The invention provides an aviation wire harness end laser processing equipment, and relates to the field of aviation wire harness processing. The equipment comprises a bottom plate, a wire clamping mechanism, a rotating mechanism, a laser mechanism and an optical system arranged in the rotating mechanism, wherein the wire clamping mechanism, the rotating mechanism, and the laser mechanism are arranged on the bottom plate in sequence. Laser is adopted for machining the aviation wire harness end, an optical system is driven by a rotating mechanism to surround a machined aviation wire harness byone circle mainly based on a nanosecond short-pulse laser with the wavelength of 405 nm, and high-precision and high-efficiency aviation wire harness end machining serves as the target. And the processing of wire stripping, windowing, longitudinal cutting, regional evaporation ablation and the like of the aviation wire harness end is realized. According to the invention, the wire taking PTFE and PVC as insulating materials is taken as a processed material, the processing time is less than 5s, the fixed-length precision is not more than 0.2 mm, the processing length is 3-30mm, and the wire coreV is physically damaged, so that the equipment is compact in structure, reliable in processing quality, high in processing efficiency, high in processing precision, small in occupied space and convenient to move.