for a multi-channel high-speed parallel alternate sampling system, which is characterized by comprising an offset and gain mismatch error calibration step and a time mismatch error calibration step, wherein the time mismatch error calibration step comprises the estimation of time mismatch error and the calibration based on the estimation of time mismatch error. The mismatch error calibration method for a multi-channel high-speed parallel alternate sampling system can estimate and calibrate three kinds of mismatch errors online and in real time, and is a self-adaption calibration method for blind signals. When the external environment is changed, a filter coefficient is not required to be regulated, a calibration module is further not required to be designed again, and the three kinds of mismatch errors can be estimated and calibrated online and in real time. Compared with the prior art, the mismatch error calibration method for a multi-channel high-speed parallel alternate sampling system has lower complexity and can calibrate and output effective data in real time.
Owner:UNIV OF ELECTRONICS SCI & TECH OF CHINA

Ducted fan flexible aerial ladder fire truck

ActiveCN101574565AGuaranteed long-term continuityHigh speedFire rescueFlight vehicleDrive shaft
The invention relates to a ducted fan flexible aerial ladder fire truck comprising an aerocraft consisting of a work cabin and four ducts. Fans are arranged in the ducts. Each duct is connected with a group of driving devices. Each driving device consists of a power mechanism and a deflection mechanism, wherein the power mechanism consists of an engine and a transmission shaft, and the deflection mechanism consists of a large bearing seat, a driving gear, a driven gear and a servo motor. A lateral surface of each duct is fixedly connected with a cantilever supported by a large bearing in the large bearing seat. The engines are fixed on brackets. The transmission shafts pass through the inside of the cantilevers. The front ends of the transmission shafts extend into the ducts and connected with fan shafts by bevel gear drive pairs. The rear ends of the transmission shafts are connected with output shafts of the engines by couplings. The driven gears are fixed connected on the cantilevers. The driving gears are fixedly connected on the spindles of the servo motors and engaged with the driven gears. A high-pressure water gun is arranged at the center inside the work cabin. The fire truck is conveniently used, can extinguish fire and rescue persons and is not limited of the height of a building.
Owner:北京大业嘉成科技有限公司 +2

Rapid identification of bacteria from positive blood cultures

InactiveUS20050037408A1Reduce unnecessary useAvoid developmentMicrobiological testing/measurementBiological testingRapid identificationPositive blood culture
Disclosed is a method of detecting bacteria in a biological sample, especially a blood sample, without the need for extensive sub-culturing of the sample. Nucleic acid present within the sample is isolated and bacterial DNA specifically amplified using primers that uniquely prime the amplification of 16s rRNA-encoding nucleic acid. The amplicons are then digested with an endonuclease to yield a restriction fragment length profile for the biological sample. The restriction fragment length profile for the biological sample is then compare to a database of profiles made using cultures of known bacterial species. A match between the sample profile and the database quickly identifies the bacteria present in the sample.
Owner:MARSHFIELD CLINIC

Amplifier circuit for capacitive transducers

An amplifier circuit for capacitive transducers, such as miniature electret or condenser microphones, wherein the amplifier circuit comprises bias control means adapted to improve settling of the amplifier circuit. Another aspect of the invention relates to a miniature condenser microphone and a monolithic integrated circuit comprising an amplifier circuit according to the present invention. The present invention provides amplifier circuits of improved performance by resolving traditionally conflicting requirements of maintaining a large input resistance of the amplifier circuit to optimize its noise performance and provide fast settling of the amplifier circuit.
Owner:TDK CORPARATION

Reflection space image based rendering

The present invention provides a method, system, and computer program product for reflection space image based rendering of an object at an interactive frame rate. A set of source radiance environment maps associated with a set of source viewing vectors are warped to create a destination radiance environment map associated with a destination viewing vector in a current frame. Blending and weighting operations can also be applied in creating the final destination radiance environment map. An object is then rendered with texture environment mapped from the destination radiance environment map.
Owner:MICROSOFT TECH LICENSING LLC

Non-sine time-domain quadrature modulation method

The invention provides a non-sinusoidal time domain orthogonal modulation method which is non-sinusoidal wave modulation based on orthogonal pulse transmission information. Signals to be transmitted are modulated onto a time domain orthogonal impulse group and impulse parameters are regulated to realize the spectrum shifting and the spectrum control of the modulated signals. The modulated signals are band-limited signals, the spectrum characteristic of which can be controlled. The modulated signals can be applied to any communication frequency band. Communication with relative large bandwidth or broadband communication can be realized, and communication with relative small bandwidth or narrowband communication can be realized. In spectrum management, the method can be compatible with an existing frequency band-division and channel-division communication mode of a relative small bandwidth communication system. And the frequency band utilization rate of the system can infinitely approach Nyquist rate with the increase of orthogonal impulses.
Owner:中国人民解放军海军航空大学航空作战勤务学院

Design method for Variable parameter neural solver for motion planning of redundancy mechanical arm

The invention discloses a design method for a variable parameter neural solver for motion planning of a redundancy mechanical arm. The method comprises the following steps that the solved task is converted into a performance index and a constraint condition of the redundancy mechanical arm; the performance index and the constraint condition is converted into a time-varying quadratic programming standard form of a to-be-solved system; according to a lagrangian multiplier method, the optimal value in the time-varying quadratic programming standard form is optimized; optimized information is converted into a standard time-varying matrix equation form; a deviation function is designed according to the standard time-varying matrix equation form; according to the deviation function and a power type variable parameter recursion neural dynamics method, the variable parameter neural solver used for the motion planning of the redundancy mechanical arm on a real number field is designed; and a network state solution obtained through the variable parameter neural solver is the optimal solution for the motion planning of the redundancy mechanical arm system. The method has the advantages of being high in calculation speed, high in precision, fast in convergence, high in instantaneity, and good in robustness.
Owner:SOUTH CHINA UNIV OF TECH

Anti-noise-interference redundant manipulator path planning method

The invention discloses an anti-noise-interference redundant manipulator path planning method and a system. The method comprises the steps of (1) building a time-varying quadratic planning model according to an actual redundant manipulator parameter index, and introducing a performance index of a redundant manipulator; (2) using a lagrange multiplier method for carrying out optimal value optimization on the time-varying quadratic planning model; (3) designing a standard matrix equality according to an optimization formula; (4) designing a deviation function equation of the system according toan actual physical model system and the standard matrix equality; and (5) designing the anti-noise-interference redundant manipulator path planning method according to the deviation function equationand a power type varying parameter recursion neurodynamics method, wherein a network state solution solved by the method is an optimal solution. According to the anti-noise-interference redundant manipulator path planning method and the system provided by the invention, with the interference of an outside noise environment, an actual motion path of a redundant manipulator can further coincide withan expected path, so that the calculating speed is greatly improved, and the method has the characteristics of high precision, fast convergence, high instantaneity, good robustness and the like.
Owner:SOUTH CHINA UNIV OF TECH

Method and apparatus for polishing a substrate having a grinded back surface

A method capable of quickly polishing an angular portion formed by a grinded back surface and a circumferential surface of a substrate without causing damages on the thin substrate is provided. The method includes rotating the substrate about its center, and pressing a polishing tape against the angular portion formed by the back surface and the circumferential surface of the substrate to polish the angular portion.
Owner:EBARA CORP

Apparatus and method for the representation of an area on the surface of a patient's body

ActiveUS20090251709A1Quick guideRapid and simple representationSurgeryTomographyLaser beamsBiomedical engineering
An apparatus for the representation of an area on the three-dimensional surface of a patient's body, with a control device which provides three-dimensional coordinates of at least one area to be represented on the surface of the patient's body, wherein the area pre-sets a desired intersection area of a radiation area on the surface of the patient's body, characterised in that at least one projection device featuring a laser is provided, by which the desired intersection area can be projected to the three-dimensional surface of the patient's body on the basis of the provided coordinates, while at least one laser beam generated by the laser can be guided along the contour of the desired intersection area sufficiently rapidly, so that the impression of a closed contour around the desired intersection area results.
Owner:LAP LASER APPLIKATIONEN

Method for controlling piezoelectric valve positioner capable of changing PWM (pulse-width modulation) duty ratio

The invention relates to a method for controlling a piezoelectric valve positioner capable of changing PWM (pulse-width modulation) duty ratio. A software system is formed by a main monitoring program module, an initializing module, a parameter self-tuning module, a valve position control module, a man-machine interaction module, an interrupt processing module, an EEPROM (electrically erasable programmable read-only memory) storage module and a watchdog module. Positive PWM duty ratio is changed by adding a five-step switch method with negative PWM into a sectional PI method or a linearization method, and when the control method is applied to small-range step control, positive PWM pulses with big duty ratio can be obtained, valve position starting process can be accelerated, the number of positive PWM pulses and adjusting time of small-range step control can be reduced, and small-range step control process can be accelerated.
Owner:HEFEI UNIV OF TECH

Robot active bracket for assisting minimally invasive surgical operation

ActiveCN101411632AOvercome the disadvantage of demanding processing and assembly requirementsGuaranteed motion accuracyMicromanipulatorSurgerySurgical operationEngineering
The invention discloses a driving support for a robot used for aiding minimally invasive surgery, wherein a base part comprises a frame and an upright post; a connecting surface which is provided with an opening is arranged on one side of the upright post; the upright post is connected with a rectilinear motion module; a lead screw and a slide seat are connected to the rectilinear motion module; an adjusting frame part comprises an adjusting frame, a guide rail seat, a first sliding guide rail which is connected to the guide rail seat, and a slider; the lower part of the guide rail seat is provided with a three-step lug boss; a bearing structure and the adjusting frame are sleeved on the central lug boss in turn; one end of the adjusting frame is inserted into the opening of the connecting surface; a beam part comprises a beam; one side of the beam is connected with the slide seat, and an input wheel and an output wheel the upper part of which is provided with a cylindrical lug boss are arranged on the other side of the beam; the first slider is fastened and fixedly connected with the input wheel; a telescopic body part comprises a telescopic seat; the bottom of the telescopic seat is provided with a hole; and the cylindrical lug boss is inserted into the hole at the bottom of the telescopic seat. The driving support guarantees the motion precision, the system rigidity and the safety of the robot.
Owner:SHANDONG WEIGAO SURGICAL ROBOT CO LTD

Robot main body system for assisting micro-wound surgical operation

The invention discloses a robot body system used for assisting miniature injury surgeries. A pedestal part of the robot body system is composed of a frame and an upright post; a crossbeam part of the robot body system is composed of a crossbeam and a first sliding track arranged on the crossbeam; wherein the upright post is connected with the crossbeam; an adjusting frame part is composed of a fixed point seat which is connected with the crossbeam and is connected with a track base which is provided with a second sliding track on which a second slipper block is arranged; wherein the second slipper block is connected with an input wheel adjusting frame; a support plate part is composed of a support plate, an input wheel and an output wheel which are respectively arranged at the left side and the right side of the support plate; a first slipper block and the input wheel adjusting frame are connected with the input wheel; a telescopic body part of the robot body system is composed of a telescopic base which is connected with the output wheel; a third sliding track provided with a third slipper block is arranged on the telescopic base, and the third slipper block is connected with an operation tool base on which operation tools are arranged. The robot body system can ensure using safety and is simple in structure, small in volume and light in weight, and provides convenience for a doctor to approach the patient quickly.
Owner:SHANDONG WEIGAO SURGICAL ROBOT CO LTD

Apparatus and method for generating facial composite image, recording medium for performing the method

Disclosed is an apparatus for generating a facial composite image, which includes: a database in which face image and partial feature image information is stored; a wireframe unit configured to apply a face wireframe to a basic face sketch image, the face wireframe applying an active weight to each intersecting point; a face composing unit configured to form a two-dimensional face model to which the wireframe is applied, by composing images selected from the database; and a model transforming unit configured to transform the two-dimensional face model according to a user input on the basis of the two-dimensional face model to which the wireframe is applied. Accordingly, a facial composite image with improved accuracy may be generated efficiently.
Owner:KOREA INST OF SCI & TECH

Apparatus and method for the representation of an area on the surface of a patient's body

ActiveUS7697147B2Quick guideRapid and simple representationSurgeryUsing optical meansLaser beamsBiomedical engineering
An apparatus for the representation of an area on the three-dimensional surface of a patient's body, with a control device which provides three-dimensional coordinates of at least one area to be represented on the surface of the patient's body, wherein the area pre-sets a desired intersection area of a radiation area on the surface of the patient's body, characterized in that at least one projection device featuring a laser is provided, by which the desired intersection area can be projected to the three-dimensional surface of the patient's body on the basis of the provided coordinates, while at least one laser beam generated by the laser can be guided along the contour of the desired intersection area sufficiently rapidly, so that the impression of a closed contour around the desired intersection area results.
Owner:LAP LASER APPLIKATIONEN

Manipulator motion planning method based on bias redefined neural network

The invention discloses a manipulator motion planning method based on a bias redefined neural network. The manipulator motion planning method based on the bias redefined neural network comprises the steps of establishing a kinematics equation of a redundant manipulator according to a model and parameters of an actual manipulator; transforming the kinematics equation of the redundant manipulator into a kinematics equation of a velocity layer, and describing the kinematics equation of the velocity layer as a smooth time-varying linear equation; acquiring a joint angle of the manipulator and endtrack information, constructing a time-varying parameter matrix according to the parameters of the manipulator, the joint angle of the manipulator and the end track information, and acquiring a corresponding time derivative; designing a bias function according to the smooth time-varying linear equation; designing a time-varying linear equation solver for a redundant robot arm by redefining a recurrent neural network with the bias function and combining the time-varying parameter matrix and the time derivative thereof; and obtaining a desired trajectory by solving the time-varying linear equation solver. According to the manipulator motion planning method based on the bias redefined neural network provided by the invention, the redundant manipulator motion planning can be carried out stablyand accurately by using the bias redefined neural network solver.
Owner:SOUTH CHINA UNIV OF TECH

Simultaneous detection, differentiation and typing system of newcastle disease and avian influenza viruses

InactiveUS20100048423A1Rapid differentiation of analytesRapid detection and differentiation and typingNucleotide librariesMicrobiological testing/measurementOligonucleotide MicroarrayZoonotic bacteria
A simultaneous detection, differentiation and typing system of Newcastle disease and avian influenza viruses is provided. The present invention provides a system, including an oligonucleotide microarray, avian virus specific probes is disposed on the oligonucleotide microarray and the avian viruses include Newcastle disease and avian influenza viruses, and avian virus nucleic acid products, hybridized with the avian virus specific probes on the oligonucleotide microarray. The present invention describes a fast, simultaneous and inexpensive approach to the detection of Newcastle disease virus (NDV) and avian influenza virus (AIV) and possesses good sensitivity and specificity among divergent viruses. The hybridization results on microarrays were clearly identified with the naked eyes, with no further imaging equipment needed. The present invention provides potential for rapid surveillance and differential diagnosis of these two important zoonoses in both wild and domestic birds.
Owner:NAT INST FOR ANIMAL HEALTH COUNCIL AGRI EXECUTIVE YUAN

Multi-level hybrid vulnerability automatic mining method

The invention belongs to the technical field of computers, and particularly relates to a multi-level hybrid vulnerability automatic mining method, which comprises the following steps: S1, obtaining pointer distribution and assignment processes in a program by utilizing pointer analysis through a static analysis technology, and recording memory address positions pointed by all pointers; obtaining adestination operand of the CMP type instruction by using an alias analysis technology so as to clarify a jump address of the target program; and S2, realizing instrumentation of the monitoring code to the key position of the target program through an intermediate code static instrumentation technology. According to the invention, the binary executable program is translated into the middle-layer representation language of the compiler, and compared with the binary executable program, the middle-layer representation language source code obtained through processing of the method has more semantic information; compared with C / C + + language analysis, the static analysis technology for the LLVM IR intermediate representation language can realize finer-grained static semantic information extraction during compiling.
Owner:GUANGZHOU UNIVERSITY

Method for grabbing object through mobile manipulator on basis of GPS and binocular vision positioning

The invention discloses a method for grabbing an object through a mobile manipulator on the basis of a GPS and binocular vision positioning, and belongs to the automation field. The mobile manipulator moves to the position nearby the target object according to target object spatial position information obtained through the GPS, three-dimensional position information of the target object is obtained on the basis of binocular vision, the mobile manipulator moves to the position nearby the target object, the target object is located within the operating range of the mobile manipulator, a mobile manipulator end effector quickly approaches to the target object on the basis of visual feedforward, the mobile manipulator end effector is controlled to be precisely aligned to the target object on the basis of visual feedback, and finally the mobile manipulator end effector is controlled to conduct grabbing action. According to the method, GPS positioning information is utilized, the target object can be searched for within a large range, the time consumed by the mobile manipulator end effector in approaching to the target object is shortened on the basis of visual feedforward, and alignment precision of the mobile manipulator end effector and the target object is improved by means of visual feedback.
Owner:SHANDONG UNIV OF TECH

Hand machine tool with brushed motor

The invention relates to a hand-held power tool 10 which comprises a longilineal motor housing 16 that serves as a handle, which accommodates an electric collector motor 50. The interior of the motorhousing is accessible via a servicing opening 26 of the motor housing 16, which is closable by a cover 22, so as to be more safe in the electric field. The cover has an indentation 29 on its outside surface and far away from the outer edge for engagement of a tool (58) for opening the cover.
Owner:ROBERT BOSCH GMBH

Optimization method of blending rate of coal for coking based on modified differential evolution algorithm

The invention relates to the field of coal blending, particularly to an optimization method of a blending rate of coal for coking based on the modified differential evolution algorithm. The optimization method is combined with the requirements of the technology of coal blending for coking, an optimization model of a coal blending ratio, which uses the mass of blended coal and the mass of coke as constraint conditions and uses coal blending cost as an objective function, is established according to the non-linear relationship between single coal and blending coal, and between blending coal and coke, and the mass index of each single coal. The optimization method further provides a modified differential evolution algorithm so as to perform optimization solution on the model. The optimization method disclosed by the invention is reliable and stable, is high in calculating precision, and is fast in convergence. Through the adoption of the optimization method, the problem that the accuracy of the blending rate confirmed by manual work in the prior art during coal blending for coking is not high is effectively solved, so that when the demands of users for the mass of coke are guaranteed, the coal blending cost is reduced to the maximum extent.
Owner:SHANXI TAIGANG STAINLESS STEEL CO LTD
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