The invention provides an A3.5 B05 grade autoclaved aerated concrete block made of quartz weathered sand. The high-performance A3.5 B05 grade autoclaved aerated concrete block is made by using the quartz weathered sand, cement, quicklime, industrial waste phosphogypsum, aluminum powder paste and water as raw materials. The dry density of the block is 509kg/m<3>, the average cubic compressive strength of the block is 3.6MPa, the single component minimum of the block is 3.2Mpa, the split-to-compression ratio is 0.20, the mass loss after freezing is 2.8%, the strength after freezing is 3.1Mpa, the heat conduction coefficient (dry state) is 0.1251W/(m.K), the drying shrinkage value (standard process) is 0.32mm/m, and the qualified rate is greater than 98%. The method has the advantages of reasonable treatment of raw materials, scientific formula calculation, concise production flow, recycling of production wastes. The block is a novel energy saving and environmental protection wall material, and can be industrially produced.