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This utility model discloses a biological tissue homogenizer, specifically relating to the field of cell tissue homogenization technology. It includes a homogenization mechanism comprising a base and a support frame. A placement mechanism is slidably connected above the support frame, and a hydraulic cylinder is mounted above the support frame. This utility model achieves automatic cleaning and surface moisture adsorption of the homogenizing rod through the coordinated operation of the placement mechanism, cleaning mechanism, wiping mechanism, connecting rope, and water tank. The placement mechanism and cleaning mechanism are linked by guide wheels and slide rails, allowing for simultaneous placement and removal of the homogenizing tube, reset of the cleaning mechanism, and preparation for cleaning the homogenizing rod with a single pull, simplifying the operation process. The wiping components (door panel, absorbent cotton) employ an automatic reset design with torsion springs to ensure unobstructed movement of the homogenizing rod, and the absorbent cotton is periodically squeezed by a squeezing block to expel moisture, extending its service life.