The invention discloses a large, thick, high-strength and high-
toughness TMCP type steel plate and a production method thereof. The large, thick, high-strength and high-
toughness TMCP type steel plate is composed of, by weight, 0.06%-0.08% of C, 0.20%-0.40% of Si, 1.40%-1.50% of Mn, 0.015% or less of P, 0.005% or less of S, 0.020-0.030% of Nb, 0.030%-0.050% of Alt, the balance Fe and inevitable impurities and 0.20% or less of Pcm. According to the steel plate, the components are simple, only a proper amount of microalloy Nb is added, and the precious elements such as V, Ti and Ni are not added; production cost is low, and the probability of large-scale production is increased. The steel plate is of a mixed structure mainly containing 
bainite, ferrite, 
pearlite and 
martensite and has a good comprehensive 
mechanical property; the steel plate is better in matching of the components and the strength and 
toughness, and it is guaranteed that the steel plate has the excellent comprehensive 
mechanical property; particularly, the 
impact performance of half of the plate in the thickness direction is good at the low temperature of minus 40 DEG C, and the method can be widely used for producing low-temperature-resistant building steel and 
engineering steel used in extremely 
cold climate. The method has the advantages that the production cost is low, and the technique is simple; the performance of products is excellent, and the comprehensive 
mechanical property of the products is stable.