A holding and support assembly for a winding mandrel in a machine for winding plastic film onto rolls, said machine comprising a winding mandrel positioned between two uprights (12, 13), wherein A first upright (12) carries a rotating plate (14) that cantileverly supports three mandrels (16, 17, 18) and a central shaft (15) that integrally constitute A winding reel, wherein the other end of the central shaft (15) is supported at the second column (13), wherein, corresponding to the free end of the central shaft (15), a star plate (19) is provided, said The star plate has three support arms through each free end of the three mandrels (16, 17, 18) of the corresponding toggle lever mechanism (21, 22, 25) consisting of The actuator (30) is driven and carried on a rod (20) articulated relative to the star plate (19), said rod being in turn driven by another actuator (32) on the corresponding spindle (16, 17 or 18) swings between an operational blocking position for releasing the corresponding mandrel (16, 17, 18) and a rest position.