The invention belongs to the technical field of welding devices and discloses a pulse negative pressure laser enhanced-type lock hole TIG welding device. The pulse negative pressure laser enhanced-type lock hole TIG welding device comprises a hollow tungsten electrode, a tungsten electrode clamp, a vacuum negative pressure pipe, an insulation air pipe, a laser, a laser fixing frame, high transmittance glass, a welding gun outer body, an electric conductor, a lantern ring, a transferring rod, a transferring head, an electric conducting rod insulation sleeve, an air transferring head, a vacuum negative pressure connector, an upper insulator, a lower insulator, an air hood, an upper nut, a lower end nut, a locking nut, a pulse solenoid valve, a vacuum negative pressure meter, a pressure storage tank and an air pump. According to the technical scheme, stability of the welding process is ensured, the lock hole TIG welding quality is improved so that the weld joint shape is more reasonable,and the welding process is more stable; meanwhile the electric arc shape is effectively restrained, the weld joint heat-affected zone is reduced, and the electric arc penetrating power is reinforced;an electric arc generates the oscillation effect, the weld joint structure is refined; and the laser reinforcing effect is matched, the weld joint depth-to-width ratio is optimized, weld joint formingis more aesthetic, and promotion and optimization of the weld joint quality and the welding efficiency are achieved.