The invention discloses a traditional Chinese medicine composition for treating climacteric syndrome. The traditional Chinese medicine composition is prepared from the following crude drugs: radix bupleuri, radix paeoniae alba, radix curcumae, dogwood, common yam rhizome, mulberry fruit, spina date seed, light wheat, tuber fleeceflower stem, keel, oyster, lotus nut, lily, prepared rehmannia root, rhizoma anemarrhenae, astragalus membranaceus, radix ophiopogonis, schisandra chinensis, fruit of Chinese wolfberry, seed of Chinese dodder, tuckahoe, bighead atractylodes rhizome, root bark of the peony tree, corbicula, soybean sprout, tortoise shell, laportea, bayuezha (Chinese character), filbert, and nacre mother of pearl. The traditional Chinese medicine composition can treat the climacteric syndrome, and can soothe the liver and regulate qi, nourish yin and invigorate the spleen, and nourish yin and yang. The technology has the advantages of being convenient to dose, through in affected part, strong in targeting property, low in cost and the like; and a drug is easily prepared. The traditional Chinese medicine composition adopts different drug properties of traditional Chinese medicinal materials; scientific formulation is carried out; and an ideal treatment effect can be achieved. The traditional Chinese medicine composition is safe, and free of toxic and side effects, can replenish the vital essence and remove heat in combination of oral administration and external application, and can eliminate dampness and dredge channels, and remove pain.