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30results about How to "Avoid the decline of drug efficacy" patented technology

External traditional Chinese medicine bag prescription, medicine bag and using method thereof

The invention discloses an external traditional Chinese medicine bag prescription, a medicine bag and a using method thereof, and belongs to the field of traditional Chinese medicines. The medicine bag prescription consists of the following components in parts by weight: 10-30 parts of dried ginger, 5-15 parts of herba menthae, 10-20 parts of rhizoma curcumae longae, 10-20 parts of radix angelicae, 5-15 parts of cassia twig, 2-10 parts of radix angelicae sinensis, 2-10 parts of rhizoma ligustici wallichii, 2-10 parts of herba asari cum radice and 50-90 parts of folium artemisiae argyi. The traditional Chinese medicine bag, which is manufactured on the basis of the prescription, is relatively strong in effects of promoting blood circulation and removing stasis, diminishing inflammation and alleviating pain, warming and activating meridians, dispelling cold and the like through a synergistic effect among the various components, and the traditional Chinese medicine bag, in combination with a massaging effect, is capable of promoting blood circulation and promoting metabolism through hot compress; the traditional Chinese medicine bag is relatively high in comfort degree and can be widely applied to health care industry as well as to the treatment of osteoarthropathy such as cervical spondylosis, lumbar spondylosis and the like and diseases of deficiency-cold; meanwhile, the traditional Chinese medicine bag has the advantages of being low in cost, convenient to use, high in safety, free from side effects, large in operating area, rapid to take effects, significant in curative effect and the like; and the using method provided by the invention is simple to operate, easily available in raw materials and low in cost, and conforms to the market demands of traditional Chinese medicine and the health care industry.
Owner:佛山健翔医院有限公司

Dimethomorph dispersible oil suspending agent and preparation method and application thereof

The invention belongs to the technical field of pesticide formulation processing and specifically relates to a dimethomorph dispersible oil suspending agent and further discloses a preparation method and application thereof. The oil suspending agent disclosed by the invention is prepared from the raw materials of a dimethomorph original material, a non-ionic surface active agent, an anionic surface active agent, a cosurfactant, an adhesion and absorption enhancer, a stabilizer, an enzyme modifier and a dispersion medium. According to the dispersible oil suspending agent disclosed by the invention, the adhesion and absorption enhancer and the enzyme modifier are added to modify a product based on existing oil suspending agent preparation raw material; added catalase and/or cellulase are beneficial to product formulation polymerization and very good modifying treatment on a suspension dispersing situation; the prepared oil suspending agent has very good suspension performance, furthermore, a release effect of effective ingredients of the oil suspending agent is better, and prevention performance of the oil suspending agent to diseases and pests is better. In addition, according to the oil suspending agent disclosed by the invention, polyglutamic acid is more preferably added as a preparation raw material; suspension performance and pesticide effect playing performance are further improved, and a modifying effect is better.
Owner:INST OF PLANT PROTECTION CHINESE ACAD OF AGRI SCI

Difenoconazole dispersible oil suspending agent and preparation method and application thereof

The invention belongs to the technical field of pesticide formulation processing and particularly relates to a difenoconazole dispersible oil suspending agent and a preparation method and application thereof. The oil suspending agent is prepared by original difenoconazole, nonionic surfactant, anionic surfactant, cosurfactant, an adhering absorption enhancer, a stabilizer, an enzyme modifier and a dispersion medium. The dispersible oil suspending agent has the advantages that the adhering absorption enhancer and the enzyme modifier are added on the basis of existing raw materials for preparing the oil suspending agent to perform product modification, added catalase and / or cellulase can helpfully well modify the polymerization and suspending and dispersion conditions of the product formulation, the prepared oil suspending agent is good in suspending performance, the release effect of the effective components of the oil suspending agent is good, and the oil suspending agent is good in preventing effect on diseases and pests; in addition, the polyglutamic acid is preferably added into the oil suspending agent to serve as the preparation raw material, the suspending performance and pesticide effect of the oil suspending agent can be further increased, and a good modification effect is achieved.
Owner:INST OF PLANT PROTECTION CHINESE ACAD OF AGRI SCI

Double-component compound medicine for treating hair oil and scurf and preparing method thereof

The invention discloses a double-component compound medicine for treating hair oil and scurf and a preparing method thereof. The compound medicine comprises a first component and a second component. The first component is prepared from a first raw medicinal material, and the first raw medicinal material is prepared from, by weight, 80-150 parts of tea seed cakes. The second component is prepared from second raw medicinal materials, and the second raw medicinal materials are prepared from, by weight, 20-80 parts of angelica sinensis, 30-60 parts of fleece-flower roots, 35-80 parts of folium mori, 40-80 parts of cacumen biotae, 10-25 parts of broadleaf holly leaves, 15-35 parts of lemons and 180-270 parts of fresh ginger. The compound medicine can effectively treat hair oil and scurf, rapidly takes effect and is high in curing rate, stable in treatment effect and free of relapsing. The invention further provides the preparing method of the compound medicine. The preparing method includes the steps that the tea seed cakes are soaked, and the first component is obtained; after the angelica sinensis, the fleece-flower roots, the folium mori, the cacumen biotae, the broadleaf holly leaves and the lemons are soaked, solid-liquid separation is carried out, liquid medicine is obtained, the fresh ginger is smashed, the smashed fresh ginger is added into the liquid medicine, and the second component is obtained. The preparing method is simple and practicable, and the treatment effect of the compound medicine prepared with the preparing method is better.
Owner:徐正花

Traditional Chinese medicine powder for treating pelvic peritonitis

InactiveCN104922589AEasy to useSolve the lesionPowder deliveryAntipyreticRadix AconitiPelvic peritonitis
The invention belongs to the field of traditional Chinese medicine preparations and particularly relates to traditional Chinese medicine powder for treating pelvic peritonitis. The traditional Chinese medicine powder comprises the following components in parts by weight: 10-20 parts of radix astragali preparata, 5-15 parts of processed radix aconiti carmichaeli, 2-8 parts of herba lycopi, 1-5 parts of rhizoma corydalis, 25-35 parts of radix paeoniae alba, 5-15 parts of salivia chinensis, 5-15 parts of coptis chinensis, 25-35 parts of herba lysimachiae, 5-15 parts of stir-baked fructus gardenia, 5-15 parts of elecampane, 5-15 parts of immature bitter orange, 1-5 parts of stir-baked squama manitis, 10-20 parts of fructus liquidambaris, 10-20 parts of red paeonia, 10-20 parts of large cortex cinnamomi imported from Vietnam and 10-20 parts of curcuma zedoary. The traditional Chinese medicine powder has the beneficial effects as follows: on the one hand, the powder integrates various traditional Chinese medicine functions, all the traditional Chinese medicines complement one another and benefit to one another, and the pathogenetic focuses of patients are fundamentally solved; on the other hand, all the raw materials are low in cost, so that the traditional Chinese medicine powder is suitable for large-scale production; more patients can take the traditional Chinese medicine powder.
Owner:JINAN ZHENGQI BIOTECHNOLOGY CO LTD

Sewage purification device

The invention relates to the technical field of sewage treatment, and particularly relates to a sewage purification device. The device comprises a device body, a purification chamber is arranged in the device body, a through hole is dug in the top of the purification chamber, a telescopic arm penetrates through the through hole, the top end of the telescopic arm is connected with a rotating motor,the bottom end of the telescopic arm extends towards two sides to form a stirring rod, a plurality of medicine boxes are arranged at the top of the device body side by side, a medicine doser is embedded in the top end of the purification chamber, and the medicine doser is embedded in the outer side of the telescopic arm. The arrangement of the plurality of medicine boxes and a plurality of medicine adding ports makes another medicine added after one medicine is fully dissolved, so medicine effect reduction caused by the mutual reaction of the medicines is avoided, the medicine reaction effectis good, and the unnecessary cost is substantially reduced; and the medicines and the sewage are completely reacted through a stirrer capable of moving in the vertical direction, so secondary pollution of insufficient sewage purification discharge to the environment is prevented, and the use is wide.
Owner:NINGHUA KUANXIN SCI & TECH SERVICE CO LTD

Yin-yang plaster

ActiveCN101837025ATargetability of Well Classified PenetrationImprove permeabilityAntipyreticAnalgesicsMedicinePercutaneous absorption
The invention relates to a yin-yang plaster. The yin-yang plaster comprises a plaster body and a back lining layer, wherein the plaster body comprises matrix, bulk pharmaceutical chemicals and a percutaneous absorption promoter. The yin-yang plaster is characterized in that the plaster body consists of a yin plaster body and a yang plaster body which are mutually closed and are pasted on the back lining layer, wherein the weight ratio of the yin plaster body to a white matrix vector to growing, yin and cold kinds of the bulk pharmaceutical chemicals is 10:3; and the weight ratio of the yang plaster body to a black matrix vector to antiphlogistic, yang and hot kinds of the bulk pharmaceutical chemicals is 10:3. The white matrix vector component contains 90 to 95 percent of white matrix and 5 to 10 percent of borneol; the black matrix vector component contains 90 to 95 percent of black matrix contained and 5 to 10 percent of musk; the white matrix component contains 10 percent of white oil-soluble pigment and 90 percent of medical pressure-sensitive adhesive; and the black matrix component contains 10 percent of black oil-soluble pigment and 90 percent of medical pressure-sensitive adhesive. The yin-yang plaster has a shape of two fishes in a Taiji diagram, a symmetrical double semi-circular shape or a symmetrical square shape. The yin-yang plaster has the following advantages of obvious effects of curing diseases and removing pain, and long medicament effect.
Owner:天津世济生物工程有限公司

Clinical ophthalmology multifunctional therapeutic apparatus

InactiveCN114042243AHeadache reliefDifferent treatment effectsMedical devicesEye-masksOphthalmologyCurative effect
The invention discloses a clinical ophthalmology multifunctional therapeutic apparatus, which comprises a multifunctional therapeutic apparatus main body, a therapeutic apparatus controller, a medicine bag placing drawer, a medicine bag heating layer, a therapeutic eyeshade and an electrotherapy patch, the electrotherapy patch is connected to the multifunctional therapeutic apparatus main body, and the electrotherapy patch is attached to temples to bioelectrically stimulate the temples, so that the head is massaged , and headaches caused by eye problems are effectively relieved. Two medicine bag boxes are arranged on the multifunctional therapeutic apparatus body, medicine bags with different curative effects can be placed in the medicine bag boxes according to treatment requirements, so that different treatment effects are achieved, the medicine bags can be replaced at any time, and a medicine bag heating layer is arranged between the therapeutic apparatus controller and the medicine bag placing drawer. The medicine bag is heated through the medicine bag heating layer, the treatment time is shortened, meanwhile, the medicine effect of the medicine bag is exerted to the maximum degree, the treatment effect is guaranteed, and the clinical ophthalmology multifunctional therapeutic apparatus is small and exquisite in structure, capable of being carried at will, fixed through the bandage, convenient for a patient to independently wear and easier to popularize.
Owner:PUYANG ANYANG REGIONAL HOSPITAL

Antibacterial, anti-infection and hemostatic elastic bandage and preparation method thereof

The invention discloses an antibacterial, anti-infection and hemostatic elastic bandage and a preparation method thereof, and particularly relates to the technical field of medical bandages. The antibacterial, anti-infection and hemostatic elastic bandage comprises base cloth and an adhesive coating two sides of the base cloth, wherein weft yarns of the base cloth are all cotton yarns, and warp yarns of the base cloth are spandex yarns. The antibacterial and anti-infection effects and the hemostatic effect of the elastic bandage can be effectively improved; common threewingnut root dispels wind, eliminates dampness, promotes blood circulation to remove meridian obstruction, relieves swelling and pain, kills parasites, diminishes inflammation and removes toxic substances, aizoon stonecrop herb can shorten blood coagulation time and has the effects of calming and reducing blood pressure, herba ecliptae has the effects of inhibiting bacterial growth, stopping bleeding and improving cardiovascular system functions, resina draconis has the effects of resisting inflammation, inhibiting bacteria and resisting thrombus, and nano-silver colloid has an excellent antibacterial characteristic and can effectively enhance the antibacterial effect of the bandage; and polystyrene magnetic microspheres can be coupled with protein molecules such as antibodies and the like to prepare immunomagnetic beads, so that the antibacterial, anti-infection and hemostatic effects of the bandage can be effectively enhanced.
Owner:QINGDAO LI KANG YUAN MEDICAL DEVICE

Traditional Chinese medicine potion treatment device

The invention belongs to the technical field of processing of traditional Chinese medicine potion, and particularly relates to a traditional Chinese medicine potion treatment device. The device comprises a shell, a medicine carrying assembly, supporting assemblies, a liquid discharging assembly and a cover plate assembly, wherein supporting legs are fixedly installed on the shell, a water inlet pipe is installed on the shell, a plurality of heating devices are fixedly arranged on the inner wall of the shell, the medicine carrying assembly is located in the shell, a liquid discharging groove is formed in the bottom of the shell, the liquid discharging assembly is fixedly connected with the liquid discharging groove, the supporting assemblies are located on the two sides of the shell and are connected with the medicine carrying assembly, and the cover plate assembly is installed at the top of the shell. The device is used for solving the problems that when existing decocting equipment is used for decocting a traditional Chinese medicine potion, due to mass production, the amount of medicinal materials needing to be placed into the device is large, more time is consumed when the medicinal materials are placed into the device, and after decocting is completed, the temperature of liquid medicine is high, and the medicinal materials are inconvenient to take out.
Owner:杨玲玲

Traditional Chinese medicine powder for treating dysmenorrhea

The invention belongs to the field of traditional Chinese medicine, particularly relates to a traditional Chinese medicine powder for treating dysmenorrhea. The traditional Chinese medicine powder is prepared from the following components in part by weight: 10-20 parts of radix astragali preparata, 5-15 parts of processed radix aconiti lateralis preparata, 2-8 parts of herba lycopi, 1-5 parts of rhizoma corydalis, 25-35 parts of radix paeoniae alba, 5-15 parts of cortex moutan radicis, 5-15 parts of rhizoma coptidis, 25-35 parts of herba lysimachiae, 5-15 parts of radix gentianae, 5-15 parts of stir-baked fructus gardeniae, 10-20 parts of cortex moutan radicis, 25-35 parts of herba artemisiae scopariae, 15-25 parts of flos lonicerae, 20-30 parts of processed radix aconiti lateralis preparata, 5-15 parts of radix aucklandiae, 5-15 parts of fructus aurantii immaturus, 1-5 parts of stir-baked squama manitis, 10-20 parts of fructus liquidambaris, 10-20 parts of radix paeoniae rubra, 10-20 parts of cortex cinnamomi, and 10-20 parts of rhizoma zedoariae. According to the invention, the prepared traditional Chinese medicine powder can achieve the benefits that on one hand, efficacies of a plurality of traditional Chinese medicines are integrated, and the traditional Chinese medicines complement each other and benefit each other, so that the nidi of patients are solved fundamentally; on the other hand, all raw materials are low in costs and are suitable for mass production, so that the traditional Chinese medicine powder is convenient for more patients to use.
Owner:JINAN ZHENGQI BIOTECHNOLOGY CO LTD

A kind of dimethomorph dispersible oil suspension concentrate and its preparation method and application

The invention belongs to the technical field of pesticide formulation processing and specifically relates to a dimethomorph dispersible oil suspending agent and further discloses a preparation method and application thereof. The oil suspending agent disclosed by the invention is prepared from the raw materials of a dimethomorph original material, a non-ionic surface active agent, an anionic surface active agent, a cosurfactant, an adhesion and absorption enhancer, a stabilizer, an enzyme modifier and a dispersion medium. According to the dispersible oil suspending agent disclosed by the invention, the adhesion and absorption enhancer and the enzyme modifier are added to modify a product based on existing oil suspending agent preparation raw material; added catalase and / or cellulase are beneficial to product formulation polymerization and very good modifying treatment on a suspension dispersing situation; the prepared oil suspending agent has very good suspension performance, furthermore, a release effect of effective ingredients of the oil suspending agent is better, and prevention performance of the oil suspending agent to diseases and pests is better. In addition, according to the oil suspending agent disclosed by the invention, polyglutamic acid is more preferably added as a preparation raw material; suspension performance and pesticide effect playing performance are further improved, and a modifying effect is better.
Owner:INST OF PLANT PROTECTION CHINESE ACAD OF AGRI SCI

Multifunctional pesticide spraying device

The invention relates to the technical field of planting, in particular to a multifunctional pesticide spraying device. The multifunctional pesticide spraying device comprises a box body, a first sliding groove is formed at the upper side of the box body, a set of moving devices are installed at the lower side of the box body, a first pesticide spraying device is arranged in the first sliding groove, and a recycling groove is formed at the upper side of the box body. The recycling groove is arranged corresponding to the first pesticide spraying device, accurate control hydraulic cylinders arefixed to the two opposite sides of the box body, a fixing frame is arranged at the outer side of each accurate control hydraulic cylinder, and each fixing frame is fixed through a set of fixing nuts.The 180-degree spraying coverage rate of crop is completed through the first pesticide spraying device, and the pesticide using effect is greatly improved; and horizontal spraying operation on the crop is completed through a second pesticide spraying device, and the spraying area of the second pesticide spraying device is adjusted by adjusting the horizontal height of a connecting column, so thatthe pesticide spraying device can conduct spraying operation on the root base parts of the crop, and the pesticide effect exertion effect is improved.
Owner:安徽军松现代农业科技有限公司

Yin-yang plaster

ActiveCN101837025BTargetability of Well Classified PenetrationImprove permeabilityAntipyreticAnalgesicsMedicinePercutaneous absorption
The invention relates to a yin-yang plaster. The yin-yang plaster comprises a plaster body and a back lining layer, wherein the plaster body comprises matrix, bulk pharmaceutical chemicals and a percutaneous absorption promoter. The yin-yang plaster is characterized in that the plaster body consists of a yin plaster body and a yang plaster body which are mutually closed and are pasted on the backlining layer, wherein the weight ratio of the yin plaster body to a white matrix vector to growing, yin and cold kinds of the bulk pharmaceutical chemicals is 10:3; and the weight ratio of the yang plaster body to a black matrix vector to antiphlogistic, yang and hot kinds of the bulk pharmaceutical chemicals is 10:3. The white matrix vector component contains 90 to 95 percent of white matrix and5 to 10 percent of borneol; the black matrix vector component contains 90 to 95 percent of black matrix contained and 5 to 10 percent of musk; the white matrix component contains 10 percent of white oil-soluble pigment and 90 percent of medical pressure-sensitive adhesive; and the black matrix component contains 10 percent of black oil-soluble pigment and 90 percent of medical pressure-sensitive adhesive. The yin-yang plaster has a shape of two fishes in a Taiji diagram, a symmetrical double semi-circular shape or a symmetrical square shape. The yin-yang plaster has the following advantages of obvious effects of curing diseases and removing pain, and long medicament effect.
Owner:天津世济生物工程有限公司

Swelling and pain relieving ointment and preparation method thereof

The invention discloses a swelling and pain relieving ointment and a preparation method thereof, and belongs to the field of traditional Chinese medicine preparations. The swelling and pain relievingointment is prepared from the following raw materials in parts by weight: 3-6 parts of lithospermum oil, 2 to 7 parts of a thickening agent and 10 to 15 parts of calcined gypsum. During manufacturing,lithospermum is fried with vegetable oil, the obtained lithospermum oil is uniformly mixed with the thickening agent and the calcined gypsum according to a set ratio to obtain a paste body. The swelling and pain relieving ointment disclosed by the invention has relatively strong effects of promoting blood circulation and removing blood stasis, diminishing inflammation and relieving pain, warmingchannels and dredging collaterals, dispelling cold and the like through synergistic interaction of all the components, can be used for effectively treating various types of joint acute and habitual sprains, can relieve rapidly and effectively the pain of a sprained person, and can be used for rapidly and effectively curing acute sprains of athletes due to trainings and matches; through the ointment, the pain of the muscle and bone injury process is relieved rapidly and timely on the maximum degree, and the effective rate of the ointment absorption is improved.
Owner:梁肆生

A hand-held high-efficiency slicing machine for traditional Chinese medicine

The invention discloses a handheld traditional Chinese medicine efficient slicer, which comprises a handheld box and a cutting box. Fixing chutes are arranged in both sides of the inner wall of the left part of the handheld box, sliders are fixed in the fixing chutes in a sliding manner, the cutting box is fixedly connected to the left side of the sliders, a clamping seat is fixedly connected to the right inner wall of the cutting box, a plurality of wire clamping grooves are arranged in the clamping seat, clamping bolts are arranged at the left side of the cutting box, a wire clamping block is fixedly connected to the right side of the upper end of the clamping bolts, a plurality of wire clamping grooves matched with the clamping seat are arranged in the upper end of the clamping block, and a cutting steel wire is arranged between the wire clamping grooves in two sides; and an electric motor is fixedly connected in the middle of the handheld box and is fixedly connected to the sliders, and a storage battery is further fixedly connected in the handheld box. The handheld traditional Chinese medicine efficient slicer is small in size and convenient to use, high in efficiency and good in effect of slicing traditional Chinese medicine, and is suitable for various pharmacies and hospitals.
Owner:内蒙古弘图药业有限公司

Ointment capable of eliminating swelling and alleviating pain and preparation method of ointment

The invention discloses ointment capable of eliminating swelling and alleviating pain and a preparation method of the ointment, and belongs to the field of traditional Chinese medicine preparations. The ointment capable of eliminating swelling and alleviating pain is prepared from the following raw materials in parts by weight: 3 to 6 parts of radix lithospermi oil, 2 to 7 parts of a thickening agent and 10 to 15 parts of calcined gypsum. In a production process, after radix lithospermi is fried with vegetable oil, the obtained radix lithospermi oil, the thickening agent and the calcined gypsum are uniformly mixed according to a pre-set ratio to obtain the ointment. The ointment capable of eliminating swelling and alleviating pain, disclosed by the invention, has relatively high effects of promoting blood circulation and removing blood stasis, diminishing inflammation and alleviating pain, warming and activating meridian, dispelling cold and the like through a coordinated matching effect of all the components; the ointment can be used for effectively treating various types of acute and habitual sprains of joints and rapidly and effectively alleviating pains of people with sprains, and can be used for rapidly and effectively healing acute sprains of athletes, caused by trainings and competitions; after the ointment is used, pains in a muscle and bone injury process are rapidly alleviated in time to the greatest extent, and the effective rate of ointment absorption is improved.
Owner:佛山健翔医院有限公司

A two-component compound medicine for treating dandruff and dandruff and preparation method thereof

The invention discloses a double-component compound medicine for treating hair oil and scurf and a preparing method thereof. The compound medicine comprises a first component and a second component. The first component is prepared from a first raw medicinal material, and the first raw medicinal material is prepared from, by weight, 80-150 parts of tea seed cakes. The second component is prepared from second raw medicinal materials, and the second raw medicinal materials are prepared from, by weight, 20-80 parts of angelica sinensis, 30-60 parts of fleece-flower roots, 35-80 parts of folium mori, 40-80 parts of cacumen biotae, 10-25 parts of broadleaf holly leaves, 15-35 parts of lemons and 180-270 parts of fresh ginger. The compound medicine can effectively treat hair oil and scurf, rapidly takes effect and is high in curing rate, stable in treatment effect and free of relapsing. The invention further provides the preparing method of the compound medicine. The preparing method includes the steps that the tea seed cakes are soaked, and the first component is obtained; after the angelica sinensis, the fleece-flower roots, the folium mori, the cacumen biotae, the broadleaf holly leaves and the lemons are soaked, solid-liquid separation is carried out, liquid medicine is obtained, the fresh ginger is smashed, the smashed fresh ginger is added into the liquid medicine, and the second component is obtained. The preparing method is simple and practicable, and the treatment effect of the compound medicine prepared with the preparing method is better.
Owner:徐正花

Incense-fuming solid-state formulation for treating nasitis and reagent bottle equipped with same

The invention relates to an aromatherapy solid-phase preparation for treating rhinitis, which can be transformed into a solid phase and a liquid phase, and also relates to a reagent bottle containing the aromatherapy solid-phase preparation for treating rhinitis. The present invention relates to an aromatherapy solid-phase preparation for treating rhinitis and a reagent bottle containing the solid-phase preparation, which have the following advantages: (1) fat-soluble; (2) outsourcing phospholipids as body components, compatible with the body (3) When used as a fumigant, the drug can be slowly leaked only by body temperature, and the double-layer cover controls the volatilization speed of the drug; (4) By changing the external temperature, the phospholipid can be used to control and slow the release of the drug (5) As a nasal drop, it has a large specific surface area, which increases its contact area with the nasal mucosa and relatively prolongs its contact time with the nasal mucosa; (6) The nasal drop is nanoscale; (7) ) has better flexibility and deformability; (8) has better stability, and it avoids the decline of the drug effect due to the volatilization of Magnolia magnolia volatile oil.
Owner:XIN HUA HOSPITAL AFFILIATED TO SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE
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