The application relates to a kind of isoprenyl
xanthone compounds and preparation method and application thereof, relate to the medical technical field, comprising the following steps: 1) after
cutting, cold extraction of the whole
herb of
Eupatorium fortunei, filtrate is collected and concentrated under reduced pressure to obtain extract;2) the extract obtained in step 1) is chromatographed by
silica gel column,
gradient elution is carried out, and 3 fractions Fr.A-Fr.C are obtained;3) fraction Fr.A in step 2) is chromatographed by MCI column,
gradient elution is carried out, and 6 fractions Fr.A1-Fr.A6 are obtained;4) fraction Fr.A3 in step 3) is chromatographed by
silica gel column,
gradient elution is carried out, and 11 fractions Fr.A3.1-Fr.A3.11 are obtained;5) compound is prepared and separated by HPLC
high performance liquid chromatography method in fraction Fr.A3.10 in step 4), for preparing the
drug for resisting Alzheimer
disease.