The application provides a multi-leaf
collimator assembly, a radiotherapy device and a leaf locking method. The multi-leaf
collimator assembly comprises a frame and at least two spaced-apart leaf collimators; each leaf
collimator is slidably connected to the frame and can slide in a first direction; the
assembly further comprises a driving device and a locking member connected to the driving device; when the leaf collimator slides into an initial position in the frame, the driving device can drive the locking member to abut against the leaf collimator in a second direction, and the leaf collimator abuts against the frame; the first direction and the second direction are both perpendicular to the thickness direction of the leaf collimator, and the first direction and the second direction are not parallel. The driving device can drive the locking member to abut against the leaf collimator, so that the leaf collimator abuts against the frame, thereby fixing the leaf collimator by using the friction between the leaf collimator and the frame and the friction between the leaf collimator and the locking member, and thereby avoiding mechanical collision of the leaf collimator or weakening the mechanical collision intensity during the acceleration and deceleration stages of high-speed rotation of the multi-leaf collimator assembly.