The invention relates to a graphene pressure sensor comprising a nanofilm, interconnected electrodes, leading columns, a base piece, a package housing, a ceramic base, and sealing rings. Detection is carried out by using the nanofilm, the base piece, and the interconnected electrodes. The nanofilm is formed by an upper boron nitride layer, a lower boron nitride layer, and a graphene layer formed between the upper boron nitride layer and the lower boron nitride layer and is arranged at the lower surface of the base piece; the upper part of the base piece is etched to form a recessed structure and the upper part of the base piece and the ceramic base are in metal bonding to form an oxygen-free vacuum cavity to isolate the nanofilm from the external world so as to provide oxygen-free protection. The interconnected electrodes are formed by bonding of interconnected salient points with interconnected welding plates. With the leading columns, a detection unit is connected externally. The boron nitride-graphene-boron nitride nanofilm not only serves as a functional material of the sensor but also serves as a structural material. The sensor that is capable of work in a high-temperature environment with a high temperature of 1000 DEG C and has advantages of high repeatability, reliability, good acid and alkali-resistant and corrosion-resistant performances can be applied to dynamic and static high-temperature testing environments; and the high-temperature zone is improved obviously.